Anti-viral Active Air-Purifying Respirator with Photocatalytic Microreactor to Prevent Airborne Diseases

带光催化微反应器的抗病毒主动空气净化呼吸器可预防空气传播疾病

• 批准号: 10385625
• 负责人: M Arifur Rahman
• 金额: $ 24.35万
• 依托单位: HAWAI'I INNOVATION LABORATORY, INC.
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10385625
• 关键词: Anti; viral; Active; Air; Purifying

Project Summary/Abstract The potential for an epidemic or pandemic caused by a high-impact respiratory pathogen is increasing. Studies prior to the COVID-19 outbreak show that the frequency of outbreaks of newly emerging diseases rose, which has exacerbated since the pandemic started. Respiratory protective masks are used whenever airborne contaminants such as dust, fumes, smoke, and mists are present in the air. The contaminants also include airborne bacteria, viruses, and fungi. Currently, most commercially available untethered protective masks are designed for surgical or industrial safety and may provide adequate protection from airborne contaminants but do so through particle filtering. Therefore, most masks do not kill the pathogens to protect the wearers. Hence, while using an active respirator, the filtered pathogens, which are alive and infectious, may enter the respiratory tract overtime or spread by touch. The current active respirators are bulky, heavy, and designed for 2-4 hours of use. In brief, the protective masks are not designed for prolonged daily use by untrained users. Until the outbreak of COVID-19, the necessity of an anti-pathogenic wearable respirator was not as significant as it is now. This COVID-19 has exposed our lack of preparedness in providing a safe working environment for the frontline workers during the respiratory pandemic. Most current protective respirators address only part of the desired solution. A working solution needs to combine all the critical requirements, such as high filtration (≥ 99%) for nanometer-scale particles, pathogens-neutralization, moisture dissipation, eco-friendliness, and comfortable prolonged use. The proposed R&D effort addresses a wearable anti-pathogenic respirator's critical need for prolonged use by trained or untrained users. We propose designing and developing an active, untethered, anti- pathogen full-face breathing mask with an integrated photocatalytic microreactor that can neutralize all microorganisms, including viruses SARS-CoV-2. Although the proposed system contains all the components of a portable respirator, the components are miniaturized and integrated into a full-face mask. Hence, the system is referred to as a full-face mask in this proposal. The proposed full-face mask intakes surrounding air filters out particles as small as 100 nm (size of a single SARS-CoV-2 viral particle), passes the air through an integrated photocatalytic microreactor killing all the microorganisms, and volatile organic chemicals (VOCs), and supply clean air to the user. The mask also works as a defense against the threat of contamination of ventilation systems by bioterrorism. The mask is completely untethered and designed to run for 8-10 hours with a single charge. The active-powered mask can save the wearer from airborne pathogens while maintaining visibility and comfort.

项目概要/摘要 由高影响呼吸道病原体引起流行病或大流行的可能性正在增加。 在 COVID-19 爆发之前表明，新出现的疾病爆发的频率上升，这 自大流行开始以来，情况一直在恶化，只要在空中飞行，就需要佩戴呼吸防护口罩。 空气中存在灰尘、烟雾、烟雾和薄雾等污染物。 目前，大多数市售的无线防护口罩都是空气传播的细菌、病毒和真菌。 专为手术或工业安全而设计，可提供足够的保护，防止空气中的污染物，但 因此，大多数口罩不会杀死病原体来保护佩戴者。 使用主动式呼吸器时，过滤后的活的且具有传染性的病原体可能会进入呼吸道 目前的主动式呼吸器体积大、重，设计时可使用 2-4 小时。 简而言之，在疫情爆发之前，防护口罩不适合未经培训的使用者长时间日常使用。 在 COVID-19 爆发期间，抗病可穿戴式呼吸器的必要性并不像现在那么重要。 COVID-19 暴露了我们在为前线提供安全工作环境方面缺乏准备 大多数当前的防护呼吸器只能满足呼吸道大流行期间的部分要求。 有效的解决方案需要结合所有关键要求，例如高过滤（≥ 99%）。 纳米级颗粒，中和病原体，排湿，环保，舒适 拟议的研发工作解决了可穿戴式抗病原呼吸器的关键需求。 我们建议设计和开发一种主动的、不受束缚的、抗干扰的产品。 带有集成光催化微反应器的病原体全脸呼吸面罩，可以中和所有病原体 尽管所提出的系统包含病毒 SARS-CoV-2 的所有组件。 便携式呼吸器的组件被小型化并集成到全面罩中，因此，该系统。 在本提案中，提议的全面罩进气口周围的空气过滤器被称为全面罩。 小至 100 nm 的颗粒（单个 SARS-CoV-2 病毒颗粒的大小），使空气通过集成的 光催化微反应器杀死所有微生物和挥发性有机化学物质（VOC），并供应 为用户提供洁净的空气，该面罩还可以防御通风系统污染的威胁。 该面罩完全不受束缚，一次充电可运行 8-10 小时。 主动供电面罩可以保护佩戴者免受空气中病原体的侵害，同时保持能见度和舒适度。