Social determinants of cardiovascular disease risk over the life course

生命历程中心血管疾病风险的社会决定因素

• 批准号: 10483129
• 负责人: ANA V DIEZ-ROUX
• 金额: $ 24.62万
• 依托单位: DREXEL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10483129
• 关键词: Americas; Applications Grants; Cardiovascular Diseases; Central America; Central American; Cities; Collaborations; Communities; Country; Data Analytics; Development; Doctor' s Degree; Educational workshop; Elements; Faculty; Healthcare; Healthcare Systems; Incidence; Income; Information Dissemination; Institutes; Interdisciplinary Study; Intervention; Journals; Lead; Life Cycle Stages; Life course epidemiology; Longevity; Master' s Degree; Mentors; Mentorship; Methods; Neighborhoods; Panama; Periodicity; Persons; Phase; Policies; Policy Maker; Postdoctoral Fellow; Prevalence; Public Health; Public Policy; Publications; Research; Research Methodology; Research Personnel; Risk Factors; Site; Students; Training; Training Activity; Training Programs; Translational Research; Translations; Universities; Urbanization; Visit; base; cardiovascular disorder risk; data management; doctoral student; interdisciplinary approach; mid-career faculty; nutrition; prevent; programs; research data dissemination; social; social determinants; social health determinants; social influence; webinar

PROJECT SUMMARY Over the last several decades, cardiovascular disease (CVD) incidence and the prevalence of CVD risk factors have steadily increased in the Central American region, in contrast to other countries of the Americas where CVD is no longer increasing or on the decline. The rise of CVD in the region has occurred in tandem with increases in urbanization and widening social inequities, and poses a growing, untenable burden for its limited public health and health care systems. While research in high income countries highlights interventions on social determinants of health as levers to prevent cardiovascular disease, less is known about the specific, intervenable social determinants that can help prevent CVD in Central America. Training and mentoring of the local workforce in identifying relevant research questions, in the use of appropriate research methods, and in the dissemination of results to the scientific community, the public, and policy makers is critical to identify and develop interventions to prevent CVD in the region. To this end, researchers from Drexel University and the Institute for Nutrition of Central America and Panama (INCAP) have partnered to establish a training program focused on developing the research capabilities of trainees and local capacity building in the conduct of policy- relevant research on the influence of social determinants and place-based factors on CVD risk across the lifespan. Key elements include: (1) a focus on factors at multiple levels (from cities, to neighborhoods, to persons) and over the lifecourse, (2) the use of rigorous state-of-the-art methods; (3) an emphasis on the value of interdisciplinary approaches; and (4) dissemination and translation of research findings into policy actions. The program leverages the SALURBAL Study, a unique multidisciplinary collaboration focused on the region. Training activities will include (1) training of up to 3 PhD students or up to 5 Masters students; (2) support for up to 4 postdoctoral fellows and 11 visiting faculty fellows promoting the development of junior and mid-career faculty; (3) annual workshops and periodic webinars and journal clubs on social determinants of health, CVD and lifecourse epidemiology, and research methods; (4) support for the development of data management and analytical capacity on site; and (5) enhanced south-south collaborations in mentorship and research. As a result of the program we expect to see an increase in the number researchers with Masters or Doctoral degrees at INCAP, an increase in the number of publications and grant proposals submitted by local researchers, larger numbers of mentoring relationships, publications, and grant proposals involving collaborations between INCAP and other countries in the region, greater capacity for data management/analysis at INCAP, and greater engagement of local investigators in CVD research and dissemination activities, including policy translation in the region. We also expect to see a continuation proposal to this training program submitted by INCAP as lead at the end of the this initial phase of the program.

项目摘要 在过去的几十年中，心血管疾病（CVD）发病率和CVD风险因素的患病率 与美洲其他国家相比，中美洲地区稳步增长 CVD不再增加或下降。该地区CVD的兴起与 城市化和扩大社会不平等的增加，并为其有限 公共卫生和卫生保健系统。高收入国家的研究强调了干预措施 健康的社会决定因素是预防心血管疾病的杠杆，对特定的特定知之甚少， 可以帮助预防中美洲CVD的可理解社会决定因素。培训和指导 当地劳动力在识别相关研究问题，使用适当的研究方法以及 将结果传播给科学界，公众和政策制定者对于识别和 制定干预措施以防止该地区的CVD。为此，Drexel大学和 中美洲和巴拿马营养研究所（INCAP）已合作建立培训计划 专注于发展受训者和地方能力建设的研究能力，以进行政策 - 关于社会决定因素和基于地点因素对CVD风险影响的相关研究 寿命。关键要素包括：（1）关注多个级别的因素（从城市到社区，再到 人）和生命之后，（2）使用严格的最先进方法； （3）强调价值 跨学科方法； （4）将研究结果传播和翻译为政策行动。 该计划利用了Salurbal研究，这是一个独特的多学科合作，重点是该地区。 培训活动将包括（1）最多3位博士生或最多5名硕士学生的培训； （2）支持 多达4个博士后研究员和11名参观教职员工，促进了初中和职业生涯的发展 学院; （3）年度研讨会和周期性网络研讨会和新闻社会决定因素，CVD 和生命的流行病学和研究方法； （4）支持数据管理和 现场分析能力； （5）增强了指导和研究方面的南南合作。作为 该计划的结果我们希望看到硕士或博士学位的研究人员的数量有所增加 Invap时学位，出版物数量增加和当地提交的赠款提案 研究人员，大量的指导关系，出版物和批准提案 不合格与该地区其他国家之间的合作，数据能力更大 裁员时的管理/分析，以及当地研究人员参与CVD研究和 传播活动，包括该地区的政策翻译。我们还希望看到一个延续 该培训计划提交的建议在该计划的初始阶段结束时提交了作为潜在客户的提议。