P and F Program

P 和 F 计划

• 批准号: 10392982
• 负责人: JANE E REUSCH
• 金额: $ 34.4万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-04-01 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10392982
• 关键词: Award; Biological; Clinical Sciences; Collaborations; Colorado; Communities; Consultations; Data; Diabetes Mellitus; Discipline; Evaluation; Fostering; Funding; Goals; Grant; Home; Individual; Institution; Investigation; Knowledge; Leadership; Medical; Mentorship; Modeling; Organoids; Physiological; Process; Publications; Research; Research Personnel; Research Project Grants; Talents; Training; Translational Research; United States National Institutes of Health; Universities; Vocational Guidance; career; diabetes risk; high risk; immunoregulation; improved; innovation; member; novel; programs; recruit; sex; tool

PILOT AND FEASIBILITY PROGRAM SUMMARY/ABSTRACT The Pilot and Feasibility Program (P&F) is a key component of the UC Denver DRC that will allow DRC leadership to: 1) recruit new talent into diabetes research, 2) attract established investigators from other disciplines into diabetes-related scientific pursuits, and 3) support innovative/high-risk diabetes research projects. Our priority is the support of young, newly independent investigators at the University of Colorado Anschutz Medical Campus (UC AMC), and its affiliated institutions, who are embarking on diabetes research careers, but have yet to attain substantial funding. In addition, the UC Denver DRC P&F Program is an important means of promoting interdisciplinary diabetes research by fostering collaboration between DRC members and improving university-wide interactions between DRC members and other UC Denver NIH Centers or Dean’s Initiatives. The P&F program will also serve as a mechanism to increase the diversity of the UC AMC diabetes research community and its research portfolio. We will achieve these goals through the following specific aims: AIM 1: To establish a transparent and streamlined process for grant solicitation, scientific review, funding, project guidance/management, and progress assessment. AIM 2: To enhance the UC AMC diabetes research community and diversify its innovative research portfolio by providing funding to: a) early career diabetes investigators who lack substantial research funding; b) established investigators from other fields that intend to apply their knowledge and expertise to investigation of diabetes- related topic(s); c) established diabetes investigators who propose innovative, high-risk projects that deviate from their current funded research programs, and that would be unlikely to be funded through the usual granting agencies without compelling preliminary data; d) develop novel models (i.e. organoids) to examine unique physiological targets such as sex as a biological variable and immunomodulation. AIM 3: To provide career guidance and a scientific home for P&F funded investigators. AIM 4: To formally evaluate the impact of the UC Denver DRC P&F Program on individual grant recipients, as well as on the UC AMC diabetes research community as a whole.

飞行员和可行性计划 摘要/摘要 飞行员和可行性计划（P＆F）是UC Denver DRC的关键组成部分，它将允许DRC 领导：1）将新人才招募到糖尿病研究中，2）吸引其他其他研究人员 学科进入与糖尿病相关的科学追求，3）支持创新/高风险糖尿病研究 项目。我们的首要任务是科罗拉多大学的年轻，新独立的调查员的支持 Anschutz医疗校园（UC AMC）及其关联机构正在进行糖尿病研究 职业，但尚未获得大量资金。此外，UC Denver DRC P＆F计划是重要的 是指促进跨学科糖尿病研究，通过促进DRC成员与 改善DRC成员与其他UC Denver NIH中心或Dean的范围内的互动 倡议。 P＆F计划还将作为增加UC AMC糖尿病多样性的机制 研究社区及其研究组合。我们将通过以下特定目标来实现这些目标： 目标1：建立透明且简化的流程，以进行授予招标，科学审查，资金，项目 指导/管理和进度评估。 目标2：增强UC AMC糖尿病研究界，并通过 向以下资金提供资金：a）缺乏大量研究资金的早期职业糖尿病调查人员； b）成立 来自其他领域的调查人员打算将其知识和专业知识应用于糖尿病的调查 - 相关主题； c）成立的糖尿病调查人员，他们提出了偏离创新的高风险项目 从目前的资助研究计划中，这不太可能通过通常的授予来资助 机构没有引人注目的初步数据； d）开发新型模型（即器官）以检查独特的模型 诸如性变量和免疫调节之类的物理靶标。 目标3：为P＆F资助的调查人员提供职业指导和科学家。 目标4：正式评估UC Denver DRC P＆F计划对单个赠款接收者的影响，作为 以及整个UC AMC糖尿病研究社区。