Improving physical function and quality of life in older adults with prediabetes utilizing interactive small-group resistance training through video conference technology

通过视频会议技术利用交互式小组阻力训练，改善患有前驱糖尿病的老年人的身体功能和生活质量

• 批准号: 10384566
• 负责人: Eric Levitan
• 金额: $ 30万
• 依托单位: IMPACTIV, INC.
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-15 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10384566
• 关键词: Accountability; Adherence; Adult; Affect; Age; Behavioral; Benchmarking; Body Weight; Chronic Disease; Client; Clinical Trials; Cognition; Cognitive; Communities; Computer software; Couples; Custom; Databases; Elderly; Electronic Mail; Elements; Equilibrium; Exercise; Exertion; Family; Family member; Feedback; Friends; Glucose; Glycosylated hemoglobin A; Goals; Health; Hour; Independent Living; Individual; Internet; Joints; Knee; Location; Lower Extremity; Measures; Monitor; Motivation; Motor; Movement; Muscle; Muscle function; Muscular Atrophy; Non-Insulin-Dependent Diabetes Mellitus; Outcome; Participant; Performance; Persons; Phase; Physical Function; Physiological; Pilot Projects; Prediabetes syndrome; Quality of life; Sampling; Silver; Small Business Innovation Research Grant; Social Network; Social support; Supervision; Support System; System; Technology; Testing; Thinness; Time; Training; Training Programs; Videoconferencing; Waiting Lists; Woman; Work; aging in place; arm; base; cognitive task; commercialization; design; digital; effectiveness evaluation; evidence base; exercise program; experience; fall risk; fitness; healthy aging; improved; in vivo; innovation; member; mobile application; muscle form; novel; pandemic disease; prevent; primary outcome; prototype; psychologic; sarcopenia; satisfaction; secondary outcome; sedentary; social engagement; strength training; success; technological innovation; usability; virtual; walking speed; young adult

Vivo is a virtual small group exercise program designed for adults 55 and over that is unique in the increasingly popular digital fitness market. Vivo offers 3 key market differentiators: 1) a personalized and individualized live training experience with feedback from a certified trainer, 2) a community of older adult exercisers which enhances motivation and social support, and increase accountability and fun, and 3) the Vivo training experience focuses on improving physical function using performance feedback, goal setting, and a system to measure perceived exertion. Most older adults experience a 30% loss in muscle mass between ages 50–70. Resistance training is the most effective strategy for improving both muscle mass and function and managing sarcopenia. Vivo’s programming is based on the scientific evidence that even in the absence of chronic disease, resistance training that is customized to meet the individual’s needs and level of functioning is a feasible and evidence-based approach to improve physical function, regulate glucose handling, reduce the risk for falls, and prolong independent living and aging in place. To date 92 people have participated in Vivo (age range 44-93). In our pilot study of 34 older adults (74% women; mean age 70.9 y; range 60-84y) after 8 weeks of participating in Vivo with a certified trainer (average of 12 hours of training per person) we observed +25.8% improvement in upper body strength as measured by the 30 second arm curl test; +25.9% improvement in lower body strength as measured by the 30 second chair stand test; and +28% improvement in endurance as measured by the 2-minute knee raise test. The aims for this SBIR FastTrack are as follows: Phase I Aim 1: Evaluate the acceptability, feasibility, and fidelity of current Vivo prototype in sedentary older adults with prediabetes Milestone 1: Assess a) attendance, benefits and barriers/facilitators of participation; b) ease of use; and c) overall satisfaction. Milestone 2: Assess trainer fidelity. Aim 2 : Design and develop a multifunctional platform prototype for Vivo 2.0 Milestone 1: Create functional specifications of the client-centered approach (results, goals, adherence, upcoming workouts), and social engagement and support. Milestone 2: Develop a clickable prototype of the platform. Phase II Aim 1: Design and build the Vivo 2.0 platform – a unified web/mobile application. Milestone 1: Assess prototype usability. Milestone 2: Iterate the design on the software and hardware to increase usage, accuracy and usability. Milestone 3: Develop and test a minimum viable software product based on the new prototype and functional design to include a mobile front-end and web front-end app and a backend database. Aim 2: Conduct a RCT to determine effectiveness of Vivo 2.0 v. wait list control. Primary outcomes will be change in lower extremity strength after 12 weeks measured by the number of chair stands in 30 seconds and average glycemic level (HgA1c). Secondary outcomes will include improvements in quality of life, and effect of adherence and social engagement on physical function outcomes.

Vivo是一项虚拟的小组锻炼计划 越来越流行的数字健身市场。 Vivo提供3个主要市场差异化：1）个性化和 通过认证培训师的反馈，2）老年人社区的个性化现场培训经验 增强动力和社会支持，增加问责制和娱乐的锻炼者，以及3）体内 培训经验的重点是使用绩效反馈，目标设定和A改善身体功能 测量感知劳累的系统。大多数老年人在年龄之间的肌肉质量损失30％ 50–70。抵抗训练是改善肌肉质量和功能的最有效策略， 管理肌肉减少症。 Vivo的编程基于科学证据，即即使没有 慢性疾病，量身定制以满足个人需求和功能水平的抵抗训练是 一种可行且基于证据的方法来改善身体机能，调节葡萄糖处理，减少 跌倒的风险，并延长独立的生活和衰老。迄今为止有92人参加了体内 （年龄范围44-93）。在我们对34名老年人（74％女性；平均年龄70.9 y;范围60-84Y）的试点研究中 我们观察到的经过认证的培训师（平均每人12小时的培训）参加体内数周 通过30秒臂卷曲测试测量的上半身强度提高了25.8％； +25.9％ 通过30秒椅子测试衡量的下半身力量的提高；和 + +28％改善 通过2分钟的膝盖升高测试来测量耐力。 SBIR FastTrack的目的如下： 第一阶段目标1：评估当前体内原型久坐的可接受性，可行性和保真度 具有糖尿病前期里程碑的老年人1：评估a）出席，福利和障碍/促进者 参与； b）易用性； c）总体满意度。里程碑2：评估教练保真度。 目标2 ： 设计 并为Vivo 2.0里程碑开发多功能平台原型1：创建功能规范 以客户为中心的方法（结果，目标，依从性，即将进行的锻炼）以及社会参与和 支持。里程碑2：开发平台的可点击原型。第二阶段目标1：设计和构建 Vivo 2.0平台 - 统一的Web/移动应用程序。里程碑1：评估原型可用性。里程碑2： 迭代软件和硬件上的设计，以提高使用，准确性和可用性。里程碑3： 根据新的原型和功能设计开发和测试最低可行的软件产品 包括移动前端和Web前端应用程序以及后端数据库。目标2：进行RCT 确定Vivo 2.0 v。等待列表控制的有效性。主要结果将是下肢的变化 12周后通过椅子的数量在30秒内测量的强度，平均血糖水平 （HGA1C）。次要结果将包括改善生活质量以及依从性和社会的影响 参与身体功能结果。