The Center for Accelerating Suicide Prevention in Real-world Settings (ASPIRES)

现实世界中加速预防自杀中心 (ASPIRES)

基本信息

批准号：
10436043
负责人：
JEFFREY A BRIDGE
金额：
$ 285.84万
依托单位：
RESEARCH INST NATIONWIDE CHILDREN'S HOSP
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-08-01 至 2027-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10436043
关键词：
Acute Address Adolescent Back Caring Child Childhood Clinical Pathways Common Data Element Communities Continuity of Patient Care Detection Development Discipline Early identification Effectiveness of Interventions Ensure Evidence based intervention Evidence based treatment Family Fostering Goals Grant Health Services Health Services Accessibility Healthcare Healthcare Systems Hospitalization Household Hybrids Implementation readiness Individual Infrastructure Inpatients Intervention Location National Institute of Mental Health Ohio Patients Pattern Pediatric Hospitals Persons Pilot Projects Plant Roots Population Heterogeneity Positioning Attribute Practice based research Prevention Prevention Research Prevention strategy Psychiatric Hospitals Public Health Recommendation Research Research Methodology Research Project Grants Risk Running Schools Science Service setting Suicide Suicide prevention Target Populations Technology Testing Translations Underserved Population United States Vision Work Youth acute care alternative treatment base brief intervention cohesion data integration data sharing effective intervention effective therapy effectiveness implementation design effectiveness implementation study effectiveness testing epidemiology study experience health care delivery health care settings health disparity high risk implementation context implementation facilitators implementation framework implementation strategy improved innovation medical specialties next generation point of care preventive intervention primary care setting programs reducing suicide research study routine practice screening socioeconomics suicidal adolescent suicidal behavior suicidal risk suicide rate synergism uptake

项目摘要

Suicide is a major and growing public health problem among youth in the United States. Integrating suicide prevention strategies as a core component of health care delivery and providing access to health services for individuals at risk for suicide is a primary goal of the National Action Alliance for Suicide Prevention (NAASP). Lack of prevention strategies universally assimilated into routine health care is an obstacle to achieving meaningful reductions in youth suicide. To address this problem, we propose to develop the Center for Accelerating Suicide Prevention in Real-world Settings (ASPIRES) to hasten the implementation of effective and scalable evidence-based interventions to reduce youth suicide. ASPIRES will focus on integrated programs of research that span the continuum of care from early identification in primary and specialty health care settings, to acute and transitional care, and back into the community as part of routine health care practice. The target population is youth at elevated risk for suicide, the majority of which are from lower socioeconomic households experiencing significant health disparities. The specific aims of ASPIRES include: (1) Create an infrastructure to foster innovative, transdisciplinary approaches to accelerate the implementation and utility of youth suicide prevention interventions in real-world settings; (2) Conduct integrated programs of high-impact research to improve risk detection and deploy innovative interventions that have strong potential for scalability and sustainability in real-world settings; (3) Characterize the implementation context to generate recommendations for contextually sensitive implementation strategies for varied healthcare settings; (4) Cultivate the next generation of emerging and advanced scholars from diverse backgrounds to conduct state- of-the-art suicide prevention research; (5) Coordinate a program of pilot studies that test the most promising ideas to accelerate innovations in practice-based youth suicide prevention; and (6) Communicate and disseminate center-related findings to key stakeholders and promote data sharing. The center’s planned portfolio of science includes integrated efforts promoting accelerated research across a continuum of health care settings that could not be accomplished using individual project mechanisms. The signature (R01-level) hybrid effectiveness-implementation project focuses on universal suicide risk screening and enhancing quality improvement in pediatric primary care settings. Three exploratory projects include: 1) testing an established intervention in a specialty care setting to address young children at high familial risk for suicidal behavior; 2) testing an evidence-based treatment alternative to inpatient hospitalization that targets family functioning to reduce youth suicidal behavior in an acute care setting; and 3) developing a technology-based intervention to promote lethal means restriction during the “high-risk” transitional care period following discharge from a psychiatric hospital. The project team is well-suited to run the proposed center with expertise from multiple disciplines and an extensive community-based stakeholder and patient network.

自杀是美国青年的一个重大公共卫生问题。整合自杀预防策略是医疗保健提供的核心组成部分，并为您提供卫生服务的机会有自杀风险的个人是国家预防自杀行动联盟（NAASP）的主要目标。缺乏普遍吸收常规医疗保健的预防策略是实现的障碍青年自杀的有意义减少。为了解决这个问题，我们建议开发在现实世界中加速自杀（志向），以实施有效以及可扩展的基于证据的干预措施，以减少青年自杀。愿望将集中于综合从初级和专业健康的早期识别中跨越护理的研究计划护理环境，急性和过渡护理，并作为常规医疗保健的一部分回到社区实践。目标人群是年轻人的自杀风险较高，其中大多数来自较低社会经济家庭遇到重大健康差异。志向的具体目标包括：（1）创建一个基础架构来促进创新的跨学科方法以加速实施以及在现实世界中预防青年自杀的效用；（2）进行集成程序高影响力的研究以改善风险检测和部署具有强大潜力的创新干预措施在现实环境中的可伸缩性和可持续性；（3）表征生成的实现上下文针对各种医疗机构的上下文敏感实施策略的建议；（4）培养来自潜水员背景的下一代新兴学者和高级学者，以进行状态 - 艺术自杀预防研究；（5）协调一个试验研究计划，该计划测试最承诺的在基于实践的青年预防自杀中加速创新的想法；（6）交流和将与中心相关的发现传播给主要利益相关者并促进数据共享。该中心的计划科学作品集包括综合努力促进健康连续性的加速研究无法使用单个项目机制来完成的护理设置。签名（R01级）混合有效性实施项目的重点是普遍自杀风险筛查和提高质量小儿初级保健环境的改善。三个探索性项目包括：1）测试已建立的干预专业护理环境，以解决具有自杀行为的高家族风险的幼儿； 2）测试一种基于证据的治疗替代住院住院的替代方法在急性护理环境中减少青年自杀行为； 3）开发基于技术的干预措施促进致命平均限制在出院后的“高风险”过渡期间精神病医院。项目团队非常适合以多个的专业知识来管理拟议的中心学科以及广泛的基于社区的利益相关者和患者网络。