Training Program in Resuscitation Science

复苏科学培训计划

• 批准号: 10549292
• 负责人: Michael William Donnino
• 金额: $ 53.7万
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-02-01 至 2026-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10549292
• 关键词: Resuscitation; Science; Training Programs

Abstract We aim to provide advanced multidisciplinary research training in the emerging field of resuscitation science to physician- and PhD-scientists to jump-start their progression to independence as investigators. Resuscitation science is defined in this proposal as the medical treatment of ischemia-perfusion injury (i.e., cardiac arrest), shock (i.e., tissue hypo-perfusion), acute lung injury, and subsequent other-organ injury such as renal impairment. Collectively, these conditions afflict millions of patients every year and are associated with high mortality and substantial morbidity. The proposed program will help alleviate a critical shortage of well-trained and well-funded resuscitation science investigators. Most critically, the cross-discipline research training afforded to program trainees should make them well-positioned to advance the field as a whole due to the common risk factors, pathogenic mechanisms, and outcome phenotypes shared by conditions requiring resuscitation. The strong multidisciplinary faculty/mentorship T32 program team is comprised of resuscitation scientists who excel in both research and mentorship. Their expertise spans the fields of emergency medicine, cardiology, nephrology, as well as pulmonary critical care, anesthesia critical care, surgical critical care, and pediatric critical care. Research conducted by the mentorship team uses a wide spectrum of approaches which include clinical trials, epidemiology/data science, and laboratory science, with many mentors combining two or more approaches. Trainees in our program will focus their research training in one of these approaches; all will however receive preliminary training in, and multidisciplinary exposure to, all three approaches. The NHLBI has noted this sort of integration is critical for breakthrough advances in public health [1], and our emphasis on this point will produce truly multidisciplinary, and in many cases translational investigators. The specific fellowship training will combine a formalized didactic curriculum with a mentored project, training in research communication, and career mentorship. The didactic program will draw from courses run by Harvard Catalyst (CTSA), the Harvard School of Public Health, and the Center for Resuscitation Science and will include required common and track-specific core courses and elective courses. Each fellow’s coursework will be individually tailored to match personal objectives and goals developed with the mentorship team. The individualized mentored research project will be designed and executed by the fellow under the guidance of his or her primary mentor with assistance from other members of the program faculty. Fellows will be encouraged to collaborate with mentors and fellows outside of their chosen track to broaden their research expertise. Training in communication of research results through conference presentations and research papers, grant writing, and general career development advice will be valuable additions to the core research training. At the completion of this program fellows will be expected to meet defined metrics - multiple abstract presentations, manuscript publications, and grant submissions - all key steps in their path toward research independence.

抽象的 我们旨在在复苏科学的新兴领域提供高级的多学科研究培训 博士学位科学家将他们作为调查人员的独立发展启动。复苏 该提案中的科学被定义为缺血 - 灌注损伤的医疗（即心脏骤停）， 休克（即组织低渗透），急性肺损伤和随后的其他器官损伤，例如肾脏 损害。总的来说，这些状况每年都会困扰数百万患者，并且与高有关 死亡率和大量发病率。拟议的计划将有助于缓解训练有素的严重短缺 和资金充足的复苏科学研究者。最关键的是，跨学科研究培训提供了 由于普遍的风险 需要复苏的条件共享的因素，致病机制和结果表型。 强大的多学科教师/指导T32计划团队完成了卓越的复苏科学家 在研究和心态中。他们的专业知识涵盖了急诊医学，心脏病学领域， 肾脏病以及肺重症监护，麻醉重症护理，手术重症监护和小儿关键 关心。 Mentalship团队进行的研究采用了各种方法，包括临床 试验，流行病学/数据科学和实验室科学，许多月经结合了两个或更多 方法。我们计划中的学员将把研究培训集中在其中一种方法上；一切都会 但是，接受所有三种方法的初步培训和多学科接触。 NHLBI拥有 注意到这种整合对于公共卫生的突破性进步至关重要[1]，我们对此的重视 观点将产生真正的多学科，在许多情况下翻译研究人员。具体的奖学金 培训将将正式的教学课程与一个指导项目，研究培训相结合 沟通和职业心态。教学计划将从哈佛大学催化剂开设的课程中获取 （CTSA），哈佛公共卫生学院和复苏科学中心，将包括所需的 普通和特定的核心课程和选修课程。每个家伙的课程将单独进行 量身定制的是与Mentalship团队一起开发的个人对象和目标。个性化 指导研究项目将由该研究员在其主要的指导下设计和执行 在该计划教师的其他成员的协助下，导师。鼓励研究员合作 在他们选择的轨道之外的导师和研究员，扩大他们的研究专业知识。培训 通过会议演讲和研究论文，赠款写作和 一般职业发展建议将是核心研究培训的宝贵补充。完成 该计划的研究员将有望符合定义的指标 - 多个抽象演示文稿，手稿 出版物和授予提交 - 所有关键步骤都在其发展独立性的道路上。