Testing the impact of smartphone-based messaging to support young adult smoking cessation

测试基于智能手机的消息传递对支持年轻人戒烟的影响

• 批准号: 10404675
• 负责人: Johannes Thrul
• 金额: $ 37.46万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10404675
• 关键词: Abstinence; Address; Adolescent; Affect; Age; Alcohols; Area; Biochemical; Cannabis; Cellular Phone; Cigarette; Clinical Practice Guideline; Cognitive Therapy; Control Groups; Coping Skills; Data; Devices; Dose; Ecological momentary assessment; Electronic cigarette; Evidence based intervention; Exposure to; Facebook; Future; Goals; Home; Individual; Intervention; Life; Light; Location; Morbidity - disease rate; Outcome; Participant; Patients; Persons; Phase; Population; Premature Mortality; Prevalence; Probability; Protocols documentation; Randomized; Randomized Clinical Trials; Research; Services; Smoker; Smoking; Smoking Behavior; Smoking Cessation Intervention; Stress; Surveys; Target Populations; Testing; Therapeutic Intervention; Time; Tobacco; Tobacco smoking behavior; Tobacco use; United States; Work; age group; alcohol and other drug; base; cognitive testing; design; efficacy evaluation; efficacy testing; evidence base; experience; flexibility; follow-up; group intervention; handheld mobile device; high risk; interest; intervention effect; mindfulness; mortality; novel strategies; primary outcome; psychologic; randomized trial; response; secondary analysis; secondary outcome; smartphone Application; smoking cessation; smoking relapse; tailored messaging; virtual; young adult

PROJECT SUMMARY Tobacco use remains the most important cause of morbidity and premature mortality in the United States. Young adults have high smoking rates and low use of evidence-based smoking cessation services. Smartphones are widely used among young adults and offer a promising strategy to deliver smoking cessation treatment to a large, diverse audience of young adult smokers. Available smoking cessation apps for smartphones are rarely evidence-based and able to deliver intervention content that is tailored to the specific needs of the individual smoker. Little is known how smartphone-based interventions need to be designed and what kind of tailored intervention content they should deliver. While there is evidence for the efficacy of both Cognitive Behavioral Therapy (CBT) and Mindfulness/ Acceptance and Commitment Therapy (ACT) smoking cessation interventions, it is unclear if these approaches are efficacious when implemented in real-time and with young adults. The overall goal of this proposal is to evaluate the efficacy of CBT and ACT-based messages for young adults targeted at specific high-risk situations for smoking. Our team has experience in using smartphones and Ecological Momentary Assessment (EMA) to understand situational predictors of smoking in everyday life, and smoking cessation trials with young adults using Facebook. We have demonstrated feasibility of determining high-risk situations for smoking and delivering tailored messages based on geofence triggers. The specific aims are to: 1) To test CBT and Mindfulness/ACT intervention message efficacy for reducing momentary smoking urges. We will conduct a micro-randomized trial (within-subject randomization) to test the efficacy of CBT and Mindfulness/ACT compared to control messages for reducing smoking urge 15 minutes after message delivery. 2) To test if exposure to urge reduction messages results in changes in smoking behavior over time compared to an EMA only control group. A control group of participants that will complete EMA only without intervention messages will allow us to test, if messages reduce cigarettes per day at end of treatment, 3-, and 6-months follow-up. 3) Explore moderation effects of substance co-use (cannabis, alcohol, other drugs) and exposure to specific location (home, work, bars) on urge reduction message efficacy. Among intervention group participants, we will explore how message efficacy may be moderated by substance co-use and exposure to specific settings. Smoking onset is now more common among young adults than adolescents and early cessation substantially reduces morbidity and mortality from smoking, making age-appropriate, tailored, and scalable interventions for this high priority population ever more important.

项目摘要 烟草的使用仍然是美国发病率和过早死亡率的最重要原因 国家。年轻人的吸烟率很高，低使用循证戒烟服务。 智能手机被广泛用于年轻人，并提供了一种有前途的策略来戒烟 对年轻吸烟者的大量，多样化的受众进行治疗。可用的戒烟应用 智能手机很少以证据为基础，并且能够提供针对特定的特定的干预内容 个体吸烟者的需求。鲜为人知的是如何设计基于智能手机的干预措施和 他们应该提供什么样的量身定制干预内容。 虽然有证据表明认知行为疗法（CBT）和正念/ 接受和承诺疗法（ACT）戒烟干预措施尚不清楚这些方法是否采用 实时和与年轻人实施时，有效。该提议的总体目标是 评估针对特定高风险的年轻人的CBT和基于ACT的信息的功效 吸烟的情况。 我们的团队有使用智能手机和生态瞬时评估（EMA）的经验 了解日常生活中吸烟的情境预测因素，并与年轻人进行戒烟试验 使用Facebook。我们已经证明了确定吸烟高风险情况的可行性 根据Geofence触发器传递量身定制的消息。 具体目的是：1）测试CBT和正念/ACT干预信息的信息功效 减少瞬间吸烟。我们将进行微随机试验（受试者内随机化）至 与减少吸烟冲动的控制消息相比，测试CBT和正念/ACT的功效15 消息传递后几分钟。 2）测试暴露于敦促减少消息是否会导致变化 与仅EMA对照组相比，吸烟行为随着时间的流逝。一个对照组的参与者将 如果消息每天减少香烟，则仅在没有干预消息的情况下完成EMA才能测试 在治疗结束时，3个月和6个月的随访。 3）探索物质共同利用的节制作用（大麻，， 酒精，其他药物）和暴露于敦促减少信息功效的特定位置（家庭，工作，酒吧）。 在干预小组参与者中，我们将探讨如何通过物质调节信息效能 共同使用和暴露于特定设置。 现在，吸烟开始在年轻人中比青少年和早期停止更为普遍 大大降低了吸烟的发病率和死亡率，使年龄适合，量身定制和可扩展 对这种高优先级人群的干预越来越重要。