Administrative Core

行政核心

• 批准号: 10491820
• 负责人: Tracy T Batchelor
• 金额: $ 10.67万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-21 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10491820
• 关键词: Administrator; Adult Glioblastoma; Cancer Center; Catchment Area; Clinical; Clinical Trials; Collaborations; Communication; Communication Programs; Community Outreach; Complex; Dana-Farber Cancer Institute; Doctor of Medicine; Doctor of Philosophy; Electronic Mail; Faculty; Fostering; Funding; Funding Opportunities; General Hospitals; Genomics; Glioblastoma; Glioma; Goals; Grant; Hospitals; Human Resources; Image; Infrastructure; Institution; Leadership; Massachusetts; Medical; Mentorship; Monitor; Parents; Patients; Pharmacology; Pilot Projects; Principal Investigator; Research Personnel; Research Project Grants; Resources; SECTM1 gene; Scientist; Series; Site; Specialist; Structure; Students; Therapeutic; Training; Universities; Woman; Work; base; career development; community engagement; diversity and inclusion; drug development; experience; industry partner; inter-institutional; meetings; multidisciplinary; new therapeutic target; programs; ranpirnase; recruit; research and development; response; translational scientist

In response to a Funding Opportunity Announcement for multi-institutional teams to form a Glioblastoma Therapeutics Network (GTN) basic scientists and clinical/translational investigators from three institutions in the Dana-Farber/Harvard Cancer Center have joined forces with their counterparts in the Stanford Cancer Center to create the “Harvard/Stanford GTN”. The GTN study plan features three Projects an Administrative Core, a Pharmacological and Genomic Imaging Core and a proposed Network Coordinating Center (NCC). The Administrative Core will be based at Brigham and Women’s Hospital, the parent organization for the Harvard/Stanford GTN, and will serve as the coordinating center and hub for the four institutions comprising the program and all interactions with existing P30-supported resources for clinical trials. The core will coordinate internal and external components of this complex structure to foster and support multi-project, inter-disciplinary, and inter-institutional drug development research in adult glioblastoma. Core personnel include one GTN Principal Investigator, three Site Leads at the Harvard/Stanford GTN institutions, two scientific co-administrators, a program coordinator, two grants specialists, and an administrative assistant. There are five Specific Aims in the Administrative Core. In the First Aim, the core will develop and engage a multidisciplinary Internal Advisory Board to provide critical oversight of the overall Harvard/Stanford GTN program. In the Second Aim, the core will organize regular meetings of key stakeholders to foster collaboration, troubleshooting, and monitoring of progress. In the Third and Fourth Aims, the core will maintain a trans-institutional program for regular, internal and external electronic communication among Harvard/Stanford project and core co-leads, clinical trialists, the GTN Steering Committee, the NCC, NCI program officials, and industry partners. In the Fifth Aim, the core will engage with institutional leaders at Harvard and Stanford to promote diversity and inclusion throughout the Harvard/Stanford GTN program. The Administrative Core Leader, Tracy Batchelor, M.D., will serve as the overall Principal Investigator of the Harvard/Stanford GTN program with able assistance from Site Leads at Dana-Farber Cancer Institute (Patrick Wen, M.D.), Massachusetts General Hospital (Isabel Arrillaga, M.D., Ph.D.), and Stanford University (Michelle Monje, M.D., Ph.D.). This trans-institutional administrative team at Dana-Farber/Harvard Cancer Center and Stanford Cancer Center have worked together effectively on other multi-center, multi-project, NCI-sponsored glioma research projects.

为了回应跨机构团队形成胶质母细胞瘤的资助机会公告 Therapeutics网络（GTN）的基础科学家和来自三个机构的临床/转化调查员 达娜·法伯（Dana-Farber）/哈佛癌中心（Dana-Farber/Harvard Cancer Center 中心创建“哈佛/斯坦福GTN”。 GTN研究计划的特点是三个项目 行政核心，一种药理和基因组成像核心以及提议的网络 协调中心（NCC）。行政核心将位于杨百翰和妇女医院， 哈佛大学/斯坦福GTN的母公司组织，并将作为协调中心和枢纽 四个机构完成了该计划以及与现有P30支持的临床资源的所有互动 试验。核心将协调这种复杂结构的内部和外部组件，以促进和支持 成人胶质母细胞瘤的多项目，学科和机构间药物开发研究。核 人员包括一名GTN首席研究员，在哈佛/斯坦福GTN机构的三个地点。 两位科学协调员，一个计划协调员，两名赠款专家和一名行政助理。 行政核心有五个具体目标。在第一个目标中，核心将发展并参与 多学科的内部咨询委员会旨在对哈佛大学/斯坦福GTN进行严格监督 程序。在第二个目标中，核心将组织主要利益相关者的定期会议以促进 协作，故障排除和进度监控。在第三和第四目标中，核心将保持 用于常规，内部和外部电子通信的跨机构计划 哈佛大学/斯坦福大学项目和核心共同领导，临床试验员，GTN指导委员会，NCC，NCI 计划官员和行业合作伙伴。在第五目标中，核心将与机构领导人互动 哈佛和斯坦福大学在整个哈佛/斯坦福GTN计划中促进多样性和包容性。这 行政核心负责人，特雷西·巴切洛（Tracy Batchelor），医学博士，将担任总体调查员 哈佛/斯坦福GTN计划在Dana-Farber癌症研究所（Patrick 马萨诸塞州综合医院（M.D. Isabel Arrillaga，博士）和斯坦福大学（Michelle） Monje，M.D。，博士）。达纳 - 法伯/哈佛大学癌症中心的跨机构行政团队和 斯坦福癌症中心已经有效地在其他多中心，多项目的NCI赞助 神经瘤研究项目。