Developing data science solutions to mitigate the health impacts of climate change in Africa: the HE2AT Center

开发数据科学解决方案以减轻非洲气候变化对健康的影响：HE2AT 中心

基本信息

批准号：
10314149
负责人：
Matthew Francis Chersich
金额：
$ 130万
依托单位：
WITS HEALTH CONSORTIUM (PTY), LTD
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-15 至 2026-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10314149
关键词：
Address Adopted Africa Africa South of the Sahara African Air Basic Science Behavioral Behavioral Sciences Biometry Birth Weight Centers for Disease Control and Prevention (U.S.)Characteristics Climate Climatology Clinical Clinical Medicine Collaborations Communities Computers Dangerousness Data Data Analyses Data Science Data Scientist Data Sources Development Disease Ecosystem Elements Environmental Exposure Environmental Health Event Future General Population Geography Goals Government Health Health Sciences Heat Waves Housing Individual Industrialization Industry Influentials Institution Ivory Coast Knowledge Link Low income Machine Learning Morbidity - disease rate Outcome Output Participant Pilot Projects Planets Policies Pre-Eclampsia Pregnant Women Premature Birth Preparation Public Health Research Research Activity Research Priority Research Project Grants Resources Risk Risk Factors Scientist Series Social Sciences Software Design South Africa Specificity System Techniques Technology Temperature Testing Time Training Training Support United States Universities Vertebral column Vulnerable Populations Weather Work base built environment burden of illness career climate change climate data climate impact cohort complex data computer science data ecosystem data management data repository data reuse digital doctoral student extreme heat global temperature hazard health data high risk high risk population innovation interest machine learning algorithm maternal outcome mortality neonatal outcome neonate programs prospective response risk prediction social statistics urban area urban setting

项目摘要

HE2AT Center Overall - Project summary/abstract The world's climate is changing rapidly, with global temperatures having risen more than 1°C since the industrial revolution, and a further 0.5°C increase is likely by 2040. Heat waves and rising temperatures have major, though underappreciated, health implications, particularly for vulnerable populations in low-income settings. The overarching objective of the Heat and Health African Transdisciplinary Center (HE2AT Center) is to develop innovative solutions to mitigate the health impacts of climate change in Africa. The consortium of academic and non-academic partners is drawn from across sub-Saharan Africa and from the United States, and constitutes a transdisciplinary group, including heat physiologists, biomedical and climate content experts, public health practitioners, social-behavioral scientists as well as statisticians, and computer and data scientists. The Center will systematically develop a data ecosystem containing biomedical data, integrated with weather, air quality and other environmental data, and other geospatial data within two existing highly- complementary data platforms (IBM-PAIRS and the University of Cape Town). Over five years we will implement two Research Projects and 10-12 Pilot Projects, all streamlined and supported by the Administration, Data Management and Analysis, and Training and Engagement Cores. The first Project will implement an innovative data science approach to characterize the clinical outcomes of heat exposure in pregnant women and neonates. We will reuse data from cohorts and trials among pregnant women and neonates conducted across sub-Saharan Africa since the year 2000. Data from systematically identified studies will be integrated in an Individual Participant Data platform from data repositories and data owners. Then, analyses of relationships between heat exposure and outcomes (preterm birth, birth weight and pre- eclampsia) will inform quantification of heat-related disease burden. Finally, taking all findings together, we will pilot a district-level climate change indicator, the first of its kind. The second Project assesses the burden of heat-related morbidity in vulnerable urban settings using geospatial and heat hazard analyses in Abidjan, Cote d'Ivoire and Johannesburg, South Africa. This Project uses more complex data and data sources on the built environment and topography, for example, to assess heat-health impacts, and how these vary across urban geographies. Activities will inform development of an Early Warning System, including a digital App that delivers information to people on their forecasted risks of heat-health disease, based on their individualized risk profile, as determined by a machine learning algorithm which takes into account weather conditions, individual characteristics, geolocation and other factors that drive risk. These systems are a central element in heatwave responses, allow for adequate preparations for heat events, which is especially important for vulnerable groups and industry. We will collaborate closely with other Hubs and parts of the DS-I Africa consortium, supporting them to incorporate climate data within their research activities, and vice versa.

HE2AT中心整体 - 项目摘要/摘要世界的气候正在迅速变化，自从全球温度增长超过1°C以来工业革命，另外0.5°C的增加可能到2040年。热浪和温度升高具有主要的，尽管被低估了健康的影响，特别是对于低收入的脆弱人群设置。非洲跨学科中心（HE2AT中心）的总体目标是开发创新的解决方案来减轻非洲气候变化的健康影响。财团的学术和非学术伙伴来自撒哈拉以南非洲以及美国，并构成一个跨学科群体，包括热生理学家，生物医学和气候含量专家，公共卫生从业人员，社会行为科学家以及统计学家以及计算机和数据科学家。该中心将系统地开发一个包含生物医学数据的数据生态系统，并集成在两个现有的高度高度 - 完全数据平台（IBM对和开普敦大学）。五年来，我们将实施两个研究项目和10-12个试点项目，所有这些项目都简化和支持管理，数据管理和分析以及培训和参与核心。第一个项目将实施创新的数据科学方法，以表征热暴露的临床结果孕妇和新生儿。我们将从孕妇和孕妇中的审判中重复使用数据自2000年以来，在撒哈拉以南非洲进行的新生儿。研究将从数据存储库和数据所有者中整合到单个参与者数据平台中。然后，分析热暴露与结局之间的关系（早产，出生体重和预 - ECLAMPSIA）将告知与热有关的疾病伯恩的量化。最后，将所有发现一起，我们将试点地区气候变化指标，第一个指标。第二个项目评估了燃烧使用地理空间和热危害分析的脆弱城市环境中的热有关发病率，cote D'Ivoire和南非约翰内斯堡。该项目使用更复杂的数据和数据源例如，环境和地形来评估热健康的影响，以及这些影响如何在城市中变化地理。活动将为预警系统的开发提供信息，包括一个数字应用根据其个性化风险，向人们提供有关其预测的热健康疾病风险的信息轮廓，由机器学习算法确定，该算法考虑了天气状况特征，地理位置和其他驱动风险的因素。这些系统是热浪中的核心元素响应，允许为热事件做足够的准备，这对脆弱的群体尤为重要和行业。我们将与DS-I非洲财团的其他枢纽和部分密切合作，并支持他们将气候数据纳入其研究活动中，反之亦然。