Impact of Reduced Cannabis Use on Functional Outcomes

减少大麻使用对功能结果的影响

基本信息

批准号：
10437223
负责人：
JEAN C. BECKHAM
金额：
$ 16.08万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-20 至 2022-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10437223
关键词：
Abstinence Accidents Address African American American Behavior Behavior Therapy Cannabis Chronic Clinical Clinical Trials Data Data Collection Development Discrimination Ecological momentary assessment Epidemiology Exposure to Frequencies Health Illicit Drugs Impulsivity Intervention Laboratories Lead Literature Measures Memory Mental Health Methods Neuropsychology Outcome Outcome Measure Participant Persons Pharmacotherapy Phase Physical activity Prospective Studies Protocols documentation Public Health Race Reporting Research Risk Sampling Self Efficacy Short-Term Memory Sleep Substance Use Disorder Symptoms Techniques Technology Technology Assessment Testing Time Traffic accidents Underrepresented Populations Unemployment United States addiction contingency management craving drugged driving experience functional outcomes health related quality of life illicit drug use marijuana use marijuana use disorder marijuana user mobile computing negative affect non-suicidal self injury novel strategies parent grant parent project perceived stress physical conditioning portability psychological distress racial discrimination sex suicidal

项目摘要

Cannabis Use Disorder (CUD) is associated with a many negative functional outcomes, and unfortunately rates of CUD are increasing in the United States. More than 8 million Americans reported heavy cannabis use in 2013, representing a 59% increase since 2005. Heavy cannabis use (i.e., use on ≥ 40 of last 90 days) is associated with addiction, unemployment, neuropsychological deficits, lower educational attainment, and reduced physical activity. As shown across multiple epidemiologic samples, Black Americans are more likely to misuse cannabis than other racial groups. Heavy cannabis use has increased at an even higher rate among Black Americans. Racial discrimination remains a persistent and significant public health concern, undermining the health of underrepresented groups living in the USA and may be related to inequities in cannabis use and CUD. Racial discrimination is defined as unfair, differential treatment on the basis of race. There is a robust association between the experience of racial discrimination and psychological distress. Current evidence indicate that repeated everyday racial hassles are also associated with psychological distress and physical health. Persons who use cannabis to cope with negative affect are at increased risk of developing CUD. Currently, limited data exist examining the relationship between perceived discrimination and cannabis use outcomes although several recent studies suggest perceived stress and discrimination may be important determinants of cannabis use trajectories. These studies are limited, however, by a reliance on retrospective reports of perceived exposure to discrimination. We propose to supplement our parent project and state-of-the-art ecological momentary assessment (EMA) protocol with multiple measures of perceived discrimination to 1) Evaluate whether exposure to chronic discrimination is related to a) reported cannabis-related problems b) ad lib cannabis use in grams and b) magnitude of cannabis reduction during a four-week intervention period, and 2) Use ecological momentary assessment (EMA) technology to measure the daily association between perceived discrimination and cannabis use. Our central hypothesis for the proposed supplement is that experiences of discrimination and daily perceived unfair treatment will be related to cannabis use outcomes. The rationale for this research is that it will provide the first and only real-time data on this important, but understudied topic. Thus, our findings will directly inform our understanding regarding the effects of past and ongoing racial discrimination on cannabis use and misuse.

大麻使用障碍 (CUD) 与许多负面的功能结果相关，不幸的是美国的 CUD 发病率正在上升，超过 800 万美国人报告吸食大量大麻。 2013 年使用大麻，自 2005 年以来增加了 59%。大量使用大麻（即过去 90 次中 ≥ 40 次使用大麻）天）与成瘾、失业、神经心理缺陷、教育水平较低有关正如多个流行病学样本所示，黑人。与其他种族群体相比，美国人滥用大麻的可能性更大。美国黑人中的种族歧视比例更高。公共卫生问题，损害了居住在美国的代表性不足群体的健康，并可能与大麻使用和 CUD 方面的不平等有关的种族歧视被定义为不公平、差别待遇。基于种族的治疗种族经历之间存在密切关联。目前的证据表明，日常种族纠纷不断发生。也与使用大麻来应对心理困扰和身体健康有关。具有负面影响的人患 CUD 的风险增加。目前，检查该疾病的数据有限。尽管最近有几项研究表明，感知歧视与大麻使用结果之间存在关系表明感知的压力和歧视可能是大麻使用轨迹的重要决定因素。然而，这些研究因依赖于感知暴露的回顾性报告而受到限制。我们建议补充我们的母项目和最先进的生态瞬时。评估 (EMA) 协议，其中包含多种感知歧视措施，以 1) 评估是否遭受长期歧视与 a) 报告的大麻相关问题 b) 随意吸食大麻有关使用量（以克为单位）和 b) 在四个星期的干预期内大麻减少的幅度，以及 2) 使用量生态瞬时评估（EMA）技术，用于衡量感知之间的日常关联我们对拟议补充的中心假设是，经历。歧视和日常感知的不公平待遇将与大麻使用结果有关。这项研究的基本原理是它将提供第一个也是唯一一个关于这一重要的实时数据，但是因此，我们的研究结果将直接影响我们对过去影响的理解。以及大麻使用和滥用方面持续存在的种族歧视。