The Administrative Core

行政核心

• 批准号: 10327945
• 负责人: JAY A NELSON
• 金额: $ 13.09万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-15 至 2027-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10327945
• 关键词: Adjuvant; Binding; Communication; Complex; Contracts; Cytomegalovirus; Decision Making; Doctor of Philosophy; Emerging Communicable Diseases; Ensure; Environment; Fostering; Goals; Grant; Hematopoietic stem cells; Human; Institution; International; Maintenance; Molecular; Monitor; National Institute of Allergy and Infectious Disease; Office of Administrative Management; Pacific Northwest; Pathogenesis; Principal Investigator; Reporting; Research; Signal Pathway; Signal Transduction; Time; United States National Institutes of Health; Viral; Virus Latency; biodefense; cell growth regulation; collaborative environment; data dissemination; data resource; data sharing; experience; meetings; member; programs

SUMMARY - ADMINISTRATIVE CORE (CORE C) The overall goal of this PPG is to elucidate the molecular mechanisms of HCMV regulation of cellular signaling in the establishment and maintenance of viral latency and viral reactivation. To meet this goal, we have assembled an extraordinary group of virologists who will collaborate in five highly interactive projects and two scientific cores. The Program Director (PD) and Principal Investigator of the Administrative Core is Jay Nelson, Ph.D., who is a senior molecular virologist with extensive experience studying the molecular interaction of cytomegaloviruses and their host environment. Dr. Nelson will be co-leading this program with Dr. Andrew Yurochko, who is an international expert in the study of Human Cytomegalovirus dissemination and pathogenesis. They will be assisted by an exceptional administrative team that has a proven track record in administering and managing large, complex grants and contracts such as the Pacific Northwest Regional Center of Excellence in Biodefense and Emerging Infectious Diseases (PNWRCE), two NIAID Adjuvant Discovery Contracts, and the ongoing original P01 on which this renewal proposal is built upon. The significant experience of this group with the organization, reporting and communications associated with the successful administration of multi-institutional research programs will be invaluable in ensuring a successful management of this PPG. The Administrative Core will serve as a hub for administration, communication and monitoring for the entire program. The core will serve all projects and all scientific cores, and it will interact with all institutions involved in this program. The Administrative Core will also serve as a central point of interaction with NIH Program. Finally, the administrative team will assist the program director in ensuring regular and timely communication among the members of this consortium as well as reporting to NIAID program.

摘要 - 行政核心（核心C） 该PPG的总体目标是阐明细胞信号的HCMV调节的分子机制 在病毒潜伏期和病毒重新激活的建立和维持中。为了实现这个目标，我们有 组建了一个非凡的病毒学家组，他们将在五个高度互动的项目中合作，两个 科学核心。计划主任（PD）和行政核心的首席调查员是Jay Nelson， 博士学位，他是一位高级分子病毒学家，拥有丰富的研究分子相互作用的经验 巨细胞病毒及其宿主环境。尼尔森博士将与安德鲁博士共同领导该计划 尤洛霍科（Yurochko），是人类巨细胞病毒传播研究和 发病。他们将得到一个杰出的行政团队的协助，该团队在 管理和管理大型，复杂的赠款和合同，例如太平洋西北地区 生物形式和新兴传染病（PNWRCE）的卓越中心，两个NIAID佐剂 发现合同以及正在进行的原始P01建立了该提案。重要的 该小组与组织，与成功相关的报告和沟通的经验 多机构研究计划的管理对于确保成功的管理将是无价的 这个ppg。行政核心将作为管理，沟通和监视的枢纽 整个程序。核心将为所有项目和所有科学核心服务，并将与所有机构互动 参与此程序。行政核心还将成为与NIH互动的中心点 程序。最后，行政团队将协助计划主任确保常规和及时 该财团成员之间的沟通以及向NIAID计划报告。