PLANNING A PROGRAM OF RESEARCH IN PROSTATE CANCER

规划前列腺癌研究计划

• 批准号: 2113785
• 负责人: PHILIP JOHN WALTER
• 金额: $ 28.31万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-30 至 1999-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2113785
• 关键词: African American; androgens; cancer risk; carotenoids; cell growth regulation; diet; dietary constituent; disease /disorder model; family genetics; gene therapy; health science research; human subject; human therapy evaluation; laboratory rat; neoplasm /cancer therapy; nonhuman therapy evaluation; nutrition related tag; occupational hazard; pesticides; prostate neoplasms; racial /ethnic difference; selenium; tocopherols; transcription factor

The researchers at Duke University will collaborate in the planning and development of a Prostate Cancer Program at Duke University. Components for planning and development, the recruitment of new Investigators and funding to develop a Pilot Program will be established. Pilot projects will be particularly focused to address the issues of occupational exposure, diet, familial association and race as well as innovative concepts in therapy and cellular regulation. A specific orientation will be the ascertainment of African-American males to explain their apparently higher risk of onset of prostate carcinoma in that population. A wide research base in cancer will be the basis upon which to build hypothesis directed research pilot programs to gain sufficient information to justify application for formal R01 support for such prostate cancer directed research activities. An Internal Advisory Board has been established which will direct the planning and development of such activities.

杜克大学的研究人员将在计划中合作 开发杜克大学的前列腺癌计划。成分 为了计划和开发，新调查人员的招聘 将建立开发试点计划的资金。试点项目 将特别专注于解决职业问题 曝光，饮食，家庭协会和种族以及创新 治疗和细胞调节的概念。特定的方向将 确定非洲裔美国男性以解释自己的 显然，该人群中前列腺癌发作的风险更高。 癌症的广泛研究基础将是建立的基础 假设有指导研究试点计划，以获得足够的 信息以证明对此类正式R01支持的申请合理 前列腺癌指导研究活动。内部顾问委员会 已经建立了将指导的计划和发展 这样的活动。