Administrative Core

行政核心

• 批准号: 10487471
• 负责人: Marjan Boerma
• 金额: $ 65.43万
• 依托单位: UNIV OF ARKANSAS FOR MED SCIS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-06-24 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10487471
• 关键词: Address; Adverse effects; Advisory Committees; Animals; Applications Grants; Area; Arkansas; Cancer Patient; Cancer Survivor; Centers of Research Excellence; Communication; Discipline; Doctor of Philosophy; Ensure; Environment; Evaluable Disease; Evaluation; Fees; Funding; Goals; Grant; Growth; Immune response; Infrastructure; Institution; Interdisciplinary Study; Intestines; Journals; Life; Malignant Neoplasms; Manuscripts; Medical; Mentors; Methods; Occupational activity of managing finances; Oncology; Patients; Peer Review; Persons; Phase; Pilot Projects; Program Development; Publications; Quality of life; Radiation Injuries; Research; Research Personnel; Role; Schedule; Science; Scientist; Series; Services; Structure; Survivors; Teacher Professional Development; Toxic effect; Toxicology; Translational Research; Universities; Writing; cancer therapy; design; disability; experience; improved; irradiation; meetings; multidisciplinary; novel strategies; operation; prevent; programs; recruit; side effect; success; synergism

PROJECT SUMMARY/ABSTRACT Many cancer patients and survivors suffer from adverse effects due to treatment that can arise both during and after the completion of cancer therapy. The COBRE Center for Studies of Host Response to Cancer Therapy supports investigators from various disciplines who 1) research the mechanisms by which cancer therapy causes adverse effects, 2) identify new methods for detecting side effects sooner, and 3) develop novel strategies to prevent or reduce side effects. The purpose of the Administrative Core (Core A) is to build a self-sustaining research Center by maximizing opportunities for investigators to succeed and by promoting interactions and synergy within the Center and with other research units in the institution. Core A will provide an efficient, integrated administrative infrastructure for the COBRE Center (Aim 1), accelerate scientific growth through faculty development and scientific advising (Aim 2), and expand and advance the Center toward self- sustainability (Aim 3). A primary function of the core is to provide administrative support for project leaders and to manage financial affairs for the Center as a whole. Core A ensures there is effective communication within and among the projects and cores. Additionally, the core provides the infrastructure for scientific advising and faculty development, which will encourage scientific progress for project leaders and will help integrate their efforts with those of other scientists on campus. With assistance of the External Advisory Committee, new project leaders will be recruited and selected to replace those who graduate from COBRE advisee status. The Center also will perform a systematic, objective evaluation of activities, project leaders and their research, scientific advising and faculty development programs, and core functions. This strategy will ensure the long-term success of the Center as an independent but well-integrated investigative unit on campus with a vibrant and synergistic research environment that comprehensively addresses the short-term and long-term side effects of cancer therapy.

项目摘要/摘要 许多癌症患者和幸存者因治疗而遭受不良影响，这两者都可能在 癌症治疗完成后。宿主对癌症治疗反应的毛cre研究中心 支持来自各个学科的研究者1）研究癌症治疗引起的机制 不良影响，2）确定更快地检测副作用的新方法，3）制定新的策略 预防或减少副作用。行政核心（核心A）的目的是建立一个自我维持的 研究中心通过最大化调查人员成功和促进互动的机会 中心内以及机构中的其他研究单位的协同作用。核心A将提供有效的， 毛绒中心的综合行政基础设施（AIM 1），通过 教师的发展和科学建议（AIM 2），并扩大和促进中心向自我发展 可持续性（目标3）。核心的主要功能是为项目负责人提供管理支持， 管理整个中心的财务事务。核心A可确保内部有有效的沟通 在项目和核心中。此外，核心为科学咨询和 教师发展，这将鼓励项目领导者的科学进步，并将有助于整合他们的 与校园其他科学家的努力。在外部咨询委员会的协助下，新项目 领导者将被招募并被选为取代从Cobre Advisee身份毕业的人。中心 还将对活动，项目领导者及其研究，科学进行系统，客观的评估 建议和教师发展计划以及核心功能。该策略将确保长期成功 该中心是一个独立但整合的调查单位，在校园内，充满活力和协同作用 全面解决癌症的短期和长期副作用的研究环境 治疗。