Examining the Longitudinal Influence of the Physical and Social Environments on Social Isolation and Cognitive Health: contextualizing the role of technology

检查物理和社会环境对社会孤立和认知健康的纵向影响：将技术的作用置于情境中

• 批准号: 10291360
• 负责人: Kexin Yu
• 金额: $ 4.11万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-15 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10291360
• 关键词: Access to Information; Address; Adopted; Affect; Age; Aging; Alzheimer' s disease related dementia; Attention; Behavior Therapy; Behavioral; Biological Markers; Brain; Cardiovascular Diseases; Characteristics; Clinical Trials; Cognitive; Communication; Communities; Complex; Data; Data Analyses; Development; Disadvantaged; Disease; Effectiveness; Elderly; Enhancement Technology; Environment; Environmental Risk Factor; Equation; Foundations; Goals; Health; Health Status; Home; Impaired cognition; Independent Living; Individual; Internet; Intervention; Intervention Studies; Knowledge; Lead; Life; Literature; Measures; Mediating; Medical Technology; Methods; Modeling; Neighborhoods; Neuropsychology; Outcome; Participant; Pathway interactions; Personality; Phase; Physical environment; Play; Population; Process; Protocols documentation; Publishing; Quality of life; Randomized; Randomized Controlled Trials; Research; Research Activity; Research Personnel; Resources; Risk; Risk Factors; Role; Shapes; Social Change; Social Characteristics; Social Environment; Social Interaction; Social Well-Being; Social isolation; Stimulus; Structure; Technology; Testing; Work; base; behavioral health intervention; cognitive function; cohesion; design; digital; executive function; experience; high risk; improved; intervention program; multilevel analysis; neuroimaging; physical conditioning; pre-doctoral; prevent; protective factors; recruit; satisfaction; social; social engagement; systematic review; theories; tool; trend; β-amyloid burden

PROJECT SUMMARY Social wellbeing and cognitive health are two pillars of successful aging, and they are interrelated. Three decades of research have consistently shown that social isolation is associated with declines in cognitive functioning. Although existing literature has explored the individual-level risk and protective factors, researchers' attention has been less paid to the extent to which physical and social characteristics of the living environment affect social isolation and cognitive health. The Ecological Theory of Aging (ETA) posits environmental factors have significant influences on health and social wellbeing. Negative physical characteristics of the environment were hypothesized to be related to increased social isolation and cognitive decline longitudinally. An increasing amount of research investigated the association between ICT use and social isolation, yet whether ICT use would interact with the effect of environmental factors on the risk of social isolation has not yet been empirically tested. Besides, the influence of ICT use on cognitive health has not been well understood. Promoting social interaction using technology-based approaches have the potential to alleviate social isolation among older people and prevent cognitive decline. The proposed dissertation work (F99) will examine the effect of physical and social environments of living on social isolation and cognitive health. The effects of ICT use will be investigated within living contexts. Multi-level modeling and structural equation modeling methods will be employed to conduct secondary data analysis using data from the National Health & Aging Trend Study (NHATS) wave 5 to 9. The postdoctoral stage (K00) is guided by the overarching aim of building knowledge on the behavioral and contextual pathways that could explain the association between social isolation and cognitive decline and developing a community-based behavioral health intervention. At the K00 phase, the PI will increase understanding of the social isolation and cognitive health research landscape by conducting a systematic review. Longitudinal data from the ongoing Internet-based Conversational Engagement Clinical Trial (I-CONECT) will be analyzed to examine the association between social isolation and change in neuropsychological outcomes. The PI will utilize the longitudinal data collected with the Collaborative Aging Research Using Technology (CART) platform to investigate the relationships between daily activities, social engagement, and the cognitive health of older participants. Knowledge to be built at F99 and K00 stages will be synthesized to inform the participatory co-design of a technology-facilitated intervention program for social isolation and cognitive decline. The proposed research will produce knowledge on the influence of environmental factors on social isolation and cognitive health, and achieve the PI’s long-term professional goal of developing behavioral health intervention to address social isolation and prevent the onset of Alzheimer's Disease and Related Dementias.

项目摘要 社会福祉和认知健康是成功衰老的两个支柱，它们是相互关联的。三 数十年的研究一直表明，社会隔离与认知的下降有关 功能。尽管现有文献探讨了个人级别的风险和保护因素，但研究人员的风险和保护因素 在生活环境的身体和社会特征的程度上，注意力不足以减少 影响社会隔离和认知健康。衰老的生态理论（ETA）的环境因素 对健康和社会福祉产生重大影响。环境的负面身体特征 假设与社会隔离和认知能力下降有关。越来越多 研究数量研究了ICT使用与社会隔离之间的关联，但ICT是否使用 将与环境因素对社会隔离风险的影响相互作用尚未经验 测试。此外，ICT使用对认知健康的影响尚未得到充分理解。促进社会 使用基于技术的方法的互动有可能减轻较老的社会隔离 人并防止认知能力下降。拟议的论文工作（F99）将检查物理的影响 以及社会隔离和认知健康的社会环境。 ICT使用的影响将是 在生活环境中进行了调查。多层建模和结构方程建模方法将是 使用来自国家健康与老化趋势研究（NHATS）的数据进行辅助数据分析 第5至9波。博士后阶段（K00）的指导是建立知识的总体目的 行为和上下文途径，可以解释社会隔离与认知之间的关联 衰落并发展基于社区的行为健康干预措施。在K00阶段，PI将增加 通过进行系统的审查来了解社会隔离和认知健康研究领域。 正在进行的基于Internet的对话参与临床试验（I-Conect）的纵向数据将是 进行了分析，以检查社会隔离与神经心理学结果的变化之间的关联。 PI将利用使用技术（CART）的协作老化研究收集的纵向数据 调查日常活动，社会参与与认知健康之间的关系的平台 年长的参与者。在F99和K00阶段建造的知识将合成以告知参与 针对社会隔离和认知能力下降的技术研究干预计划的共同设计。提议 研究将为环境因素对社会隔离和认知的影响提供知识 健康，并实现PI的长期专业目标，即开发行为健康干预以解决 社会隔离并防止阿尔茨海默氏病和相关痴呆症的发作。

项目成果

Investigating Biological Pathways Underpinning the Longitudinal Association Between Loneliness and Cognitive Impairment.

研究支持孤独感和认知障碍之间纵向关联的生物途径。

• DOI: 10.1093/gerona/glac213
• 发表时间: 2023
• 期刊: The journals of gerontology. Series A, Biological sciences and medical sciences
• 作者: Yu,Kexin;SiangNg,TedKheng
• 通讯作者: SiangNg,TedKheng

Social network and mental health of Chinese immigrants in affordable senior housing during the COVID-19 pandemic: a mixed-methods study.

• DOI: 10.1080/13607863.2023.2213646
• 发表时间: 2023-09
• 期刊: AGING & MENTAL HEALTH
• 影响因子: 3.4
• 作者: Yu, Kexin;Liang, Jiaming;Tung, Yi-Hsuan;Zhang, Mutian;Wu, Shinyi;Chi, Iris
• 通讯作者: Chi, Iris

Vulnerable, Resilient, or Both? A Qualitative Study of Adaptation Resources and Behaviors to Heat Waves and Health Outcomes of Low-Income Residents of Urban Heat Islands.

• DOI: 10.3390/ijerph191711090
• 发表时间: 2022-09-04
• 期刊: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
• 作者: Palinkas, Lawrence A.;Hurlburt, Michael S.;Fernandez, Cecilia;De Leon, Jessenia;Yu, Kexin;Salinas, Erika;Garcia, Erika;Johnston, Jill;Rahman, Md. Mostafijur;Silva, Sam J.;McConnell, Rob S.
• 通讯作者: McConnell, Rob S.