SToP Cancer SPORE: Developmental Research Program

STOP Cancer SPORE：发展研究计划

• 批准号: 10334088
• 负责人: ALBERT Sidney BALDWIN
• 金额: $ 12.06万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-16 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10334088
• 关键词: Applications Grants; Area; Award; Basic Cancer Research; Biomedical Engineering; Budgets; Cancer Control; Cellular biology; Clinical Research; Collaborations; Development; Early Diagnosis; Early treatment; Epigenetic Process; Evaluation; Extramural Activities; Faculty; Foundations; Funding; Genetic; Goals; Historically Black Colleges and Universities; Immunology; Immunotherapy; Incidence; Institution; Lead; Leadership; Malignant Neoplasms; Malignant neoplasm of pancreas; Mission; Modeling; Monitor; North Carolina; Pancreas; Participant; Peer Review; Population Research; Population Study; Program Research Project Grants; Program Reviews; Publications; Research; Research Personnel; Research Support; Resources; Review Committee; Signal Transduction; Sister; Technology; Testing; Therapeutic; Time; Translational Research; Underrepresented Minority; United States National Institutes of Health; Universities; Woman; Work; anticancer research; base; cancer cell; cancer imaging; cancer prevention; cancer therapy; career; career development; drug development; experience; flexibility; improved outcome; innovation; insight; meetings; mortality; novel therapeutic intervention; pre-clinical; programs; success; translational goal; translational potential; tumor immunology

DEVELOPMENTAL RESEARCH PROGRAM: ABSTRACT The Developmental Research Program (DRP) is critical to the UNC SToP Cancer SPORE mission to advance basic understanding of pancreatic cancer development and progression, and to develop new therapeutic approaches. The overarching goal of the SPORE DRP is to identify and provide research support for innovative projects that provide key insight into critical areas of pancreatic cancer research. Funded DRP projects should provide compelling evidence of potential to develop into full projects within the SPORE and/or to be funded by peer-reviewed federal (NIH/NCI, DOD) or foundation resources. Each year with institutional support, the DRP intends to fund up to three projects of approximately $100,000, with a second year of funding dependent on progress in the first year. Budget flexibility will be built in if the senior leadership determines that a project is particularly promising. RFAs for the UNC SToP Cancer SPORE developmental projects will be offered once a year, with proposals solicited from UNC, and our sister institutions which include NC State University (NCSU) and NC Central University (NCCU, a historically black college/university). The DRP Review Committee (DRPRC) will review applications focused on pancreatic cancer basic research (such as cancer cell signaling, cell biology, and genetics); translational research (biomedical engineering [BME], cancer imaging, cancer immunology/immunotherapy, and therapeutic approaches); and population research, including cancer prevention and control.

发展研究计划：摘要 发展研究计划（DRP）对于UNC停止癌症孢子任务至关重要 对胰腺癌发展和进展的基本了解，并发展新的治疗 方法。孢子DRP的总体目标是识别和为创新提供研究支持 为胰腺癌研究的关键领域提供重要洞察力的项目。资助的DRP项目应该 提供令人信服的证据，证明有潜力发展为孢子内的完整项目和/或由 同行评审的联邦（NIH/NCI，国防部）或基金会资源。每年在机构支持的情况下，DRP 打算为多达100,000美元的三个项目提供资金，第二年的资金取决于 第一年的进展。如果高级领导确定项目，将建立预算灵活性 特别有前途。 UNC停止癌症孢子发育项目的RFA将一次提供一次 一年，由UNC提出的提案和我们的姊妹机构，包括NC州立大学 （NCSU）和NC中央大学（NCCU，历史悠久的黑人学院/大学）。 DRP评论 委员会（DRPRC）将审查针对胰腺癌基础研究的申请（例如癌症 细胞信号，细胞生物学和遗传学）；翻译研究（生物医学工程[BME]， 癌症成像，癌症免疫学/免疫疗法和治疗方法）；和人口 研究，包括预防癌症和控制。