Chemistry-Biology Interface T32

化学-生物接口 T32

• 批准号: 10409763
• 负责人: Jennifer J Kohler
• 金额: $ 16.12万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10409763
• 关键词: Biology; Chemistry

UT Southwestern Medical Center (UTSW) has a long institutional history of valuing and promoting collaborative science, and provides a unique environment for chemistry and biochemistry graduate students to participate in interdisciplinary education and research. This proposal embodies the culture of UTSW and outlines a new predoctoral training program dedicated to providing interdisciplinary training at the Chemistry- Biology Interface (CBI). Organized with a Drug Discovery mindset, our training program equips young scientists with the fundamental knowledge and interdisciplinary skills that are needed to tackle challenging diverse problems in biomedical research and to identify new areas of opportunity. As a guiding principle, we believe that building a strong and diverse biomedical workforce requires developing excellence in individual disciplines while fostering collaborative efforts among experts in disparate fields. Students complete rigorous graduate training in either chemistry or biology, while also developing broad knowledge of the most important principles and problems in both fields. The CBI at UTSW program is designed to meet three objectives: First, students will become experts in their individual fields of chemistry or biology. Second, students will be knowledgeable about the most important principles and problems in both fields. Finally, students will be skilled in communicating scientific challenges and discoveries to a wide range of individuals, from experts to laypeople. The CBI program will directly support two students each during years 2 and 3 of their predoctoral training and will also train McKnight fellows who are supported by UTSW through private funds; all trainees will continue to benefit from CBI resources until graduation. The program will capitalize on its setting within a leading medical center to offer training activities that focus on preclinical Drug Discovery. The training faculty members for the CBI program are part of a rich network of collaborations that scaffold the training program, but also extend throughout the University and into the larger scientific community. Together, these training aspects are designed to provide students with the scientific knowledge and collaborative prowess to work together in an interdisciplinary team to address the most compelling and intractable scientific questions, with the goal of developing the next generation of biomedical researchers. “Value-added” features of the UTSW CBI training program include: (a) an advanced course in Drug Discovery taught by experts in academia and industry; (b) an improved Enzymes and Disease course that facilities interdisciplinary and collaborative science through peer-led team learning; (c) personalized instruction in scientific writing, specifically aimed at funding opportunities; (d) training in scientific communication through coached production of ScienceSketch YouTube videos; (e) trainee-designed participation in mini-sabbaticals to enhance cross-disciplinary and non-academic training; (f) monthly meetings between CBI trainees and faculty advisory committee that offer collegial support and career enrichment opportunities; and (g) support for teaching and outreach activities.

UT西南医学中心（UTSW）具有悠久的估值和促进的机构历史 协作科学，为化学和生物化学研究生提供了独特的环境 参加跨学科的教育和研究。该建议体现了UTSW和 概述了一项新的专业培训计划，该计划致力于在化学中提供跨学科培训 - 生物学接口（CBI）。我们的培训计划以药物发现心态组织，使年轻 具有基本知识和跨学科技能来应对挑战所需的基本知识和跨学科技能的科学家 潜水员在生物医学研究中的问题并确定新的机会领域。作为指导原则，我们 相信建立强大而多样化的生物医学劳动力需要个人发展 学科在培养不同领域专家之间的合作努力的同时。学生完全严格 化学或生物学的研究生培训，同时也发展了最重要的广泛知识 这两个领域的原理和问题。 UTSW计划的CBI旨在满足三个目标：首先 学生将成为其化学或生物学各个领域的专家。第二，学生将是 知识渊博，这两个领域最重要的原则和问题。最后，学生将 从专家到 外行。 CBI计划将直接在其前2年和第3年直接支持两个学生 培训，还将培训麦克奈特（McKnight）的研究员，他们得到了utsw通过私人资金支持的；所有培训 将继续从CBI资源中受益，直到毕业。该计划将利用其设置 领先的医疗中心提供着专注于临床前药物发现的培训活动。培训教师 CBI计划的成员是丰富的合作网络的一部分 但也扩展到整个大学，并进入更大的科学界。在一起，这些训练 各个方面旨在为学生提供科学知识和协作能力来工作 一起在一个跨学科团队中一起解决最引人注目，最棘手的科学问题， 发展下一代生物医学研究人员的目标。 UTSW CBI的“增值”功能 培训计划包括：（a）由学术界专家和 行业; （b）设施跨学科和协作科学的改进的酶和疾病课程 通过同伴领导的团队学习； （c）科学写作的个性化教学，专门针对资金 机会； （d）通过辅导的Sciencesketch YouTube培训科学交流的培训 视频； （e）受训者设计的小型游览以增强跨学科和非学术的参与 训练; （f）CBI培训和教师咨询委员会之间的每月会议，这些委员会提供大学支持 和职业充实机会； （g）支持教学和外展活动。