Cancer Control and Survivorship
癌症控制和生存
基本信息
- 批准号:10394828
- 负责人:
- 金额:$ 15.53万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1996
- 资助国家:美国
- 起止时间:1996-12-01 至 2025-03-31
- 项目状态:未结题
- 来源:
- 关键词:AddressAreaBehavioralBehavioral GeneticsBiologicalBreast Cancer survivorCancer BurdenCancer Center Support GrantCancer ControlCancer Control ResearchCancer PatientCancer SurvivorCancer SurvivorshipCatchment AreaChildClinicalCognitive TherapyCollaborationsComplexComprehensive Cancer CenterCountyDiagnosisDirect CostsDiseaseDoctor of PhilosophyDoseEnvironmentEpidemiologic MethodsEpidemiologyEpigenetic ProcessEthnic OriginFacultyFundingGenderGenomic approachGenomicsHealthHealth PolicyHuman Papilloma Virus VaccinationImmigrantIncidenceInterdisciplinary StudyInterventionIntervention StudiesIntervention TrialJournalsLatina PopulationLettersLife StyleLong-Term SurvivorsLos AngelesLow incomeMachine LearningMalignant Childhood NeoplasmMalignant NeoplasmsMalignant neoplasm of lungMedical OncologistMethodologyMethodsMolecularMorbidity - disease rateObservational StudyOutcomeOutcomes ResearchPatientsPeer ReviewPopulationPopulations at RiskPregnancyPrimary PreventionPsychologistPublic Health SchoolsPublicationsQuality of CareReproducibilityResearchResearch PersonnelResource SharingRiskRisk FactorsScienceScreening for cancerSleeplessnessSurvivorsSymptomsTai JiTarget PopulationsTestingVulnerable PopulationsWorkadverse outcomebasecancer carecancer diagnosiscancer health disparitycancer preventioncancer riskcare deliverycollegecomputed tomography screeningcost effectivenessdesigndissemination researcheconomic indicatorend of lifeepidemiology studyethnic diversityethnic minoritygenetic risk factorhealth disparityhigh riskimplementation researchimplementation scienceimprovedinnovationinter-institutionallung cancer screeningmedical schoolsmemberminority childrenmortalityprogramsprotective factorspsychologicpsychosocialracial and ethnicracial and ethnic disparitiessafety netscreeningscreening guidelinessocialsocioeconomicsstandard of caresurvivorshipsynergismunderserved communityuptakevaccine acceptance
项目摘要
CANCER CONTROL AND SURVIVORSHIP RESEARCH PROGRAM (CCS)
ABSTRACT
For over 25 years, the UCLA Jonsson Comprehensive Cancer Center (JCCC) has produced impactful research
in cancer prevention and control, spanning the entire cancer control continuum. This work is based in the Cancer
Control and Survivorship (CCS) Program, which has the breadth and depth of faculty expertise to tackle existing
and emerging cancer control problems using approaches from genomics, machine learning, smarter cancer
prevention and screening strategies, health outcomes research, and implementation science which can guide
cancer care delivery from primary prevention through end-of-life settings and can inform health policy.
There are 46 members in the CCS Program representing 16 departments spanning the Fielding School of Public
Health, the David Geffen School of Medicine, and the College of Letters and Sciences. As of March 1, 2019,
Program support was $26,487,925 in direct cost funding, of which $3,850,239 (15%) was from the NCI and
$12,843,034 (48%) was peer-reviewed. Program research resulted in 1,127 publications between 2013-2018, of
which 21% were intra-programmatic and 13% were inter-programmatic collaborations, with extensive use of the
BASE shared resource. Also, 73% of total publications were inter-institutional collaborations, with 34% of the
total in high-impact (IF ≥10, or field leading) journals.
The CCS Program has three specific aims. Aim 1: To identify risk and protective factors for cancer as well as
the most effective strategies for reducing cancer risk in the population. Aim 2: To determine the best
methodologies for cancer screening and diagnosis and to identify the most effective strategies to increase uptake
of cancer screening at the population level. Aim 3: To conduct research with findings that have the potential to
reduce avoidable morbidity and mortality among patients with cancer and long-term survivors of cancer. CCS
research is informed by, and highly responsive to, the cancer burden and needs of the JCCC catchment area,
Los Angeles County (LAC). The county cancer burden is high, with large differences in cancer risk factors and
cancer outcomes by ethnicity, gender, and socio-economic indicators. Thus, cross cutting themes that address
health disparities and improvements in health outcomes permeate the research conducted by CCS investigators.
Examples of impactful program research in the prior project period include: (1) Research showing very low rates
of HPV vaccination for low income, ethnic minority adolescents in safety-net settings, resulting in multiple trials
to improve vaccine uptake. (2) A study demonstrating the cost effectiveness of low-dose lung cancer CT
screening that influenced the national dialog on lung cancer screening guidelines. (3) Findings that incidence
rates for several childhood cancers among children of US born Latinas were higher than for children of immigrant
Latinas, implicating lifestyle and environment during pregnancy. (4) A study in breast cancer survivors with
severe insomnia showing that standard-of-care cognitive behavioral therapy-insomnia (CBT-I) or Tai Chi Chih
(TCC) were both effective, but access to CBT-I therapists is limited, whereas TCC is widely accessible.
癌症控制与生存研究计划(CCS)
抽象的
超过25年,加州大学洛杉矶分校乔森森综合癌症中心(JCCC)进行了有影响力的研究
在癌症预防和控制中,跨越了整个癌症控制连续性。这项工作基于癌症
控制和生存计划(CCS)计划,具有教师专业知识的广度和深度来解决现有
使用基因组学,机器学习,更智能癌症的方法来控制癌症控制问题
预防和筛查策略,健康成果研究和实施科学,可以指导
从初级预防到生命终止环境的癌症护理可以为卫生政策提供信息。
CCS计划中有46个成员,代表16个部门,跨越了公立学校
健康,大卫·格芬医学院和文学和科学学院。截至2019年3月1日,
计划支持为$ 26,487,925的直接成本资金,其中3,850,239美元(15%)来自NCI,并且
$ 12,843,034(48%)进行了同行评审。计划研究导致2013 - 2018年之间有1,127个出版物
21%是截面性的,有13%是程序间合作,广泛使用了
基本共享资源。此外,总出版物中有73%是机构间合作,其中34%
在高影响力(如果≥10或田间引导)期刊中。
CCS计划具有三个具体目标。目标1:确定癌症的风险和保护因素
降低人群癌症风险的最有效策略。目标2:确定最好的
癌症筛查和诊断的方法,并确定增加摄取的最有效策略
在人群水平上进行癌症筛查。目的3:进行研究,发现有可能
降低癌症患者和癌症长期存活的可避免的发病率和死亡率。 CCS
研究是由癌症的癌症和JCCC集水区的需求告知的,并且高度敏感
洛杉矶县(LAC)。伯恩县癌症很高,在癌症危险因素和
种族,性别和社会经济指标的癌症结果。那是解决问题的交叉切割主题
健康分布和健康结果的改善渗透了CCS研究人员进行的研究。
上一项项目期间有影响力的计划研究的示例包括:(1)研究表明利率非常低的研究
HPV疫苗接种的低收入,少数民族青少年在安全网络中的疫苗接种,导致多次试验
改善疫苗的摄取。 (2)一项研究表明低剂量肺癌CT的成本效益
影响肺癌筛查指南的全国对话的筛查。 (3)该事件的发现
我们出生的拉丁裔儿童中几种童年癌的发生率高于移民儿童
拉丁裔,暗示怀孕期间的生活方式和环境。 (4)一项研究乳腺癌生存的研究
严重的失眠表明,护理标准的认知行为疗法 - Insomnia(CBT-I)或Tai Chi Chih
(TCC)都是有效的,但是访问CBT-I治疗师是有限的,而TCC可以广泛使用。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
PATRICIA A. GANZ其他文献
PATRICIA A. GANZ的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('PATRICIA A. GANZ', 18)}}的其他基金
Cognitive Training for Cancer-related Cognitive Impairment: A Multi-Center Randomized Controlled Trial
癌症相关认知障碍的认知训练:多中心随机对照试验
- 批准号:
10562299 - 财政年份:2023
- 资助金额:
$ 15.53万 - 项目类别:
Advancing Analysis and Interpretation of Adverse Events and PROs in Cancer Clinical Trials
推进癌症临床试验中不良事件和 PRO 的分析和解释
- 批准号:
10884827 - 财政年份:2023
- 资助金额:
$ 15.53万 - 项目类别:
Advancing Analysis and Interpretation ofAdverse Events and PROs in Cancer Clinical Trials
推进癌症临床试验中不良事件和 PRO 的分析和解释
- 批准号:
10477392 - 财政年份:2018
- 资助金额:
$ 15.53万 - 项目类别:
Advancing Analysis and Interpretation ofAdverse Events and PROs in Cancer Clinical Trials
推进癌症临床试验中不良事件和 PRO 的分析和解释
- 批准号:
10241463 - 财政年份:2018
- 资助金额:
$ 15.53万 - 项目类别:
Advancing Analysis and Interpretation ofAdverse Events and PROs in Cancer Clinical Trials
推进癌症临床试验中不良事件和 PRO 的分析和解释
- 批准号:
9788322 - 财政年份:2018
- 资助金额:
$ 15.53万 - 项目类别:
ENHANCING OUTCOMES IN YOUNG BREAST CANCER SURVIVORS: A PROGRAM OF THE UCLA-LIVEST
提高年轻乳腺癌幸存者的治疗效果:UCLA-LIVEST 项目
- 批准号:
8332706 - 财政年份:2011
- 资助金额:
$ 15.53万 - 项目类别:
ENHANCING OUTCOMES IN YOUNG BREAST CANCER SURVIVORS: A PROGRAM OF THE UCLA-LIVEST
提高年轻乳腺癌幸存者的治疗效果:UCLA-LIVEST 项目
- 批准号:
8294044 - 财政年份:2011
- 资助金额:
$ 15.53万 - 项目类别:
ENHANCING OUTCOMES IN YOUNG BREAST CANCER SURVIVORS: A PROGRAM OF THE UCLA-LIVEST
提高年轻乳腺癌幸存者的治疗效果:UCLA-LIVEST 项目
- 批准号:
8497454 - 财政年份:2011
- 资助金额:
$ 15.53万 - 项目类别:
VITAMIN D IN BREAST CANCER: A CROSS-SECTIONAL OBSERVATIONAL STUDY IN RECENTLY DI
维生素 D 在乳腺癌中的作用:近期 DI 的一项横断面观察研究
- 批准号:
8167136 - 财政年份:2009
- 资助金额:
$ 15.53万 - 项目类别:
THE UCLA FAMILIAL CANCER REGISTRY AND GENETIC EVALUATION PROGRAM
加州大学洛杉矶分校家族癌症登记和基因评估计划
- 批准号:
8167123 - 财政年份:2009
- 资助金额:
$ 15.53万 - 项目类别:
相似国自然基金
农产品出口区域化管理对企业和农户的行为决策及经济绩效影响研究
- 批准号:72373067
- 批准年份:2023
- 资助金额:41 万元
- 项目类别:面上项目
区域压缩对非线性噪声驱动的随机偏微分方程动力学行为影响的研究
- 批准号:12371178
- 批准年份:2023
- 资助金额:43.5 万元
- 项目类别:面上项目
长三角地区氯化石蜡的土壤—大气界面交换行为及区域环境影响研究
- 批准号:42307512
- 批准年份:2023
- 资助金额:30.00 万元
- 项目类别:青年科学基金项目
面向廊道式TOD(C-TOD)的巨型城市区域轨道交通对居民出行行为时空特征的影响机制研究
- 批准号:42201210
- 批准年份:2022
- 资助金额:30.00 万元
- 项目类别:青年科学基金项目
时间变区域上三类发展方程解的长时间动力学行为研究
- 批准号:12201142
- 批准年份:2022
- 资助金额:30.00 万元
- 项目类别:青年科学基金项目
相似海外基金
Implementation of Innovative Treatment for Moral Injury Syndrome: A Hybrid Type 2 Study
道德伤害综合症创新治疗的实施:2 型混合研究
- 批准号:
10752930 - 财政年份:2024
- 资助金额:
$ 15.53万 - 项目类别:
Implementing SafeCare Kenya to Reduce Noncommunicable Disease Burden: Building Community Health Workers' Capacity to Support Parents with Young Children
实施 SafeCare Kenya 以减少非传染性疾病负担:建设社区卫生工作者支持有幼儿的父母的能力
- 批准号:
10672785 - 财政年份:2023
- 资助金额:
$ 15.53万 - 项目类别:
Novel application of pharmaceutical AMD3100 to reduce risk in opioid use disorder: investigations of a causal relationship between CXCR4 expression and addiction vulnerability
药物 AMD3100 降低阿片类药物使用障碍风险的新应用:CXCR4 表达与成瘾脆弱性之间因果关系的研究
- 批准号:
10678062 - 财政年份:2023
- 资助金额:
$ 15.53万 - 项目类别:
The Causal Impact of Poverty Reduction on Housing Conditions of Low-Income, U.S. Children and the Role of Housing and Neighborhood Ecosystems on Young Children's Healthy Development
减贫对美国低收入儿童住房条件的因果影响以及住房和邻里生态系统对幼儿健康发展的作用
- 批准号:
10678527 - 财政年份:2023
- 资助金额:
$ 15.53万 - 项目类别: