Leveraging Bio-Cultural Mechanisms to Maximize the Impact of Multi-Level Preventable Disease Interventions with Southwest Populations

利用生物文化机制最大限度地发挥多层次可预防疾病干预措施对西南人群的影响

• 批准号: 10153465
• 负责人: Flavio Francisco Marsiglia
• 金额: $ 132.43万
• 依托单位: ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-30 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10153465
• 关键词: Acculturation; Address; Adolescent; Area; Arizona; Award; Behavior; Behavioral; Biological; Biological Factors; Cardiometabolic Disease; Child; Chronic Disease; Collaborations; Communities; County; Demographic Transitions; Development; Diet; Discipline; Disease; Environment; Family; Fostering; Funding; Future; Health; Health Food; Health Status; Health behavior; Household; Household and Family; Incubators; Individual; Interdisciplinary Study; Intervention; Intervention Studies; Knowledge; Latino; Life; Location; Measurable; Metabolic Diseases; Mexico; Mission; Morbidity - disease rate; Outcome; Persons; Pharmaceutical Preparations; Physical activity; Pilot Projects; Policies; Population; Population Heterogeneity; Positioning Attribute; Postdoctoral Fellow; Process; Productivity; Progress Reports; Public Health; Quality of life; Readiness; Research; Research Design; Research Personnel; Research Project Grants; Research Training; Risk; Risk Factors; Scholarship; Series; Solid; Specialized Center; Substance abuse problem; Testing; Training; Translating; Underserved Population; United States National Institutes of Health; Vulnerable Populations; Youth; base; community center; community partnership; community setting; contextual factors; design; early-career faculty; efficacious intervention; ethnic minority population; health disparity; health disparity populations; health equity; improved; innovation; interest; mortality; next generation; prevent; preventive intervention; programs; protective factors; racial and ethnic; research and development; social; social culture; social determinants; social health determinants; substance use; theories; therapy design

Leveraging Biocultural Mechanisms to Increase the Impact of Multi-level Preventable Disease Interventions with Southwest Populations Project Summary/Abstract The proposed U54 Specialized Center will advance knowledge on how to prevent cardiometabolic disease and substance abuse disorders among the health disparities populations of the Southwest. The Southwest Interdisciplinary Research Center (SIRC) has accumulated invaluable expertise in this area for the past 10 years as ASU's Exploratory Center of Excellence (NIMHD/NIH P20MD002316). The stark unmet health needs of the Southwest communities, the strong transdisciplinary team of researchers assembled for this application, and the existing solid community partnerships make this application highly significant. The Specialized Center will leverage SIRC's accumulated knowledge on cultural and social determinants of health and health disparities and will integrate biological, sociocultural and other contextual factors into efficacious, culturally grounded and impactful health interventions. We will focus on understanding the protective and risk effects of interpersonal family and household factors, the community environment, and individual health behaviors on specific biological health outcomes. The Specialized Center will extend SIRC's integrated, multilevel, social determinants approach to include biocultural mechanisms within an Ecodevelopmental Theory framework. The proposed center will significantly enhance SIRC's research impact through a research focus on preventing cardio metabolic disease and substance abuse disorders through culturally appropriate and efficacious interventions. The proposed research is innovative because it will investigate how protective and risk factors that are common to various chronic diseases and disorders manifest themselves among racial/ethnic minority populations of the Southwest, with an emphasis on the sociocultural and biological determinants of health disparities. The two proposed main research projects will target potentially modifiable youth behaviors associated with cardiometabolic disease and with substance abuse disorders (i.e., physical activity, and quality of diet, access to healthy foods, family functioning, acculturation, substance use, and illegal drug availability). The resulting findings will inform the design and testing of efficacious interventions that can strengthen protective factors and counteract risk factors operating within the multiple ecological domains of a young person's life. The center will conduct the two related main research projects to increase the impact of efficacious interventions by advancing knowledge on how cultural processes influence biological vulnerabilities (i.e., biocultural mechanisms). Early career faculty and postdocs will increase their capacity to conduct health dipartites research through a comprehensive investigator development and pilots research incubator initiative. The center will implement the research projects and future pilots in close and equitable partnership with communities of the Southwest. In partnership with the SIRC Community Advisory Board, the center will broadly disseminate and translate the knowledge generated by the studies and pilots to policy, practice, and lay stakeholders through an innovative dissemination plan.

利用生物文化机制增加多层次的影响 西南地区人群的可预防疾病干预措施 项目概要/摘要 拟议的 U54 专业中心将增进有关如何预防心脏代谢疾病和 西南地区健康差异人口中的药物滥用障碍。西南地区 跨学科研究中心 (SIRC) 在过去 10 年来在该领域积累了宝贵的专业知识 多年担任亚利桑那州立大学卓越探索中心 (NIMHD/NIH P20MD002316)。未满足的严峻健康需求 西南社区的强大的跨学科研究团队为此应用而组建， 现有的稳固的社区合作伙伴关系使该应用程序具有非常重要的意义。专业中心 将利用 SIRC 在健康和健康的文化和社会决定因素方面积累的知识 差异，并将把生物、社会文化和其他背景因素纳入有效的、文化的 扎根且有效的健康干预措施。我们将重点了解的保护和风险影响 人际家庭及家庭因素、社区环境、个人健康行为等对 具体的生物健康结果。该专业中心将扩展 SIRC 的综合性、多层次、社会性 决定因素方法将生物文化机制纳入生态发展理论框架内。这 拟建中心将通过重点研究预防疾病，显着增强 SIRC 的研究影响力 通过文化上适当和有效的方法来治疗心脏代谢疾病和药物滥用疾病 干预措施。拟议的研究具有创新性，因为它将调查保护性因素和风险因素如何影响 各种慢性疾病和病症常见的疾病在少数种族/族裔中表现出来 西南地区人口，重点关注健康的社会文化和生物决定因素 差异。拟议的两个主要研究项目将针对潜在可改变的青少年行为 与心脏代谢疾病和药物滥用障碍（即体力活动和质量 饮食、获得健康食品、家庭功能、文化适应、物质使用和非法药物供应）。 由此产生的结果将为有效干预措施的设计和测试提供信息，这些干预措施可以加强 保护因素并抵消在幼年的多个生态领域内起作用的风险因素 人的一生。该中心将开展两个相关的主要研究项目，以提高影响力 通过增进有关文化进程如何影响生物脆弱性的知识来进行有效的干预 （即生物文化机制）。早期职业教师和博士后将提高他们进行健康管理的能力 通过全面的研究者发展和试点研究孵化器倡议来开展两方面的研究。 该中心将与以下机构建立密切和平等的合作伙伴关系来实施研究项目和未来的试点 西南地区的社区。该中心将与 SIRC 社区咨询委员会合作 广泛传播研究和试点所产生的知识并将其转化为政策、实践和 通过创新的传播计划让利益相关者受益。

项目成果

A performance review of novel adiposity indices for assessing insulin resistance in a pediatric Latino population.

用于评估拉丁裔儿童胰岛素抵抗的新型肥胖指数的性能审查。

• 发表时间: 2022
• 作者: McGraw, Mac B;Kohler, Lindsay N;Shaibi, Gabriel Q;Mandarino, Lawrence J;Coletta, Dawn K
• 通讯作者: Coletta, Dawn K

Effects of Familism and Family Cohesion on Problem Behaviors among Adolescents in Mexican Immigrant Families in the Southwest U.S.

家庭主义和家庭凝聚力对美国西南部墨西哥移民家庭青少年问题行为的影响

• 发表时间: 2009-07-01
• 作者: Marsiglia, Flavio F;Parsai, Monica;Kulis, Stephen;Southwest Interdisciplinary Research Center
• 通讯作者: Southwest Interdisciplinary Research Center

Perceived ethnic discrimination versus acculturation stress: influences on substance use among Latino youth in the Southwest.

感知到的种族歧视与文化适应压力：对西南部拉丁裔青年物质使用的影响。

• 发表时间: 2009-12
• 影响因子: 5
• 作者: Kulis, Stephen;Marsiglia, Flavio Francisco;Nieri, Tanya
• 通讯作者: Nieri, Tanya

Engaging families to prevent substance use among Latino youth.

让家庭参与防止拉丁裔青少年滥用药物。

• 发表时间: 2010-10
• 作者: Chen, Angela Chia;Gance;Kopak, Albert;Haas, Steven;Gillmore, Mary
• 通讯作者: Gillmore, Mary

Spirituality and religion: intertwined protective factors for substance use among urban American Indian youth.

灵性和宗教：美国城市印第安青年物质使用的相互交织的保护因素。

• 发表时间: 2012-09
• 作者: Kulis, Stephen;Hodge, David R;Ayers, Stephanie L;Brown, Eddie F;Marsiglia, Flavio F
• 通讯作者: Marsiglia, Flavio F