African American Families Fighting Parental Cancer Together

非裔美国家庭共同抗击父母癌症

基本信息

批准号：
10478019
负责人：
ADAM DAVEY
金额：
$ 35.45万
依托单位：
UNIVERSITY OF DELAWARE
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-07-01 至 2024-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10478019
关键词：
Address Adolescent Adult African American African American population Aftercare Age Anxiety Attitude Behavior Black race Breast Cancer Center Cancer Etiology Cancer Patient Caucasians Child Child Rearing Clinical Cognition Colon Colorectal Communication Cultural Sensitivity Depressed mood Development Diagnosis Diagnostic Neoplasm Staging Distress Emotional Ethnic group Family Gender Home Illness impact Income Intention Intervention Life Low income Lung Malignant Neoplasms Marital Status Mediating Mission Nature Newly Diagnosed Not Hispanic or Latino Outcome Parent-Child Relations Parental Ages Parents Participant Patients Population Population Intervention Prevention program Prostate Race Randomized Randomized Controlled Trials Research Sampling School-Age Population Socioeconomic Status Solid Neoplasm Stress Support Groups Time United States Vulnerable Populations Youth base cancer health disparity child depression comparative efficacy coping daily functioning depressive symptoms design efficacy evaluation emotional distress experience fighting follow-up high risk improved improved outcome inner city intervention program psychoeducation psychoeducational intervention public health relevance recruit stressor treatment as usual treatment effect

项目摘要

DESCRIPTION (provided by applicant): In 2015, an estimated 340,000 parents of school age children will be newly diagnosed with cancer in the U.S. Parental cancer causes significant emotional distress in both diagnosed parents and children. African American (AA) adults experience a disproportionate burden of solid tumor cancers (e.g., breast, prostate, lung, and colon) which puts AA adolescents, a vulnerable population to begin with, at high risk for parental cancer related distress. Treatments have been somewhat successful for younger school age children (ages 7-12) of cancer patients but most treatment studies have included white middle class samples. Differences in attitudes, daily functioning and levels of distress among different ethnic and racial groups are well-documented, yet few culturally sensitive family intervention programs have been developed for AA families coping with cancer. Building on the PI's previous studies with AA families coping with parental cancer, we propose to conduct a randomized control trial to address this gap. We will of a culturally sensitive family-based intervention that targets the parent child relationship in AA families coping with the impact of solid tumor parental cancer. We will randomize 172 AA families coping with parental cancer to either Families Fighting Cancer Together (FFCT) or to parent psycho-education (TAU). Both manualized treatments include 5 bi-monthly sessions over 10 weeks. Subjects will be African American parents diagnosed for the first time in the past 12 months with Stage I, II, or III solid tumor cancers with at least one child between the ages of 12 and 18 living at home. Patients will be recruited from 3 large inner city cancer centers where there is an estimated 500 eligible low to middle income AA cancer patients a year. Family assessments will be done at baseline, post-treatment (10 weeks), 6-month, and 12-month follow-up. The proposed R01 research has the following aims: Aim 1: Compare the efficacy of FFCT to TAU in reducing depressive symptoms (CDI) and anxiety (RCMAS) in AA adolescents at post-treatment and long term outcome (6 and 12-month follow-up). Aim 2: Compare the efficacy of FFCT to TAU in reducing parental stress (PCQ: impact of illness on child/concerns about parenting) in AA parents at post-treatment and long term outcome (6 and 12-month follow-up). Exploratory Aims: 1. Explore whether moderators identified in Caucasian samples have a similar impact on treatment in AA samples. Specifically, we will examine: a) perceived level of group support, b) gender and age of adolescent, c) parent's marital status, d) SES, and e) stage of parent's cancer on the impact of treatment. 2. Explore whether changes in parent-child attachment and communication mediate the association between treatment and depressive symptoms (CDI) and anxiety (RCMAS) at 6 and12-month follow-up. Treatments to help adolescents cope with the impact of parental cancer are urgently needed, particularly those designed to reach low-income AA populations. Developing effective and transportable family-based interventions for this population could improve developmental adjustment to this significant life stressor at a critical point in the livesof adolescents.

描述（由适用提供）：2015年，估计有34万学龄儿童的父母将在美国的父母癌症中新诊断出患有癌症，在被诊断的父母和孩子中造成严重的情绪困扰。非裔美国人（AA）成年人经历了实体瘤癌症（例如乳房，前列腺，肺和结肠）的伯恩伯嫩（Burnen），这使AA青少年（首先）以高风险与父母的癌症相关困扰。治疗是癌症患者的年轻儿童（7-12岁）的成功，但大多数治疗研究包括白人中产阶级样本。不同种族和种族群体之间的出勤差异，日常运作和困扰水平是有据可查的，但很少有文化敏感的家庭干预计划为应对癌症的AA家庭制定了敏感的家庭干预计划。在PI先前与AA家族应对父母癌症的研究的基础上，我们建议进行一项随机对照试验以解决这一差距。我们将进行基于文化敏感的家庭干预措施针对AA家庭中的父母关系应对实体瘤的影响癌症。我们将将应对父母癌的172个AA家族随机分配给与癌症作斗争（FFCT）或父母心理教育（TAU）的家庭。两种手动治疗都包括在10周内进行5个月的5个月疗程。受试者将是过去12个月中首次被诊断出的非洲裔美国父母，其中I，II或III次实体瘤癌症至少有一个12至18岁的孩子在家中。患者将从3个大型内城癌症中心招募，估计有500名合格的低至中收入为中心癌症患者。家庭评估将在基线，治疗后（10周），6个月和12个月的随访中进行。拟议的R01研究具有以下目的：目标1：比较FFCT在减少抑郁症状（CDI）和焦虑症（RCMAS）中的效率（在治疗后和长期结局（6和12个月的随访）中）。目标2：比较FFCT在减少父母压力（PCQ：疾病对儿童/对育儿的影响的影响）在治疗后父母和长期结果（6和12个月的随访）中的效率。探索目的：1。探索在高加索样品中鉴定出的主持人是否对AA样品中的治疗有类似的影响。具体而言，我们将研究：a）感知的群体支持水平，b）青少年的性别和年龄，c）父母的婚姻状况，d）SES和e）父母癌症对治疗影响的阶段。 2。探索在6和12个月的随访中，是否会发生变化，是否会发生变化。迫切需要治疗以帮助青少年应对父母癌的影响，尤其是那些旨在达到低收入AA人群的治疗方法。为该人群开发有效且可运输的基于家庭的干预措施可以改善对青少年生命的关键点的重要生命压力源的发展调整。

项目成果

期刊论文数量（13）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Study protocol: a randomized control trial of African American families fighting parental cancer together.

DOI：
10.1186/s12885-018-5052-8
发表时间：
2018-11-20
期刊：
BMC cancer
影响因子：
3.8
作者：
McKinney NS;Virtue S;Lewis FM;Willis AI;Pettyjohn T;Harmon LR;Davey A
通讯作者：
Davey A

Carotid Artery Blood Flow Velocities and Cognitive Performance: Forecasting Cognitive Decline.

颈动脉血流速度和认知表现：预测认知能力下降。

DOI：
10.1093/ajh/hpy184
发表时间：
2019
期刊：
American journal of hypertension
影响因子：
3.2
作者：
Elias,MerrillF;Torres,RachaelV;Davey,Adam
通讯作者：
Davey,Adam

Frailty in community-dwelling older people and nursing home residents: An adaptation and validation study.

社区老年人和疗养院居民的虚弱：一项适应和验证研究。

DOI：
10.1111/jan.15898
发表时间：
2024
期刊：
Journal of advanced nursing
影响因子：
3.8
作者：
Kmetec,Sergej;Fekonja,Zvonka;Davey,Adam;Kegl,Barbara;Mori,Jernej;Reljić,NatašaMlinar;McCormack,Brendan;Lorber,Mateja
通讯作者：
Lorber,Mateja

Development of a slovenian version of the pittsburgh sleep quality index (PSQI-SLO) for use with older adults.