Global Health Catalyst (GHC) Summit

全球健康催化剂 (GHC) 峰会

• 批准号: 10460585
• 负责人: Stephen Avery
• 金额: $ 2万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-02 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10460585
• 关键词: Address; Advocacy; Africa; African; Area; Artificial Intelligence; Automobile Driving; Brain Drains; Cancer Burden; Cancer Control; Cancer Patient; Cessation of life; Collaborations; Country; Development; Education; Ensure; Evaluation; Faculty; Feedback; Fertility; Funding; Funding Opportunities; Goals; Growth; Health Professional; Healthcare; Human; Immigrant; Industry; Industry Collaboration; Information Technology; Institution; International; Intervention; Joints; Journals; Knowledge; Legal patent; Malignant Neoplasms; Mentors; Multi-Institutional Clinical Trial; Multimedia; Oncology; Outcome; Peer Review; Pennsylvania; Persons; Policies; Population; Professional Organizations; Publications; Publishing; Radiation Oncology; Radiation therapy; Reporting; Research; Research Personnel; Resources; Safety; Students; Technology; Training; Training and Education; Underrepresented Minority; United States; Universities; Work; World Health Organization; anticancer research; base; cancer care; cancer education; cancer health disparity; catalyst; cost effective; design; disorder prevention; education research; evidence base; experience; global health; improved; industry partner; innovation; interest; low and middle-income countries; outreach; overtreatment; programs; response; success; symposium; tool; virtual platform; web site

Project Summary Recently, leaders in cancer policy from the USA and 14 economically diverse countries concluded that successful campaigns to control cancer will increasingly depend on concerted international collaborations. The recent World Health Organization Cancer Report highlights urgency for such international collaborations, with over 60% of 14 million new cancer cases and 70% of 8.2 million deaths per year occurring in low and middle income countries (LMIC), some of which, sadly, are the least capable of dealing with cancer without some form of collaboration. These major disparities in cancer deaths are in part a reflection of poignant underlying disparities in Radiation Oncology. For example, radiotherapy, which is needed in the treatment of over 50% of cancer patients, is not available in about half of Africa's 54 countries, and preliminary research shows major safety concerns in implementation of radiotherapy where available. The overall goal of this proposal is to organize yearly global health catalyst (GHC) cancer summits designed to catalyze high impact international collaborations between US and African Institutions to address the growing global burden of cancers, and associated disparities. This GHC summits, will build on the success and lessons learned over the past years during previously organized summits, that have catalyzed collaborations to support cancer healthcare institutions in different African countries, supported education and training efforts to build human/research capacity, and established fecund research collaborations, along with disease prevention and advocacy programs in global oncology. An innovative component of the summit is the focus on outreach engagement of under-represented minorities and the resource-laden Africans in Diaspora (AiD) to turn the devastating effects of brain drain to gain against cancer. Outcomes will include: new and strengthened collaborations involving partners from both USA and African institutions each year, significant increase in participation of under-represented minorities and diaspora in global oncology, peer-reviewed publications co-authored by both USA and African collaborators, joint patents resulting from research collaborations, and continuous growth to engage more participation from USA and African Institutions to address the growing global burden of cancer and associated disparities.

项目摘要 最近，来自美国和14个经济多元化国家的癌症政策领导者得出了结论 成功控制癌症的运动将越来越依赖于协同的国际 协作。最近的世界卫生组织癌症报告强调了这种紧迫性 国际合作，有超过60％的新癌症病例中有60％，以及820万的70％ 低收入国家（LMIC）每年死亡，其中一些是可悲的是 没有某种形式的协作的能力最低的能力。这些专业 癌症死亡的差异部分反映了辐射的潜在差异 肿瘤学。例如，放射疗法在治疗超过50％的癌症时需要 患者在非洲54个国家中大约一半不可用，初步研究表明 可用的放射治疗实施的主要安全问题。总体目标 提案是组织年度全球健康催化剂（GHC）癌症峰会，旨在催化 美国与非洲机构之间的高影响国际合作，以解决 癌症的全球负担不断增长，以及相关的差距。这个GHC峰会将基于 在过去的几年中，在先前组织的峰会上学习的成功和经验教训， 已经催化合作以支持不同非洲的癌症医疗机构 国家，支持建立人/研究能力的教育和培训工作，以及 建立的Fecund研究合作以及疾病预防和倡导 全球肿瘤学计划。峰会的创新组成部分是关注外展 参与代表性不足的少数民族和散居侨民资源的非洲人（AID） 扭动大脑流失的毁灭性影响以抵抗癌症。结果将包括：新的 并加强了与美国和非洲机构的合作伙伴有关的合作 一年，代表性不足的少数群体和侨民的参与大幅增加 肿瘤学，由美国和非洲合作者共同撰写的同行评审出版物 研究合作和持续增长产生的专利以参与更多 美国和非洲机构的参与应对日益严重的癌症负担 和相关的差距。

项目成果

Challenges and opportunities for implementing hypofractionated radiotherapy in Africa: lessons from the HypoAfrica clinical trial.

• DOI: 10.3332/ecancer.2023.1508
• 发表时间: 2023
• 期刊: ECANCERMEDICALSCIENCE
• 影响因子: 1.8
• 作者: Olatunji, Elizabeth;Swanson, William;Patel, Saloni;Adeneye, Samuel Olaolu;Aina-Tofolari, Funmilayo;Avery, Stephen;Kisukari, Jumaa Dachi;Graef, Katy;Huq, Saiful;Jeraj, Robert;Joseph, Adedayo;Lehmann, Joerg;Li, Heng;Mallum, Abba;Mkhize, Thokozani;Ngoma, Twalib Athumani;Studen, Andrej;Wijesooriya, Krishni;Incrocci, Luca;Ngw, Wifered
• 通讯作者: Ngw, Wifered

Utilization of cancer immunotherapy in sub-Saharan Africa.

• DOI: 10.3389/fonc.2023.1266514
• 发表时间: 2023
• 期刊: Frontiers in oncology
• 影响因子: 4.7