Clinical Training in Rheumatology
风湿病学临床培训
基本信息
- 批准号:10492976
- 负责人:
- 金额:$ 156.97万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:
- 资助国家:美国
- 起止时间:至
- 项目状态:未结题
- 来源:
- 关键词:AccreditationAdult-Onset Still&aposs DiseaseAgonistAmericanAnkylosing spondylitisAntibodiesAreaArthritisBlood VesselsBusinessesCertificationChildChildhoodCitiesClinicClinicalClinical ResearchCommunity HealthConnective Tissue DiseasesConsultationsContinuity of Patient CareDegenerative polyarthritisDermatomyositisDiseaseDistrict of ColumbiaEducational CurriculumEducational process of instructingEnrollmentEventFacultyFellowshipFellowship ProgramFeverFibromyalgiaFunctional disorderGeneticGoutGuidelinesInclusion Body MyositisInfectious ArthritisInflammatoryInfusion proceduresInheritedInpatientsInstitutionInvestigationJanus kinaseJournalsLength of StayMedical ExaminersMedical centerMelorheostosisMentorsMolecularMyositisNational Institute of Arthritis and Musculoskeletal and Skin DiseasesNatural HistoryNeonatal Onset Multisystem Inflammatory DiseaseOralOsteoporosisOutcomeOutpatientsPPAR gammaPathogenesisPatient CarePeriodicityPeroxisome Proliferator-Activated ReceptorsPhase Ib Clinical TrialPositioning AttributePreventionProtocols documentationPseudogoutResearchResearch ActivityResearch Project GrantsResearch TrainingRheumatismRheumatoid ArthritisRheumatologyRoleRotationSafetySarcoidosisScienceServicesSiteSocietiesSpinal FusionSpondylarthritisSyndromeSystemic Lupus ErythematosusSystemic SclerodermaTNF geneTimeTrainingTraining ProgramsTranslational ResearchUnited States National Institutes of HealthVasculitisWashingtoncareercase-by-case basisclinical careclinical centercongenital immunodeficiencycytokinegraduate medical educationimmunoregulationkinase inhibitorlecturesmeetingsminority communitiesprogramssymposiumsystemic juvenile idiopathic arthritisward
项目摘要
Each academic year the Rheumatology Fellowship Program matriculates one, two or three rheumatology fellows who will complete two years of subspecialty training. Following these two years, fellows will have fulfilled the American Board of Medical Examiners requirements to be eligible to sit for the Rheumatology Board examination.
The first year of training is clinical and fellows participate in a variety of continuity care clinics. These clinics include the NIAMS Community Health Clinic, NIAMS Clinical Center Arthritis Clinic, and NIAMS Clinical Center Pediatric Rheumatology Clinic. In addition to these clinics, other patient care activities include the NIAMS inpatient ward, and the inpatient and outpatient consultative services. First year fellows also spend time participating in a Day Hospital infusion service. All fellows participate in core curriculum lectures that provide didactics concerning general rheumatology during the first five weeks of training. Additional teaching sessions include weekly core lectures, business meetings, clinical journal clubs, Rheumatology Grand Rounds, and a weekly translational journal club. Other core conferences include Director's Rounds, Intra-City Grand Rounds, and the District of Columbia Rheumatism Society meetings. Attendance is required of all trainees to NIH-sponsored events to fulfill the requirements for training.
During the first year, all fellows are encouraged to discuss research activities with faculty such that in the second year they can begin a mentored research activity. During the second year of fellowship, ACGME guidelines mandate a continuity care clinic and didactic activities. This leaves up to 80% protected time for the fellow to gain a meaningful research exposure. The research is encouraged to be either basic bench science or clinical research. Recent examples of research projects include the study of hereditary forms of inclusion body myositis, study of monogenic periodic fever syndromes, and examination of anti-cytokine antibody profiles.
The NIAMS Clinical Program also serves as a clinical and research training site for the Children's National Medical Center (CNMC) (Washington, DC) - NIH Pediatric Rheumatology Fellowship Training Program. The first year of clinical training is primarily at CNMC, with rotations through NIAMS rheumatology clinics. Fellows who match with research mentors located at the NIH may spend the final two years of their training at NIH and participate in clinical care at both institutions. On a case by case basis, uniquely meritorious candidates may be accepted for combined med-peds rheumatology training leading to dual certification.
The Clinical Fellowship program is vital to clinical research at the NIH Clinical Center because all fellows provide care for patients enrolled in the following protocols:
03-AR-0173 Studies of the Natural History and Pathogenesis of Neonatal Onset Multisystem Inflammatory Disease (NOMID)
11-AR-0223 Studies on the Natural History and Pathogenesis of Spondyloarthritis
18-AR-0081 Investigation of the natural history, genetics and pathophysiology of systemic juvenile idiopathic arthritis and adult onset Stills disease and related inflammatory conditions
99-AR-0004 Molecular Basis of Primary Immunodeficiencies
94-AR-0066 Studies of the Pathogenesis and Natural History of Systemic Lupus Erythematosus (SLE)
15-AR-0185 Safety of tofacitinib, an oral Janus kinase inhibitor, in Systemic Lupus Erythematosus; a Phase Ib clinical trial and associated mechanistic studies
15-AR-0060 The role of PPAR-gamma agonists in immunomodulation and vascular prevention in SLE (PPAR-SLE)
14-AR-0200 Studies of the natural history, pathogenesis and outcome of idiopathic systemic vasculitis
91-AR-0196 Studies on the natural history and pathogenesis of polymyositis, dermatomyositis, and related diseases
00-AR-0222 Studies of the pathogenesis and natural history of arthritis and related conditions
15-AR-0165 Studies of the natural history, pathogenesis and outcome of melorheostosis, a rare osteosclerotic disease
01-AR-0227 Natural history of rheumatic disease in minority communities
04-AR-0205 Progression of spinal fusion in ankylosing spondylitis
13-AR-0056 Stopping anti-TNF agents in rheumatoid arthritis (STARA) trial
每个学年,风湿病学奖学金计划都将一名,两个或三个风湿病学研究员入学,他们将完成两年的专科培训。在这两年之后,研究员将满足美国体检医师委员会的要求,有资格参加风湿病委员会考试。
培训的第一年是临床,研究员参加了各种连续性护理诊所。这些诊所包括NIAMS社区健康诊所,NIAMS临床中心关节炎诊所和NIAMS临床中心小儿风湿病诊所。除这些诊所外,其他患者护理活动还包括NIAMS住院病房以及住院和门诊咨询服务。第一年的研究员还花时间参加一日医院的输液服务。所有研究员都参加了核心课程讲座,这些讲座提供了有关培训的前五个星期提供有关普通风湿病学的教学。额外的教学课程包括每周核心讲座,商务会议,临床期刊俱乐部,风湿病学大回合和每周翻译期刊俱乐部。其他核心会议包括董事回合,城市内大回合和哥伦比亚特区风湿病协会会议。所有受训人员都需要参加NIH赞助的活动,以满足培训的要求。
在第一年,鼓励所有研究员与教师讨论研究活动,以便在第二年开始进行指导的研究活动。在研究金的第二年,ACGME指南要求连续性护理诊所和教学活动。这给同胞获得有意义的研究暴露时,最多保护了80%的时间。鼓励研究是基本的基础科学或临床研究。研究项目的最新例子包括研究遗传形式的包容体肌炎,单基因周期性发烧综合征的研究以及检查抗促动物抗体谱的研究。
NIAMS临床计划还作为儿童国家医疗中心(CNMC)(华盛顿特区)的临床和研究培训站点 - NIH儿科风湿病学研究金培训计划。临床培训的第一年主要是在CNMC进行,并通过NIAMS风湿病诊所旋转。与位于NIH的研究导师相匹配的研究员可能会在NIH培训的最后两年,并在这两个机构参加临床护理。在情况下,可以接受独特的有功候选人,用于合并的药物风湿病学培训,从而获得双重认证。
临床奖学金计划对NIH临床中心的临床研究至关重要,因为所有同伴为参加以下方案的患者提供护理:
03-AR-0173关于新生儿发作多系统炎症性疾病(NOMID)的自然病史和发病机理的研究
11-AR-0223关于脊椎关节炎的自然病史和发病机理的研究
18-ar-0081对全身少年特发性关节炎和成人发病剧院疾病以及相关炎症状况的自然史,遗传学和病理生理的研究调查
原发性免疫缺陷的99-AR-0004分子基础
94-AR-0066关于全身性红斑狼疮(SLE)的发病机理和自然历史的研究
15-AR-0185 TOFACITINIB(一种口服Janus激酶抑制剂)在全身性红斑狼疮的安全性; IB期临床试验和相关机理研究
15-ar-0060 PPAR-GAMMA激动剂在SLE(PPAR-SLE)中的免疫调节和血管预防中的作用
14-AR-0200对特发性全身血管炎的自然病史,发病机理和结局的研究
91-AR-0196关于多肌炎,皮肤炎和相关疾病的自然病史和发病机理的研究
00-AR-0222关于关节炎和相关疾病的发病机理和自然史的研究
15-AR-0165关于自然史,发病机理和情绪低下的结果的研究,这是一种罕见的骨硬化疾病
01-AR-0227少数民族疾病的自然历史
04-AR-0205强直性脊柱炎中脊柱融合的进展
13-ar-0056在类风湿关节炎(Stara)试验中停止抗TNF药物
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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