Multidisciplinary Schizophrenia Research Training

多学科精神分裂症研究培训

• 批准号: 10400081
• 负责人: William T. Carpenter
• 金额: $ 4.02万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10400081
• 关键词: Research Training; Schizophrenia; multidisciplinary

Project Summary This is the third competitive renewal of a T32 training grant at the Maryland Psychiatric Research Center (MPRC), originally funded in 2003 (MH067533). The goal of the proposed program is to prepare MDs, PhDs and PharmDs interested in basic or clinical research for a career in translational research in mental health with a focus on schizophrenia and psychosis-related disorders. The MPRC, an Organized Research Center of the University of Maryland School of Medicine and division of the Department of Psychiatry, is a state-of-the-art center for research on schizophrenia and related disorders, located on the grounds of the Spring Grove Hospital Center, a State of Maryland inpatient mental health facility located just outside Baltimore. MPRC research engages a broad range of integrated and translational science to investigate specific pathologies associated with schizophrenia and related disorders including; neurophysiology, neuroimaging, basic neurochemistry, circuitry modeling in rodents and miniature pigs, disease etiology, domains of psychopathology and endophenotypes, neurocognition, experimental therapeutics and clinical trials. The MPRC’s collaborative framework has supported NIMH P50 awards for over 30 years, most recently a CIDAR and presently in year 6 of a Silvio O. Conte Centerr (Fall 2019). The MPRC is characterized by continuous interaction and collaboration among preclinical and clinical investigators- we share the same space, seminar schedules, faculty meetings and general research interests. This integrated experience prepared several faculty at MPRC to take an active role in supporting NIMH workshops developing behavioral constructs for the RDoC initiative and one PI on this application is a senior advisor to NIMH assigned to the RDoC Unit. Scientific opportunities and collaborations are enriched with extensive involvement with other components of the University of Maryland School of Medicine and School of Pharmacy and the nearby University of Maryland Baltimore County (UMBC). Postdoctoral training offered under this T32 fellowship has a primary focus on both basic neuroscience and clinical investigations of schizophrenia and related disorders. All trainees are educated on the translational perspective of the MPRC and provided mentors and didactic training in both clinical psychopathology and basic neuroscience as well as structured career planning. We are unique in that we have a broad array of opportunities for multidisciplinary training (we uniquely accept PharmDs) as well as having nonresearch focused clinical personnel integrated in the curriculum to training scientists in pragmatic, real world needs of the field. The culture at the MPRC provides the foundation for our success in recruiting and training post-doctoral fellows for a scientific career, including clinician scientists. Graduates of the program lead productive, successful research-intensive careers. This competitive five-year renewal application proposes to leverage our previous success and continue to improve our training approach (including mentor training) to produce productive, well-rounded translationally-focused scientists.

项目概要 这是马里兰精神病学研究中心 T32 培训补助金的第三次竞争性更新 (MPRC)，最初于 2003 年资助 (MH067533) 拟议计划的目标是培养医学博士、博士。 对基础或临床研究感兴趣的药学博士，从事心理健康转化研究的职业 MPRC 是一个有组织的研究中心，重点关注精神分裂症和精神病相关疾病。 马里兰大学医学院和精神病学系是最先进的 精神分裂症及相关疾病研究中心，位于斯普林格罗夫 (Spring Grove) 医院中心 (Hospital Center) 是马里兰州住院精神卫生机构，位于巴尔的摩市郊。 研究涉及广泛的综合和转化科学来调查特定的病理学 与精神分裂症和相关疾病相关，包括神经生理学、神经影像学、基础疾病 神经化学、啮齿动物和小型猪的电路建模、疾病病因学、领域 精神病理学和内表型、神经认知、实验治疗和临床试验。 MPRC 的协作框架已支持 NIMH P50 奖项 30 多年，最近的一个是 CIDAR 目前正处于 Silvio O. Conte Centerr 的第 6 年（2019 年秋季），MPRC 的特点是持续。 临床前和临床研究人员之间的互动和协作 - 我们共享相同的空间、研讨会 日程安排、教师会议和一般研究兴趣这些综合经验准备了一些。 MPRC 的教师将在支持 NIMH 研讨会上发挥积极作用，为开发行为结构 RDoC 倡议和该应用程序的一名 PI 是 NIMH 分配给 RDoC 科学部门的高级顾问。 通过与其他部门的广泛参与，机会和合作变得更加丰富 马里兰大学医学院和药学院以及附近的马里兰大学 巴尔的摩县 (UMBC) 的 T32 奖学金提供的博士后培训主要侧重于这两方面。 所有学员都接受了精神分裂症和相关疾病的基础神经科学和临床研究的教育。 从 MPRC 的转化角度出发，并在临床和临床两方面提供导师和教学培训 我们的独特之处在于我们拥有精神病理学和基础神经科学以及结构化职业规划。 广泛的多学科培训机会（我们唯一接受药学博士）以及 将非研究重点的临床人员纳入课程中，以务实、真实的方式培训科学家 MPRC 的文化为我们在招聘和培训方面取得成功奠定了基础。 为科学职业培训博士后研究员，包括该项目负责人的毕业生。 这项具有竞争力的五年续签申请旨在实现富有成效、成功的研究密集型职业。 利用我们之前的成功并继续改进我们的培训方法（包括导师培训） 培养富有成效、全面发展、专注于转化的科学家。