Support for Graduate, PDF and New Faculty Presenters at the 2022 American Society of Pharmacognosy Meeting

为 2022 年美国生药学会会议上的研究生、PDF 和新教师演讲者提供支持

• 批准号: 10469168
• 负责人: Mark T Hamann
• 金额: $ 3万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10469168
• 关键词: 2019-nCoV; Address; Agriculture; American; Area; Back; Beauty; Biology; Caliber; Cancer Control; Carbon Dioxide; Chemicals; Clinical Research; Collaborations; Communities; Complementary Medicine; Core Facility; Country; Cryoelectron Microscopy; Development; Dictionary; Disease; Dyes; Education; Educational workshop; Emerging Communicable Diseases; Environment; Environmental Science; Equilibrium; Event; Faculty; Fees; Fostering; Funding; Future; Goals; Health; Historically Black Colleges and Universities; Human; Institution; Island; Knowledge; Laboratories; Marine Biology; Medical; Medicine; Methods; Mission; Movement; Municipalities; National Center for Complementary and Integrative Health; National Oceanic and Atmospheric Administration; Natural History; Natural Products; Nature; Oils; Petroleum; Pharmaceutical Preparations; Pharmacognosy; Pharmacologic Substance; Photosynthesis; Plants; Play; Population Heterogeneity; Postdoctoral Fellow; Production; Recording of previous events; Research; Research Personnel; Role; Science; Scientist; Social Interaction; Societies; Source; South Carolina; Southeastern United States; Standardization; Students; Techniques; Therapeutic; Therapeutic Agents; Training; Training and Education; Travel; Underrepresented Populations; United States National Institutes of Health; Universities; Women' s Group; Work; base; career; career development; college; consumer product; drug development; drug discovery; global health; graduate student; improved; indigo dye; innovation; instrument; interest; medical schools; meetings; member; men' s group; neglect; nervous system disorder; next generation; outreach; programs; prototype; recruit; small molecule; social; student mentoring; symposium; synthetic biology; translational study

PROJECT SUMMARY/ABSTRACT Natural products have provided humankind the key starting materials to support health by providing therapeutic agents and structural templates for medicinal chemists. The field of natural products is rapidly evolving to fill anticipated supply gaps due to the movement away from petroleum based energy, fine chemicals and pharmaceuticals. Although only about 1% of every barrel of oil is used in the manufacture of pharmaceutical products it is estimated petroleum supplies 99% of the starting materials for pharmaceutical and other consumer products. Thus one of three key Aims of this meeting includes the replacement of petroleum based starting materials for therapeutics with natural products. A second key aim for this meeting is an assessment of panomics approaches to the discovery and development of natural product prototypes for the control of cancer and emerging infectious diseases, including SARS-CoV2. Emerging methods involving CryoEM in drug discovery and development will be featured at this meeting. The need for better controls for emerging infectious diseases needs no explanation; however; the role of natural products as critical starting materials and new prototypes will be addressed as part of the 2022 American Society of Pharmacognosy Conference. Finally, a third key aim of the program is to assess the role that natural products and natural products investigators can play in controlling carbon dioxide levels in the environment. This can take the form of photosynthesis of agriculture or direct conversion of CO2 into the starting materials for pharmaceuticals and other consumer products. We fully anticipate that NPs will serve the needs of human health in regard to new prototypes well into the future. This conference will showcase many aspects of these emerging needs with cutting-edge approaches that are moving the field forward at an accelerated pace. We have selected leaders in the field as conference chairs and speakers that align well with the mission of the NCCIH including a significant number of speakers with expertise in analytical techniques for evaluating and standardizing materials used as complementary medicines. This project seeks funding to support the American Society of Pharmacognosy (ASP) meeting that will be held July 23-28th in Charleston, SC. The ASP is the largest society in the USA that focuses on natural products. The ASP as well as this conference focuses on molecules from nature and their application to improve human health. Support from the NIH will help offset registration fees and assist with travel for students and new faculty from the US and US Territories with a focus on regional HBCUs (historically black colleges and universities) of the South Eastern US. Thus our final aim is to train the next generation of scientists through the recruitment and support attendees from the PUIs with a focus on the Southeastern US.

项目摘要/摘要 天然产品为人类提供了通过提供治疗的关键起始材料来支持健康 药物化学家的试剂和结构模板。天然产品领域正在迅速发展以填充 预期的供应差距由于从石油的能量，精细化学物质和 药品。尽管每桶油中只有大约1％用于制造药物 产品估计，石油为药品和其他消费者提供了99％的起始材料 产品。因此，这次会议的三个关键目标之一包括替换基于石油的启动 天然产品治疗材料。这次会议的第二个关键目的是评估Panomics 发现和开发自然产品原型的方法，以控制癌症和 包括SARS-COV2在内的新兴传染病。涉及冷冻在药物发现中的新兴方法 开发将在这次会议上展出。需要更好地控制新兴的传染病 不需要解释；然而;天然产品作为关键起始材料和新原型的作用将 作为2022年美国药学学会会议的一部分。最后，是第三个关键目标 该计划是评估天然产品和天然产品调查人员可以在控制中发挥的作用 环境中的二氧化碳水平。这可以采用农业光合作用的形式或直接 将二氧化碳转换为药品和其他消费产品的起始材料。我们完全 预计NP将在未来的新原型方面满足人类健康的需求。这 会议将通过移动的尖端方法展示这些新兴需求的许多方面 该领域以加速的速度向前。我们选择了该领域的领导者作为会议主席和演讲者 这与NCCIH的使命非常吻合，包括大量具有专业知识的发言人 用于评估和标准化材料的分析技术。这个项目 寻求资金来支持将于7月23日至28日举行的美国药学学会（ASP）会议 在南卡罗来纳州查尔斯顿。 ASP是美国最大的社会，专注于天然产品。 ASP也 由于这次会议的重点是自然的分子及其用于改善人类健康的应用。支持 NIH将有助于抵消注册费，并为来自美国的学生和新教师提供旅行 美国领土，重点关注东南部地区的区域HBCU（历史悠久的黑人学院） 我们。因此，我们的最终目标是通过招聘和支持与会者培训下一代科学家 从Puis开始，重点是美国东南部。