Iowa Cochlear Implant Clinical Research Center VII

爱荷华州人工耳蜗临床研究中心七

基本信息

批准号：
10308173
负责人：
RUTH A BENTLER
金额：
$ 30.52万
依托单位：
UNIVERSITY OF IOWA
依托单位国家：
美国
项目类别：
财政年份：
1985
资助国家：
美国
起止时间：
1985-09-09 至 2023-05-14
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10308173
关键词：
Acoustics Affect Anatomy Auditory Behavior Cellular Phone Characteristics Classification Clinical Research Cochlear Implants Cochlear implant procedure Cognition Communication Data Decision Making Detection Ear Ecological momentary assessment Ecology Environment Environmental Risk Factor Exhibits Goals Health Healthcare Hearing Hearing Aids Heterogeneity Human Hybrids Impairment Implant Improve Access In Situ Individual International Intervention Iowa Laboratories Life Style Literature Measurement Mental Depression Music Natural Sciences Noise Outcome Outcome Measure Participant Patient Self-Report Perception Personality Physiological Physiology Policies Population Predictive Factor Principal Investigator Procedures Quality of life Questionnaires Rehabilitation therapy Research Residual state Role Signal Transduction Social Environment Social Sciences Social isolation Socialization Sound Localization Speech Speech Perception Speech Sound Standardization Stimulus System Time Work base built environment design disability experience genetic information group intervention hearing impairment improved instrument interest intervention effect lexical processing novel preservation primary outcome programs social speech in noise success tool

项目摘要

Program Director/Principal Investigator (Last, First, Middle): Gantz, Bruce J. PROJECT SUMMARY – PROJECT 1 The past 35 years of cochlear implant (CI) research have focused on outcomes primarily related to speech perception. Candidacy recently has extended into the less severely impaired population due to newer, shorter implants, including hybrid (acoustic-plus-electric) designs. The potential for improvement/change in domains other than speech perception can inform both policy and rehabilitative decision-making. Human ecology describes the relationship between humans and their natural, social, and built environments. This concept considers that human behaviors must be studied from both the social and natural science vantage points. In hearing health care, success with intervention is as much related to the anatomy/physiology of the individual as it is to the environmental and personal (i.e., ecological) factors that make each individual unique from the next. The overall goal of this project is to determine the impact of intervention on user's hearing-related functions and disability in their natural environments (i.e., real-world outcomes) and to clarify what ecological factors, as well as perceptual factors, affect these real-world outcomes. To date most cochlear implant (CI) research has focused on determining the effect of anatomical and physiological factors on laboratory outcomes, such as speech perception. We recognize, however, that the real-world outcomes exhibit great heterogeneity, which is likely due, in part, to the broader range of environmental and personal contextual (i.e., ecological) underpinnings in the hearing impaired population. As has been the case with hearing aids (HA), much variance can be accounted for by examining individual ecological factors. Very little is understood about (1) the characteristics of ecological factors of the CI population, (2) the influence that ecological factors have on the heterogeneity of real-world outcomes of this population, and (3) how this influences changes over time. With the expanded indications for CI quantifying the ecological factors that parlay into real-world outcomes in CI is critical because real-world outcomes ultimately determine societal burden and policy. Furthermore, because traditional retrospective self-reported outcome measures are often subject to recall bias, we will, in addition to standardized questionnaires and a data-logging feature on the processors, use a smartphone-based ecological momentary assessment (EMA) system to capture users' real-time experiences in situ (i.e., in natural environment). This will allow for measurement of the characteristics of listening environments in addition to subjective assessment of listening difficulty/ease. Two Aims have been designed to study the influence of ecological factors have on outcomes of listeners with a CI. Aim 1. To characterize environmental factors that are relevant to listening and communication for participants in each intervention group (Aim 1A) and to determine the effect of intervention on these factors (Aim 1B). Aim 2. To document the effect of intervention on real-world outcomes (Aim 2A) and determine to what extent environmental, personal, and perceptual factors moderate those outcomes (Aim 2B) over time (Aim 2C).

项目总监/首席研究员（最后、第一、中间）：Gantz, Bruce J. 项目摘要 – 项目 1 过去 35 年的人工耳蜗 (CI) 研究主要集中于与言语相关的结果由于更新、时间较短，候选资格最近已扩展到受影响较轻的人群。植入物，包括混合（声加电）设计领域的改进/改变的潜力。除了言语感知之外，其他因素还可以为政策和康复决策提供信息。人类生态学描述了人类与其自然、社会和建筑环境之间的关系。这一概念认为人类行为必须从社会科学和自然科学两方面来研究在听力保健中，干预的成功与解剖学/生理学密切相关。个体的环境和个人（即生态）因素使每个个体该项目的总体目标是确定干预对用户的影响。自然环境中的听力相关功能和残疾（即现实世界的结果）并澄清哪些生态因素以及感知因素影响这些现实世界的结果。迄今为止，大多数人工耳蜗 (CI) 研究都集中在确定解剖学和人工耳蜗的影响上。然而，我们认识到，生理因素对实验室结果的影响，例如言语感知。现实世界的结果表现出巨大的异质性，这可能部分是由于更广泛的范围听力障碍人群的环境和个人背景（即生态）基础。助听器 (HA) 就是这种情况，通过检查个人可以解释很大的差异对（1）CI生态因素的特征知之甚少。人口，（2）生态因素对其真实世界结果异质性的影响人口，以及（3）随着时间的推移，随着 CI 量化适应症的扩大，这种影响如何变化。在 CI 中影响现实世界结果的生态因素至关重要，因为现实世界的结果最终此外，由于传统的回顾性自我报告结果。措施通常会受到回忆偏差的影响，除了标准化问卷和数据记录之外，我们还会处理器上的功能，使用基于智能手机的生态瞬时评估（EMA）系统捕获用户在现场（即在自然环境中）的实时体验，这将允许测量。除了听力难度/难易程度的主观评估之外，还包括听力环境的特征。目的是研究生态因素对 CI 听众结果的影响。目标 1. 描述与参与者倾听和沟通相关的环境因素每个干预组（目标 1A）并确定干预对这些因素的影响（目标 1B）。目标 2. 记录干预对现实世界结果的影响（目标 2A）并确定影响程度随着时间的推移（目标 2C），环境、个人和感知因素会调节这些结果（目标 2B）。