Ga. Dept. of Agriculture - NARMS

佐治亚州农业部 - NARMS

• 批准号: 10401204
• 负责人: Carrie Crabtree
• 金额: $ 18.2万
• 依托单位: GEORGIA STATE DEPARTMENT OF AGRICULTURE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10401204
• 关键词: Ga.; Dept.; Agriculture; NARMS

NARMS - Project Summary/Abstract The Georgia Department of Agriculture (GDA) is the state agency responsible for regulation of food manufactured facilities and retail establishments. GDA Laboratories (Lab) are the primary servicing laboratories for the regulatory programs and are focused on food analysis for chemical and microbiological contaminants. Since 2011, GDA has pursued FDA grants and cooperative agreements to improve and harmonize our state regulatory and testing capability. Through these grants the Lab achieved accreditation to ISO 17025 international standards which allows our regulatory agencies to perform contractual work on behalf of FDA. Since GDA is Georgia’s regulatory authority over food retail establishments, the agency has inspectors positioned all throughout The State of Georgia. These inspectors are trained to collect samples and return them to our lab for testing that can support regulatory enforcement. Since GDA already has infrastructure designated for sample collection at retail establishments and the analysis of microorganisms by the Lab, this award opportunity NARMS (National Antimicrobial Resistance Monitory System) should make a good fit to be implemented by GDA. The Georgia Department of Public Health (GDPH) Laboratory is currently awarded this grant but has contacted GDA to request assistance or taking it over since the COVID 19 pandemic has become their top priority. In summary, GDA inspectors will collect the samples and send them to the Lab per routine protocols. The Lab will screen the samples for the target organisms suggested in the Funding Opportunity Award (FOA). The Lab will utilize methods described in the project protocol in addition to screening by approved and validated ELISA or PCR platforms. Isolates showing typical characteristics will be further examined and confirmed or sent to FDA for further evaluation. As needed, GDPH has agreed to also assist in in Whole Genome Sequencing of the isolates, since GDA does not currently have that ability, in addition to mentoring of the methods and program until fully established. The Lab has developed and demonstrated successful relationships with their regulatory partners and the GDPH Lab, which should indicate its ability to fulfill this objective. The Lab also routinely performs thousands of microbiological analyses on retail food samples annually. If awarded, GDA will be capable of enhancing and strengthening antimicrobial resistance surveillance data. This in turn can be used to inform public health stakeholders about populations of resistant strains and if current policy and practices are adequate for overall safety of consumers.

NARMS - 项目摘要/摘要 佐治亚州农业部 (GDA) 是负责监管农业的国家机构 GDA 实验室（实验室）是主要服务机构。 监管计划实验室，专注于化学和食品分析 自 2011 年以来，GDA 一直在寻求 FDA 的资助和合作协议，以解决微生物污染物问题。 通过这些拨款，实验室可以改善和协调我们的州监管和测试能力。 获得 ISO 17025 国际标准认证，使我们的监管机构能够 由于 GDA 是佐治亚州食品零售的监管机构，因此代表 FDA 执行合同工作。 该机构在佐治亚州各地都设有检查员。 检查员接受过收集样本并将其返回我们实验室进行测试的培训，以支持 监管执法。 由于 GDA 已经拥有指定用于零售机构样本采集的基础设施 以及实验室对微生物的分析，本次获奖机会 NARMS（国家抗菌药物 阻力监测系统）应该非常适合由 GDA 实施。 公共卫生部 (GDPH) 实验室目前获得了这笔资助，但已联系 GDA 由于 COVID 19 大流行已成为他们的首要任务，因此请求援助或接管它。 总之，GDA 检查员将按照例行程序收集样品并将其发送至实验室 实验室将筛选资助中建议的目标生物样本。 机会奖 (FOA) 除了使用项目协议中描述的方法外，实验室还将利用项目协议中描述的方法。 通过经批准和验证的 ELISA 或 PCR 平台进行筛选，显示典型特征。 需要进一步检查和确认或发送给 FDA 进行进一步评估，GDPH 已同意。 还可以协助分离株的全基因组测序，因为 GDA 目前不具备这种能力 能力，以及对方法和计划的指导，直到完全建立。 该实验室已与监管合作伙伴建立并展示了成功的关系 GDPH 实验室，应表明其实现这一目标的能力。 每年对零售食品样品进行数千次微生物分析，如果获奖，GDA 将获得殊荣。 能够增强和加强抗菌药物耐药性监测数据。 用于向公共卫生利益相关者通报耐药菌株的种群情况，以及当前的政策和措施是否有效 实践足以保障消费者的整体安全。