Developmental Research Program

发展研究计划

• 批准号: 10478823
• 负责人: Sarki A. Abdulkadir
• 金额: $ 24.13万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-18 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10478823
• 关键词: Area; Chicago; Clinic; Development; Developmental Process; Ensure; Funding; Goals; Health system; Leadership; Malignant neoplasm of prostate; Mission; Monitor; Peer Review; Pilot Projects; Process; Progress Reports; Prostate; Request for Applications; Research; Research Personnel; Review Committee; Secure; Structure; System; Translating; United States National Institutes of Health; Universities; Woman; advanced prostate cancer; anticancer research; base; flexibility; innovation; insight; interest; medical schools; meetings; member; minority investigator; programs; recruit; translational potential; web site

DEVELOPMENTAL RESEARCH PROGRAM (DRP): ABSTRACT The Developmental Research Program (DRP) is an essential component of the Prostate SPORE, providing yearly funding to 4-6 projects that are peer reviewed and deemed to have promising translational potential. Funding is flexible, supporting projects for a period of two years or less. It is expected that DRP investigators will develop and advance their pilots sufficiently to either replace main projects that are not progressing or will secure independent funding in prostate cancer research. Of note, all three projects presented in the renewal have emanated from pilot projects and propose translating discoveries made in the investigators’ labs to the clinic. The DRP follows a highly structured process to solicit projects from investigators who are interested in developing projects in the area of prostate cancer, to review projects according to NIH review criteria and to monitor projects for scientific progress. The DRP is maintained throughout the entire period of SPORE funding. The specific aims of the Developmental Research Program are: • Specific Aim 1: To solicit, review and select innovative and translational pilot projects through the highly structured process. A request for applications (RFA) is sent out to investigators at the Northwestern University (NU), University of Chicago and its affiliated NorthShore University HealthSystems. The Scientific Review Committee reviews pilot projects based on the quality and importance to the overall SPORE mission. • Specific Aim 2: To monitor progress of pilot projects within the context of the overall SPORE goals. Pilot project investigators are required to present their results twice per year at SPORE investigators meeting. They also meet twice per year with the Directors of the DRP to obtain translational insight and to ensure that scientific milestones are being achieved. DRP investigators are required to submit a written progress report that is rigorously evaluated by the SPORE PI and members of the Executive Committee. • Specific Aim 3: To encourage and recruit additional investigators to pursue research in prostate cancer through a SPORE web site and by widely distributing the RFA announcing the availability of funds. Women and minority investigators are strongly encouraged to submit pilot projects. • Specific Aim 4: To maintain the administrative process for the Developmental Research Program throughout the SPORE funding period.

发展研究计划 (DRP)：摘要 发展研究计划 (DRP) 是前列腺 SPORE 的重要组成部分，提供 每年资助 4-6 个经过同行评审并被认为具有良好转化潜力的项目。 资金是灵活的，支持项目的期限预计为两年或更短。 将充分开发和推进试点项目，以取代没有进展或将要进行的主要项目 值得注意的是，续订中提出了所有三个项目。 来自试点项目，并建议将研究人员实验室的发现转化为 DRP 遵循高度结构化的流程来向感兴趣的研究人员征集项目。 开发前列腺癌领域的项目，根据 NIH 审查标准审查项目并 DRP 在 SPORE 资助的整个期间都得到维护。 发展研究计划的具体目标是： • 具体目标1：通过高度重视，征求、审查和选择创新性和转化性试点项目。 向西北大学的研究人员发送申请请求 (RFA)。 （NU）、芝加哥大学及其附属的北岸大学健康系统。 委员会根据 SPORE 整体任务的质量和重要性来审查试点项目。 • 具体目标2：在SPORE 试点项目总体目标的背景下监测试点项目的进展情况。 调查人员每年必须在 SPORE 调查人员会议上提交两次结果。 每年与 DRP 主任会面两次，以获得转化见解并确保科学 DRP 调查人员必须提交书面进度报告，以实现里程碑。 由 SPORE PI 和执行委员会成员严格评估。 • 具体目标 3：鼓励和招募更多研究人员通过以下方式开展前列腺癌研究： SPORE 网站并广泛分发 RFA，宣布向妇女和少数族裔提供资金。 强烈鼓励研究人员提交试点项目。 • 具体目标 4：在整个过程中维持发展研究计划的管理流程 SPORE资助期。