Administrative core

行政核心

• 批准号: 10415105
• 负责人: Johann Eli Gudjonsson
• 金额: $ 21.87万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-06-01 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10415105
• 关键词: Address; Advisory Committees; Animal Model; Area; Award; Big Data; Biology; Cell Culture Techniques; Clinic; Collaborations; Communication; Communities; Cutaneous; Dermatology; Development; Disease; Effectiveness; Electronic Mail; Ensure; Environment; Evaluation; Fostering; Funding; Genetically Engineered Mouse; Goals; Grant; Health; Individual; Inflammatory; Infrastructure; Institution; Knowledge; Lead; Leadership; Mentors; Michigan; Mission; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Newsletter; Pathogenesis; Patients; Personnel Management; Recording of previous events; Research; Research Activity; Research Infrastructure; Research Personnel; Resources; Schools; Science; Series; Services; Skin; Surveys; System; Training; Translating; Travel; Universities; Visit; Work; base; improved; innovation; interest; member; model design; operation; programs; skin disorder; success; symposium; tool; web site; Address; Advisory Committees; Animal Model; Area; Award; Big Data; Biology; Cell Culture Techniques; Clinic; Collaborations; Communication; Communities; Cutaneous; Dermatology; Development; Disease; Effectiveness; Electronic Mail; Ensure; Environment; Evaluation; Fostering; Funding; Genetically Engineered Mouse; Goals; Grant; Health; Individual; Inflammatory; Infrastructure; Institution; Knowledge; Lead; Leadership; Mentors; Michigan; Mission; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Newsletter; Pathogenesis; Patients; Personnel Management; Recording of previous events; Research; Research Activity; Research Infrastructure; Research Personnel; Resources; Schools; Science; Series; Services; Skin; Surveys; System; Training; Translating; Travel; Universities; Visit; Work; base; improved; innovation; interest; member; model design; operation; programs; skin disorder; success; symposium; tool; web site

The University of Michigan Department of Dermatology has a long history of productive research in areas highly relevant to the NIAMS mission but there are untapped opportunities for engagement with multiple investigators outside of the department whose interests are also highly relevant to skin biology and disease. Cross-cutting collaborations are particularly important in this era of team science, when groups with deep knowledge in defined areas can work together to collectively address fundamental questions in basic biology and disease that would be difficult, if not impossible, to tackle in individual labs. The proposed University of Michigan Skin Biology and Diseases Resource-based Center (UM-SBDRC) will provide investigators at Michigan, and several other institutions, access to outstanding Resource Cores and Center activities. The ultimate goals of the Center include facilitating independently-funded research into skin biology and disease, with an emphasis on inflammatory skin disorders; fostering the development of team-science, combining big- data approaches with functional studies in cell culture and genetically-engineered mouse models; and attracting additional investigators into cutaneous research relevant to the NIAMS mission. The UM-SBDRC Administrative Core will coordinate Center activities and oversee management of the Resource Cores. It will achieve this by 1) establishing a strong leadership and support team, 2) building an effective set of committees to assist with Center and Resource Core administration, 3) fostering effective interactions with Resource Cores, 4) optimizing financial administration throughout the Center, and 5) developing survey tools and metrics to assess Center and Resource Core effectiveness. The Administrative Core will also build an effective communications platform, which will include a dedicated, interactive UM-SBDRC website, a biannual newsletter, and program and informational emails. In addition, to enhance the research environment and provide greater opportunities for member interaction and collaboration, the Administrative Core will build a robust Enrichment Program. This will include 1) a Pilot & Feasibility Program, 2) Mentoring Program, 3) Travel Award Program, 4) quarterly Visiting Speaker Series, and 5) Annual Symposium. As a result of these Center activities and the outstanding training and services provided by the Resource Cores, the UM-SBDRC will have a powerful and sustained impact on cutaneous biology research at the University of Michigan and elsewhere. The Center will facilitate skin-related research activities by its 50 members, help bring new investigators into the field, enhance research infrastructure for improved communication and scientific interactions, significantly increase the visibility of the cutaneous research community at the University of Michigan, and lead to major new research initiatives and external support for team-science projects relevant to the NIAMS mission. Ultimately, the research infrastructure and programs provided through the UM-SBDRC will help translate basic discoveries from the lab to the clinic, improving the health of patients with a variety of skin disorders.

密歇根大学皮肤科系在领域有悠久的生产研究历史 与NIAMS的任务高度相关，但有未开发的机会与多个 该部门以外的调查人员的兴趣也与皮肤生物学和疾病高度相关。 在这个团队科学时代，当具有深度的小组 定义领域的知识可以共同解决基本生物学的基本问题 以及在个别实验室中解决的疾病，即使不是不可能的疾病。拟议的大学 密歇根州皮肤生物学和疾病基于资源的中心（UM-SBDRC）将为调查人员提供 密歇根州和其他几个机构，可以访问出色的资源核心和中心活动。这 该中心的最终目标包括促进对皮肤生物学和疾病的独立研究， 重点是炎症性皮肤疾病；促进团队科学的发展，结合大型 数据方法与细胞培养和遗传工程小鼠模型的功能研究相关；和 吸引其他研究人员参与与NIAMS任务相关的皮肤研究。 UM-SBDRC 行政核心将协调中心活动并监督资源核心的管理。会 通过1）建立强大的领导和支持团队，2）建立有效的委员会 为了协助中心和资源核心管理，3）促进与资源的有效互动 核心，4）优化整个中心的金融管理，5）开发调查工具和指标 评估中心和资源核心有效性。行政核心还将建立有效的 通信平台将包括一个专用的交互式UM-SBDRC网站，每年一次 新闻通讯以及计划和信息电子邮件。此外，以增强研究环境和 为会员互动与协作提供更多机会，行政核心将建立一个 强大的丰富计划。这将包括1）飞行员和可行性计划，2）指导计划，3）旅行 奖励计划，4）季度访问者系列和5）年度研讨会。由于这些中心 资源核心提供的活动以及杰出的培训和服务，UM-SBDRC将拥有 密歇根大学和其他地方对皮肤生物学研究的强大而持续的影响。 该中心将促进其50名成员与皮肤相关的研究活动，帮助将新的调查人员带入 该领域，增强了改善沟通和科学互动的研究基础设施 提高密歇根大学皮肤研究界的知名度，并导致主要 与NIAMS任务相关的团队科学项目的新研究计划和外部支持。 最终，通过UM-SBDRC提供的研究基础架构和计划将有助于翻译基本 从实验室到诊所的发现，改善了各种皮肤疾病的患者的健康状况。