CORALE-SeroNet Admin Core

CORALE-SeroNet 管理核心

基本信息

批准号：
10222433
负责人：
Susan Cheng
金额：
$ 34.63万
依托单位：
CEDARS-SINAI MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-30 至 2022-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10222433
关键词：
2019-nCoV Address Administrative Coordination Advisory Committees Advocate Annual Reports Basic Science Bioinformatics Budgets Clinical Research Clinical Sciences Collaborations Communication Communities Data Set Educational workshop Ensure Evaluation Feedback Generations Goals Immune Immunity Inflammatory Response Infrastructure Investigation Knowledge Leadership Letters Monitor Participant Patients Policies Population Sciences Predisposition Preparation Productivity Progress Reports Publications Reporting Research Research Personnel Research Project Grants Resource Allocation Resource Sharing Resources Scientist Services Structure Therapeutic Training Activity Translating Translational Research Translations Vision Work biobank data dissemination data sharing meetings operation organizational structure programs public repository recruit

项目摘要

ABSTRACT for Administrative Core The Administrative Core will provide a centralized, coordinated infrastructure for effectively supporting, evaluating, and stimulating progress towards the overall scientific goals of the CORALE-SeroNet U54 Program. The Core led by the Program Directors (Drs. Susan Cheng, Jane Figueiredo, and Michael Karin) will interact with Internal and External Advisory Committees and a Community Advisory Board and will provide regular feedback on programmatic initiatives and progress toward achieving the following goals. First, to provide leadership to ensure overall program productivity and effective collaboration across the SeroNET consortium. The Administrative Core will provide: (a) centralized and efficient administrative support and coordination of all CORALE-U54 activities and all collaborative efforts across the SeroNet consortium; (b) regular monitoring and evaluation of all project activities and generation of reports for internal and external stakeholders including assessments of opportunities for translation between basic and clinical research and the most effective allocation of resources; (c) engagement with advisory committees and external organizations, including other SeroNet centers and external investigators regarding progress toward the overall goals of SeroNet and opportunities for augmenting or integrating scientific and training activities; (d) financial administrative support to ensure appropriate management of budgets and financial resources; (e) support to ensure research compliance and integrity of all research programs; and, (f) administrative coordination for the dissemination of data and results, including data sharing and publication of all research findings. In particular, the Leadership Administrative Core has an active communication plan and resources for disseminating our ongoing findings to the broader clinical, research and lay communities. Second, the Administrative core will provide organizational structure and management support for the Resource Cores. The Administrative Core will provide an efficient and centralized administrative structure to support all activities of the two Cores: (a) Recruitment and Biobanking Core (RBC), and (b) the Immune Bioanalytics Core (IBC). Thirdly. The Administrative Core will provide organizational structure and management to collaborate within SeroNet and beyond. Our vision is to develop and manage a research program that will integrate our team of population, clinical, translational, and basic science scientists and unique patients resources with the broader scientific community led by SeroNET to meet the urgent need to understand the underlying mechanisms and potential therapeutic approaches to address key knowledge gaps regarding SARS-CoV-2 susceptibility and potential for immunity.

行政核心摘要行政核心将提供集中、协调的基础设施，以有效支持、评估并促进 CORALE-SeroNet U54 计划总体科学目标的进展。由项目总监（Susan Cheng 博士、Jane Figueiredo 和 Michael Karin）领导的核心人员将进行互动与内部和外部咨询委员会以及社区咨询委员会合作，并将定期提供关于计划举措和实现以下目标的进展的反馈。首先，要提供领导力，以确保整个项目的生产力和整个 SeroNET 联盟的有效协作。行政核心将提供： (a) 集中、高效的行政支持和协调 CORALE-U54 活动以及整个 SeroNet 联盟的所有协作努力； (b) 定期监测和评估所有项目活动并为内部和外部利益相关者生成报告，包括评估基础研究和临床研究之间的转化机会以及最有效的分配资源； (c) 与咨询委员会和外部组织（包括其他 SeroNet）合作中心和外部研究者关于 SeroNet 总体目标的进展以及机会加强或整合科学和培训活动； (d) 财政行政支持，以确保适当管理预算和财政资源； (e) 支持确保研究合规性和所有研究项目的完整性； (f) 传播数据和结果的行政协调，包括数据共享和所有研究成果的发布。特别是领导行政核心拥有积极的沟通计划和资源，可将我们持续的发现传播到更广泛的临床领域，研究和非专业社区。其次，行政核心将提供组织结构和对资源核心的管理支持。行政核心将提供高效、集中的支持两个核心所有活动的行政结构： (a) 招聘和生物样本库核心 (RBC)， (b) 免疫生物分析核心 (IBC)。第三。行政核心将提供组织 SeroNet 内部及外部协作的结构和管理。我们的愿景是开发和管理研究计划将整合我们的人口、临床、转化和基础科学科学家团队以及由 SeroNET 领导的更广泛科学界的独特患者资源，以满足迫切需要了解潜在的机制和潜在的治疗方法，以解决关键的知识差距关于 SARS-CoV-2 的易感性和免疫潜力。