Infection and Immunity: The Pathogenesis of Host-Microbe Interactions

感染和免疫：宿主-微生物相互作用的发病机制

• 批准号: 10492947
• 负责人: Paul Dunman
• 金额: $ 26.4万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10492947
• 关键词: Immunity; Infection; Pathogenesis; host-microbe interactions

ABSTRACT The current SARS-CoV-2 pandemic has made it readily apparent that infectious diseases are a major threat to U.S. health. The goal of this predoctoral T32 program is to train the next generation of researchers in microbiology, and to prepare them with the skills necessary to address the nation’s critical needs in the battle against infectious disease. To do this, we have developed a training program that takes a student-centric, autonomy-supportive approach with the goal of training self-motivated, independent research scientists who are well prepared for diverse research careers. Innovative program features include: an autonomy-supportive educational approach that encourages self-directed exploration of diverse career options; instruction in the “soft skills” necessary for research career success; and the establishment of faculty mentoring practices that support student autonomy and self-directed learning. The program’s renewal expands and enhances our 6 overarching objectives. First, it will provide outstanding interdisciplinary research training in microbial pathogenesis, in part by leveraging unique opportunities created by signature institutional NIH-funded centers that include the Center of Excellence for Influenza Research and Surveillance, Environmental Health Science Center, Vaccine and Treatments Evaluation Unit, and the University of Rochester’s Clinical and Translational Sciences Institute. Second, it will provide outstanding education in microbiology and pathogenesis, which incorporates four major components: 1. a streamlined required core didactic curriculum; 2. required program-specific experiences (including courses, workshops and career/professional development activities); 3. optional elective courses and experiences designed to encourage student exploration, and 4. hands-on thesis research. Third, it will train self-directed, autonomous scientists who are prepared for diverse research career options. To facilitate this, all trainees will complete a personality inventory and an annual Individualized Development Plan (IDP), participate in “Microbiology Career Stories” and other activities offered by the UR’s Broadening Experiences in Scientific Training program which provides avenues for diverse career exploration, and offered the opportunity to participate in extramural internships. Fourth, we provide training in the “soft-skills” necessary for success through participation in a “Leadership Academy” program and supervised training in mentoring. Fifth, we will continue to improve faculty mentoring practices through required instruction in autonomy supportive mentoring practices involving IDPs and “Mentor our Mentors” workshops. Sixth, we will develop a new UR Student Lifecycle program to longitudinally track program alumni, obtain experiential feedback to further optimize the program, assess career outcomes, and establish a formal portal to facilitate trainee networking and career advancement.

抽象的 当前的SARS-COV-2大流行很容易看出，感染疾病是主要的 对美国卫生的威胁。该尾部T32计划的目的是培训下一代研究人员 微生物学，并为他们准备满足战斗中国家关键需求所需的技能 反对传染病。为此，我们制定了一个以学生为中心的培训计划， 自主支持方法的目标是培训自我激励的独立研究科学家 为潜水员研究事业做好了充分的准备。创新计划的功能包括：自主支持 鼓励自我指导探索各种职业选择的教育方法； “柔软的说明 技能”为研究职业成功所必需的技能；建立教师的心理实践 学生的自主性和自我指导的学习。 该计划的续约扩展并增强了我们的6个总体目标。首先，它将提供 在微生物发病机理中出色的跨学科研究培训，部分是通过利用独特的 由签名机构NIH资助的中心创造的机会，其中包括卓越中心 流感研究与监视，环境健康科学中心，疫苗和治疗 评估部门，以及罗切斯特大学的临床与转化科学研究所。其次，它将 提供微生物学和发病机理方面的出色教育，其中包含四个主要组成部分：1。 简化所需的核心教学课程； 2。所需的计划特定经验（包括课程， 讲习班和职业/专业发展活动）； 3。可选的选修课程和经验 旨在鼓励学生探索和4。动手论文研究。第三，它将训练自我指导， 为潜水员研究职业做准备的自主科学家。为了促进这一点，所有学员都将 完成个性库存和年度个性化发展计划（IDP），参加 “微生物学业故事”以及UR在科学方面的扩展经验提供的其他活动 培训计划为潜水员职业探索提供途径，并提供了机会 参加壁外实习。第四，我们在成功的“软技能”中提供培训 参加“领导力学院”计划和心理培训。第五，我们将继续 通过自主支持心理实践中所需的说明来改善教师心理实践 涉及IDP和“指导我们的导师”研讨会。第六，我们将制定一个新的学生生命周期计划 要纵向跟踪计划校友，获得专家反馈以进一步优化该计划，评估 职业成果，并建立正式的门户，以促进受训者的网络和职业发展。