Cancer Imaging

癌症影像

• 批准号: 10411094
• 负责人: Jason Thanh Lee
• 金额: $ 9.19万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-04 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10411094
• 关键词: Accounting; Animal Disease Models; Biological Process; Bioluminescence; Budgets; Cancer Biology; Cancer Center Support Grant; Consult; Cyclotrons; Data Analyses; Detection; Diagnostic; Discipline of Nuclear Medicine; Disease Progression; Doctor of Philosophy; Educational workshop; Ensure; Faculty; Fluorescence; Fostering; Funding; Goals; Hematologic Neoplasms; Image; Imaging Device; Imaging technology; Immunology; Individual; Institutes; Knowledge; Laboratories; Magnetic Resonance Imaging; Magnetism; Malignant Neoplasms; Medical; Medical Imaging; Molecular Biology; Monitor; Oncology; Physics; Play; Positron-Emission Tomography; Publications; Radiobiology; Radiochemistry; Research; Research Personnel; Resource Sharing; Role; Scientist; Screening for cancer; Services; Site; Technology; Therapeutic; Time; Tracer; Training; Translational Research; Work; Workplace; X-Ray Computed Tomography; animal facility; animal imaging; anticancer research; assay development; cancer imaging; cancer immunotherapy; cancer stem cell; design; drug development; experience; experimental study; imaging modality; imaging scientist; improved; in vivo; in vivo imaging; instrument; member; molecular imaging; novel diagnostics; novel therapeutic intervention; optical imaging; particle; pre-clinical research; preclinical imaging; programs; theranostics; ultrasound

PROJECT SUMMARY The Cancer Imaging Shared Resource (CI-SR) provides advanced preclinical imaging technologies and services for studying cancer biology, early cancer detection, monitoring disease progression, and developing novel diagnostic and theranostic agents. All major small animal imaging modalities are available, including positron emission tomography (PET), magnetic resonance imaging (MRI), x-ray computed tomography (CT), ultrasound and photoacoustics, magnetic particle imaging (MPI), and optical imaging (e.g., bioluminescence, fluorescence, Cerenkov). Since the last review, the CI-SR has acquired new and upgraded imaging instruments, including the first-of-its-kind MPI scanner. In 2020, 54% of users were SCI investigators accounting for approximately 55% of total usage. Members of the Cancer Imaging, Cancer Biology and Cancer Stem Cells, Cancer Therapeutics, Radiation Biology, Cancer Immunotherapy, and Hematologic Malignancies programs regularly use the CI-SR, with the heaviest use coming from the Cancer Imaging, Cancer Biology and Cancer Stem Cells, and Cancer Therapeutics programs. The CI-SR contributed to over 55 cancer-focused publications (15 high-impact). The annual budget of the CI-SR is $1,021,174, yet the CCSG request is $106,372. Accordingly, the CI-SR leverages extensive institutional support and seeks 10% from CCSG funds. The CI-SR is focused on two major scientific aims: (1) to provide access to state-of-the-art and first-of-its-kind in vivo imaging technologies and services pertinent to cancer research and (2) to educate, train, and consult with SCI members in basic and advanced imaging methods and data analysis through training courses, seminars, and workshops.

项目摘要 癌症成像共享资源（CI-SR）提供高级临床前成像技术和服务 用于研究癌症生物学，早期癌症检测，监测疾病进展和发展新颖 诊断和治疗剂。所有主要的小动物成像方式都可以使用，包括正电子 排放断层扫描（PET），磁共振成像（MRI），X射线计算机断层扫描（CT），超声 和光声，磁性粒子成像（MPI）和光学成像（例如，生物发光，荧光， Cerenkov）。自上次评论以来，CI-SR已购买了新的和升级的成像仪器，包括 首先使用的MPI扫描仪。在2020年，有54％的用户是SCI调查人员，约占55％ 总用途。癌症成像，癌症生物学和癌症干细胞的成员，癌症治疗剂， 放射生物学，癌症免疫疗法和血液学恶性肿瘤计划定期使用CI-SR， 癌症成像，癌症生物学和癌症细胞以及癌症最重的用途 治疗计划。 CI-SR贡献了55多个以癌症为中心的出版物（15个高影响力）。这 CI-SR的年度预算为1,021,174美元，但CCSG请求为106,372美元。因此，CI-SR的利用 广泛的机构支持，并从CCSG基金中寻求10％。 CI-SR专注于两个主要科学 目的：（1）为体内成像技术和服务提供访问最先进的和首先的访问权限 与癌症研究以及（2）有关基础和先进的SCI成员的教育，培训和咨询 成像方法和数据分析通过培训课程，研讨会和研讨会。