Admin. Supp. for NCI P30 Cancer Center Grants to Facilitate the Development of Standardized Electronic Treatment Plan Builds for NCI-Supported Clinical Trials Applicable Across Clinical Research Sites

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• 批准号: 10442122
• 负责人: RAPHAEL E. POLLOCK
• 金额: $ 27.61万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-01-25 至 2025-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10442122
• 关键词: Amendment; Cancer Center; Cancer Center Support Grant; Caring; Charge; Clinical; Clinical Research; Clinical Trials; Clinical Trials Network; Comprehensive Cancer Center; Custom; Data; Data Collection; Data Element; Development; Diagnostic; Electronic Health Record; Ensure; Goals; Grant; Health Personnel; Immunotherapy; Indiana; Individual; Infrastructure; Institution; Insurance Carriers; Intervention; Investigation; Iowa; Logic; Michigan; Modification; Multi-Institutional Clinical Trial; National Clinical Trials Network; Ohio; Ontology; Patient Care Planning; Patients; Pharmacologic Substance; Play; Procedures; Process; Protocols documentation; Quality Control; Site; Standardization; Structure; System; Testing; Therapeutic; Third-Party Payer; Time; Translations; Universities; Validation; Vendor; anticancer research; base; cancer clinical trial; clinical research site; community center; cost; design; follow-up; innovation; intervention program; member; novel; patient population; prospective; ranpirnase; standard of care; syntax; tool; treatment planning

PROJECT SUMMARY Electronic health records (EHR) are used in all NCI-supported Cancer Centers. EHR data support not only the delivery of standard-of-care treatments, but also investigational diagnostic and interventional programs in clinical research. Although EHR-based care plans provide quality control for care processes, such as the administration of pharmaceuticals, these procedures vary extensively from one health care provider to another, even when the same EHR is used by both organizations. In supporting clinical trials with investigational agents, the electronic treatment plan is usually constructed from very basic data collection forms, regardless of whether a patient population is rare or common. Multi-institutional clinical trials require repeated efforts to modify different EHR systems present across potentially hundreds of institutions. The goal of this application is to create a consortium of Cancer Centers that will communicate and coordinate with the NCI and EHR vendors to facilitate and harmonize rapid implementation of EHR investigational or interventional treatment plans for NCTN clinical trials. The Ohio State University Comprehensive Cancer Center will participate in this BIG10- EHRC consortium project, which includes a Coordination Center at the Indiana University and five membership centers, including: The Ohio State University, University of Michigan, University of Iowa, Northwestern University, and Rutgers University within the Big 10 Cancer Research Consortium. The project has the following three specific aims: 1) To retrospectively analyze similarities and differences of EHR treatment plan design and implementation across the member institutions in the Big Ten; 2) To develop novel EHR treatment plan tool kits conducive to rapid opening of NCTN clinical trials; and 3) To prospectively validate EHR treatment plan implementation across Big Ten institutions.

项目摘要 电子健康记录（EHR）用于所有NCI支持的癌症中心。 EHR数据不仅支持 提供护理标准治疗，以及临床的研究诊断和介入计划 研究。尽管基于EHR的护理计划为护理过程提供了质量控制，例如政府 在药品中，这些程序从一个医疗保健提供者到另一个医疗保健提供者，即使 两个组织都使用了相同的EHR。在支持研究剂的临床试验中，电子 治疗计划通常是由非常基本的数据收集表构建的，无论患者是否是 人口很少见或普遍。多机构临床试验需要重复努力来修改不同的EHR 可能存在数百个机构的系统。此应用程序的目的是创建一个 将与NCI和EHR供应商进行交流和协调的癌症中心财团 促进和协调EHR研究或介入治疗计划的快速实施 用于NCTN临床试验。俄亥俄州立大学综合癌症中心将参加这个Big10- EHRC财团项目，其中包括印第安纳大学的协调中心和五个会员资格 中心，包括：俄亥俄州立大学，密歇根大学，爱荷华大学，西北大学， 和罗格斯大学（Rutgers University）的十大癌症研究财团内。该项目具有以下三个 具体目的：1）回顾性分析EHR治疗计划设计的相似性和差异 十大成员机构之间的实施； 2）开发新颖的EHR治疗计划工具套件 有利于快速开放NCTN临床试验； 3）前瞻性验证EHR治疗计划 十大机构实施。