Clinical Sciences Core (Core C)

临床科学核心（核心 C）

• 批准号: 10153672
• 负责人: David W Haas
• 金额: $ 66.37万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-04-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10153672
• 关键词: AIDS clinical trial group; AIDS/HIV problem; Academic Medical Centers; Acquired Immunodeficiency Syndrome; Agreement; Applications Grants; Award; Biological; Caring; Centers for Disease Control and Prevention (U.S.); Clinic; Clinical; Clinical Research; Clinical Sciences; Collaborations; Communities; Comprehensive Health Care; Consultations; County; Coupled; Data; Data Science Core; Data Set; Databases; Development; Doctor of Philosophy; Environment; Epidemic; Epidemiology; Extramural Activities; Fostering; Foundations; Funding; Goals; Grant; HIV; HIV Infections; HIV-1; HIV/HCV; Harm Reduction; Health; Hepatitis C virus; Infection; Infrastructure; Institution; Investigation; Joints; Laws; Leadership; Manuscripts; Mission; Modeling; Outcome; Participant; Patient Recruitments; Persons; Policies; Postpartum Period; Prevalence; Process; Publications; Publishing; Research; Research Design; Research Personnel; Research Project Grants; Research Support; Resources; Risk; Risk Assessment; Science; Scientist; Services; Southeastern United States; Specimen; Support Groups; Tennessee; Time; Tissues; Translational Research; United States National Institutes of Health; Woman; Work; aged; base; career; career development; cohort; community based participatory research; database design; male; medical schools; next generation; programs; recruit; research study; response; rural area; success; urban area; volunteer

Clinical Sciences Core – PROJECT SUMMARY The Tennessee Center for AIDS Research (CFAR) is located in the Southeastern US, the region with both the greatest number of new HIV-1 infections, and of persons living with HIV. The CFAR is a four-way partnership between a research-intensive institution (Vanderbilt University Medical Center), a historically black medical college (Meharry Medical College), an academically engaged state health department (Tennessee Department of Health), and an highly evolved HIV-focused community-based organization (Nashville CARES). This CFAR's institutional and community environment is rich in opportunity, and with a culture of engagement and collaboration. The Clinical Sciences Core (CSC) fills major gaps in the local research environment, and in so doing supports the mission of the CFAR to reduce the overall burden of HIV/AIDS through the pursuit of National Institutes of Health high priorities for HIV/AIDS research, with the ultimate goal of ending the HIV epidemic. Access to research study participants and associated biospecimens, and to large clinical cohort datasets, are essential for high-quality clinical and translational HIV research. Since this CFAR was established in 2015, the CSC has been integral to its success. The CSC is essential for early stage investigators on their path toward independent extramural funding, which equips the next generation of research scientists while also serving to expand this CFAR's HIV research portfolio and funding base. Building upon the expertise and collective infrastructure of the CFAR, coupled with the addition of a strong, established community partner in CARES, we will pursue the following three specific aims: 1) To propel the use of observational databases for high impact HIV clinical and translational research; 2) To support research projects that require access to study volunteers and associated biological specimens, and; 3) To support research opportunities for MMC investigators, including team science.

临床科学核心——项目摘要 田纳西州艾滋病研究中心 (CFAR) 位于美国东南部，该地区拥有 CFAR 是一种四方伙伴关系。 一个研究密集型机构（范德比尔特大学医学中心），一个历史悠久的黑人医学中心 学院（梅哈里医学院），一个从事学术工作的州卫生部门（田纳西州部门） 健康），以及高度发展的以艾滋病毒为中心的社区组织（纳什维尔关怀）。 机构和社区环境充满机会，并具有参与和参与的文化 临床科学核心（CSC）填补了当地研究环境的重大空白。 所做的事情支持了 CFAR 的使命，即通过追求国家目标来减轻艾滋病毒/艾滋病的总体负担 卫生研究院高度重视艾滋病毒/艾滋病研究，最终目标是结束艾滋病毒流行。 访问研究参与者和相关生物样本以及大型临床队列数据集 自 2015 年建立以来，高质量的临床和转化 HIV 研究至关重要。 CSC 对其成功至关重要。CSC 对于早期研究人员的成功至关重要。 独立的校外资助，为下一代研究科学家提供装备，同时也服务于 以专业知识和集体为基础，扩大 CFAR 的艾滋病毒研究组合和资金基础。 CFAR 的基础设施，再加上 CARES 中强大、成熟的社区合作伙伴的加入，我们 将追求以下三个具体目标： 1) 推动高影响艾滋病毒观察数据库的使用 临床和转化研究；2) 支持需要研究志愿者和 相关生物标本，以及；3) 支持 MMC 研究人员（包括团队）的研究机会 科学。