Developing and Testing the Opioid Rapid Response System

开发和测试阿片类药物快速反应系统

• 批准号: 10303574
• 负责人: Michael Hecht
• 金额: $ 4.22万
• 依托单位: REAL PREVENTION, LLC
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-30 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10303574
• 关键词: Address; Area; Certification; Cessation of life; Cluster randomized trial; Collaborations; Communication; Communities; Community Networks; Coronavirus; Cost Effectiveness Analysis; County; Data; Death Rate; Development; Effectiveness; Emergency Situation; Emergency response; Evaluation; Evaluation Studies; Event; Expenditure; Facebook; Geography; Goals; Health Promotion; Health Promotion and Education; Health system; Heart failure; Indiana; Individual; Intervention; Interview; Knowledge; Life; Link; Literature; Mediator of activation protein; Modality; Modeling; Multimedia; Naloxone; Naloxone Training; Nature; Opioid; Oral cavity; Outcome; Overdose; Participant; Persons; Phase; Pilot Projects; Population; Prevention; Procedures; Protocols documentation; Public Health; Quasi-experiment; Radio; Randomized; Reaction Time; Reporting; Research; Research Personnel; Sampling; Savings; Science; Services; Small Business Innovation Research Grant; Small Business Technology Transfer Research; Stroke; Surveys; System; Techniques; Technology; Testing; Time; Training; Training Programs; Universities; Urban Community; Washington; Work; arm; base; commune; communication theory; cost; cost effective; cost effectiveness; design; digital; efficacy testing; emergency service responder; evidence base; innovation; innovative technologies; lens; member; opioid epidemic; opioid mortality; opioid overdose; overdose death; posters; randomized controlled study; recruit; response; rural area; skills; social; social cognitive theory; social group; social media; usability; volunteer

This Phase I SBIR will develop and demonstrate the usability/feasibility of the Opioid Rapid Response System (OSSR) in order to reduce deaths and strain on emergency response systems from opioid overdoses. Opioid overdoses exact a tremendous cost in lives and expenditures due to incredible strain on emergency response systems. Naloxone has been developed to counteract overdoses. However, the nature of these events requires a rapid response, a situation that challenges emergency responders in both lightly populated rural areas as well as densely populated urban communities. PulsePoint has developed an app with the potential to obviate both concerns by linking responders to events through the 911 system. PulsePoint is already in place in 4,000 communities throughout the U.S. However, the app cannot accomplish these goals without being used by a large number of citizen responders who are both able to administer life-saving Naloxone and confident in their ability to do so. This project is designed to develop innovative and effective techniques for filling this gap. We build off of the Clark County Pilot Project conducted by members of our team that developed preliminary recruitment and training protocols for enabling citizen responders to utilize the PulsePoint App. Using communication theory, a technology-based recruitment protocol will be built around appeals to individuals (personal identity appeals) and others (communal appeals). Recruitment messages will be disseminated through diverse media channels, including social media, posters, radio announcement, and work-of-mouth. Social Cognitive Theory will be used to develop both online and face-to- face training to enable users to use the PulsePoint App, safely respond to calls, and administer Naloxone. An unblinded, two-arm, parallel group cluster-randomized trial with non-random cluster sampling will be conducted in two Indiana counties to establish the usability and feasibility of ORRS and its recruitment and training components. We anticipate recruiting and training 400 citizen responders. Pretest and posttest surveys will evaluate the training and as well as recruitment exposure through the various channels. County-level data on the number of events to which participant responded as well as lives saved also will be used to evaluate the intervention. A quasi- experimental design will compare the two recruitment strategies and the two training modalities. Project findings will be used to design and more extensive, two statewide evaluation studies (Indiana and Washington) that examine outcomes in numbers of lives saves as well as conducted a cost effectiveness analyses. The project has great promise for rapid and wide dissemination through the PulsePoint network of communities and has the potential to develop a model for community responses to similar public health events (e.g., coronavirus, stroke, heart failure).

I阶段I SBIR将开发并证明阿片类药物的可用性/可行性 快速响应系统（OSSR），以减少死亡并在紧急情况下压力 阿片类药物过量的反应系统。阿片类药物过量服用巨大的成本 由于紧急响应系统的不可思议，生命和支出。 纳洛酮已经开发出来抵消过量药物。但是，这些的本质 事件需要快速响应，这种情况会挑战紧急响应者 两个人口稠密的农村地区以及人口稠密的城市社区。 PulsePoint开发了一个应用程序，有可能通过链接来消除这两种问题 通过911系统对事件的响应者。 Pulsepoint已经有4,000 但是，美国各地的社区无法实现这些目标 不被大量公民响应者使用 管理挽救生命的纳洛酮，并对他们的能力充满信心。这个项目是 旨在开发创新有效的技术来填补这一空白。我们建立了 我们团队成员开发的克拉克县飞行员项目 初步招聘和培训方案，以使公民响应者能够利用 PulsePoint应用程序。使用传播理论，基于技术的招聘 协议将围绕对个人的呼吁（个人身份上诉）和 其他人（公共呼吁）。招聘消息将通过 各种媒体渠道，包括社交媒体，海报，广播公告以及 口腔工作。社会认知理论将用于在线和面对面发展 面对培训以使用户能够使用Pulsepoint应用程序，安全响应呼叫，并 管理纳洛酮。一项无盲，双臂平行的群集群集试验 通过非随机集群抽样将在两个印第安纳州进行 建立ORR及其招聘和培训的可用性和可行性 成分。我们预计招募和培训400名公民响应者。预测试和 测试后调查将评估培训以及通过 各种频道。县级数据，涉及参与者的事件数量 响应以及拯救的生命也将用于评估干预措施。一个准 实验设计将比较两种招聘策略和两个培训 方式。项目发现将用于设计和更广泛的全州两个 评估研究（印第安纳州和华盛顿）检查了 生命节省并进行了成本效益分析。该项目很棒 通过PulsePoint网络的快速和广泛传播的承诺 社区，并有潜力开发一个社区回应的模型 类似的公共卫生事件（例如冠状病毒，中风，心力衰竭）。