Training future leaders at the chemistry-biology interface

在化学-生物学界面培训未来的领导者

• 批准号: 10418785
• 负责人: JEREMY BASKIN
• 金额: $ 41.63万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10418785
• 关键词: Biology; Chemistry; Future; Training

Abstract This proposal describes plans to continue a rigorous chemistry-biology interface (CBI) predoctoral training program that is student-centered and designed to provide trainees with core and cross training in chemistry and biological sciences, various abilities to push the frontier of biomedical research at the chemistry-biology interface, and the skills and awareness for diverse career paths. The program, which has been continuously funded by the NIH since 1996, also promotes interdisciplinary collaborative research across the Cornell campus. We request funds to support 10 predoctoral trainees. Each trainee will carry out his or her doctoral thesis research with one or more of 30 faculty mentors affiliated with seven participating units: Chemistry and Chemical Biology, Biological and Biomedical Sciences, Chemical and Biomolecular Engineering, Microbiology and Immunology, Biochemistry and Molecular Cell Biology, Plant Biology, and Nutritional Sciences. Participating faculty have well-funded research programs in chemistry with strong connections to biology or vice versa. Students undergo training in areas that are broadly distributed over chemistry (synthetic organic, bioorganic, bioinorganic, biophysical, natural products, X-ray crystallography, metabolomics, and proteomics) and biology (protein structure and function, enzymology, immunology, signal transduction, chemotaxis, cell biology, host/pathogen interactions, and genomics). The CBI program continues to successfully merge the cultures of chemistry and biology with effective didactic and programmatic initiatives, including the adaptation of evidence-based training strategies and mentor training. CBI trainees take a core set of rigorous courses in both chemistry and biology and undergo responsible conduct of research training as well as rigor and reproducibility training. Trainees attend seminars in their core disciplines, participate together with faculty in a CBI seminar program, and organize an annual CBI symposium that features speakers from diverse career sectors. In addition to research training, our CBI training program puts career awareness and transferable skills training front and center. We design our career awareness and transferable skills workshops to address gaps between career skills needed and skills developed in PhD training that are reported in the literature and obtained through large-scale surveys. We require a sabbatical internship (or employer site visits in special cases) to allow trainees to explore different career options first-hand. These career training activities are designed based on the eight principles of experiential learning. The CBI training activities are accessible to students who are not financially supported by the CBI program and thus have a larger impact on Cornell campus. The program continues to produce a high-caliber cohort of trainees, who are increasingly more diverse due to our continued recruitment efforts, with strong publication records and career outcomes without increasing the time to degree.

抽象的 该建议描述了继续进行严格的化学生物学接口（CBI）培训前培训的计划 以学生为中心的计划，旨在为受训者提供化学和交叉培训 生物科学，在化学生物学界面上推动生物医学研究前沿的各种能力， 以及各种职业道路的技能和意识。该计划一直由 自1996年以来，NIH还促进了整个康奈尔大学校园的跨学科合作研究。我们要求 资金支持10位占主导地位的学员。每个实习生将与一个人一起进行博士学位论文研究 或30位教师指导者中有七个参与单元：化学和化学生物学，生物学 以及生物医学科学，化学和生物分子工程，微生物学和免疫学，生物化学 以及分子细胞生物学，植物生物学和营养科学。参与的教师资金充足 化学研究计划与生物学有密切的联系，反之亦然。学生接受培训 广泛分布在化学上的区域（合成有机，生物有机，生物有机，生物物理，天然 产品，X射线晶体学，代谢组学和蛋白质组学）和生物学（蛋白质结构和功能， 酶学，免疫学，信号转导，趋化性，细胞生物学，宿主/病原体相互作用和 基因组学）。 CBI计划继续成功地将化学和生物学培养物与有效合并 教学和程序化计划，包括适应循证培训策略和导师 训练。 CBI学员参加了化学和生物学的一系列严格课程，并接受了负责任的核心课程 进行研究培训以及严格和可重复性培训。学员参加了他们的核心研讨会 学科，与教师一起参加CBI研讨会计划，并组织年度CBI研讨会 这是来自不同职业领域的演讲者。除了研究培训外，我们的CBI培训计划 将职业意识和可转移技能培训的前提和中心提升。我们设计了职业意识和 可转移技能讲习班，以解决所需的职业技能与博士培训中开发的技能之间的差距 在文献中报告的，并通过大规模调查获得。我们需要休假实习 （或在特殊情况下雇主网站访问），以允许学员亲身探索不同的职业选择。这些 职业培训活动是根据体验式学习的八个原则设计的。 CBI培训 没有CBI计划在财务上支持的学生可以访问活动，因此有更大的活动 对康奈尔校园的影响。该计划继续产生高素质的学员 由于我们继续招聘工作，越来越多样化，并具有强大的出版记录和职业 结果没有增加时间。