7th GenTAC Thoracic Aortic Disease Summit

第七届 GenTAC 胸主动脉疾病峰会

基本信息

批准号：
10462853
负责人：
Kim Eagle
金额：
$ 2.54万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-04-01 至 2023-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10462853
关键词：
Acute Aortic Diseases Award Basic Science Belgium Blood Vessels COVID-19 pandemic Cardiovascular system Chest China Clinical Clinical Sciences Collaborations Communication Eagles Engineering Enrollment European Faculty Foundations Funding Germany Grant Heart International Italy Japan Location Marfan Syndrome Michigan Mission National Heart, Lung, and Blood Institute National Institute of Arthritis and Musculoskeletal and Skin Diseases Netherlands Paris, France Participant Patient Care Patients Physician Executives Principal Investigator Registries Research Research Personnel Scientist Spain Structure Syndrome Thoracic Aortic Aneurysm Time Translational Research Travel Turner&apos s Syndrome Underrepresented Minority Universities Walking Woman bicuspid aortic valve career design experience improved lectures meetings mid-career faculty multidisciplinary novel posters programs social symposium synergism virtual

项目摘要

This application is in request for support for the 7th GenTAC Thoracic Aortic Disease Summit to be held in Paris, France on April 28, 2022. This unique meeting brings together multidisciplinary groups of clinicians, scientists, and engineers to advance our understanding of the underlying mechanisms of thoracic aortic disease and to improve our ability to treat those who are afflicted by these conditions, which includes both young and old. The 7th GenTAC summit for the first time will be held in collaboration 11th International Research Symposium on Marfan Syndrome (held April 24-27 at the same location) and is organized jointly with the Marfan Foundation. This shared meetings provides a forum not only where ideas are shared and scrutinized, but new collaborations are born. The biannual GenTAC conference originated in 2009 as part of the mission of the National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Related Cardiovascular Conditions (GenTAC). GenTAC was funded by NHLBI and NIAMS and enrolled and followed over 3600 patients from 2006 through 2016. Gentac Alliance was initiated in 2017 to harness the synergy and collaboration created by the GenTAC. The 5th GenTAC Summit was held on Oct 6-7, 2018 at OHSU in Portland, OR and the 6th GenTAC Summit was held virtually due to the covid-19 pandemic on October 10/11 2020. The preliminary program for this 1-day GenTAC summit includes scientific sessions on (i) Familial Aortopathy, (ii) Bicuspid aortic valve, (iii) Turner Syndrome, and (iv) Acute aortic syndrome. There will be synergy with the program of the 11th Research Symposium on Marfan syndrome. We anticipate that clinicians and researcher will attend both meetings representing different groups in the field of thoracic aortic aneurysms including Marfan Foundation, IRAD, Montalcino Aortic Consortium, BAVCON, EDS-PCORI, Turners, and European Vascular Network are participating. We have >80% of invited speakers are confirmed. Participation of trainees and underrepresented minorities is especially encouraged by awarding 10 travel awards. The meeting is hosted by Marfan Foundation and the Frankel Cardiovascular Center at the University of Michigan. The core conference organization committee includes Dr. Marion A Hofmann Bowman and Dr. Kim Eagle as the principal investigators of this grant, and Dr. Josephine Grima from the Marfan Foundation. This team also successfully organized the 2020 6th GenTAC meeting. Kim A. Eagle is the Director of the Frankel Cardiovascular Center at the University of Michigan and the chair of the NHLBI sponsored GenTAC Alliance and he served as the study chair of the GenTAC registry from 2006-2016. Dr. Marion A Hofmann Bowman is a Clinical Associate Professor and Executive Medical Director of the MiAorta program at the University of Michigan. Her expertise is in clinical-translational research related to thoracic aortic disease.

本申请旨在为即将在北京举行的第七届 GenTAC 胸主动脉疾病峰会提供支持 2022 年 4 月 28 日在法国巴黎举行。这次独特的会议汇集了多学科临床医生小组，科学家和工程师促进我们对胸主动脉疾病潜在机制的理解并提高我们治疗受这些疾病困扰的人的能力，其中包括年轻人和儿童老的。第七届GenTAC峰会首次将联合第十一届国际研究研讨会举办关于马凡氏综合症（4 月 24 日至 27 日在同一地点举行），由与马凡基金会联合举办。这次共享会议不仅提供了一个分享和审查想法的论坛，而且还提供了新的合作出生了。一年两次的 GenTAC 会议起源于 2009 年，是国家登记处使命的一部分遗传触发的胸主动脉瘤和相关心血管疾病 (GenTAC)。 GenTAC 由 NHLBI 和 NIAMS 资助，从 2006 年到 2016 年招募并随访了 3600 多名患者。 Gentac 该联盟于 2017 年发起，旨在利用 GenTAC 创造的协同作用和协作。第五届GenTAC 峰会于 2018 年 10 月 6 日至 7 日在俄勒冈州波特兰市的 OHSU 举行，第六届 GenTAC 峰会以虚拟方式举行 2020 年 10 月 10 日发生的 covid-19 大流行。这次为期 1 天的 GenTAC 峰会的初步计划包括以下方面的科学会议：(i) 家族性主动脉病、 (ii) 二叶式主动脉瓣，(iii) 特纳综合征，以及 (iv) 急性主动脉综合征。将与以下机构产生协同效应第十一届马凡综合征研究研讨会计划。我们预计临床医生和研究人员将代表胸主动脉瘤领域的不同团体（包括马凡）参加这两次会议基金会、IRAD、蒙达奇诺主动脉联盟、BAVCON、EDS-PCORI、Turners 和欧洲血管协会网络参与。我们已经确认了超过 80% 的受邀演讲者。学员的参与和通过颁发 10 项旅行奖励，特别鼓励代表性不足的少数群体。本次会议由马凡基金会和英国大学弗兰克尔心血管中心主办密歇根州。核心会议组织委员会包括Marion A Hofmann Bowman博士和Kim博士 Eagle 是这项资助的主要研究者，还有来自马凡基金会的 Josephine Grima 博士。这团队还成功组织了2020年第六届GenTAC会议。 Kim A. Eagle 是 Frankel 的董事密歇根大学心血管中心和 NHLBI 赞助的 GenTAC 联盟主席 2006年至2016年间，他担任GenTAC注册中心的研究主席。 Marion A Hofmann Bowman 博士是英国大学 MiAorta 项目临床副教授兼执行医疗主任密歇根州。她的专长是与胸主动脉疾病相关的临床转化研究。