Indiana Diabetes Research Center

印第安纳州糖尿病研究中心

• 批准号: 10286616
• 负责人: Carmella Evans-Molina
• 金额: $ 15.85万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-06 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10286616
• 关键词: Advocate; Animal Experimentation; Animal Model; Animals; Award; Awareness; Basic Science; Bioinformatics; Biological Sciences; Biomedical Engineering; Child; Clinical Research; Collaborations; Communities; Complications of Diabetes Mellitus; Development; Diabetes Mellitus; Diabetic Diet; Diagnosis; Disease; Ecosystem; Endocrine System Diseases; Ensure; Evolution; Extramural Activities; Family suidae; Financial Support; Fostering; Foundations; Funding; Future; Genomics; Goals; Grant; Growth; Human; Indiana; Individual; Influentials; Informatics; Infrastructure; Institution; Knowledge; Learning; Mentors; Mentorship; Metabolic Diseases; Metabolism; Methodological Studies; Microscopy; Mission; Molecular; National Institute of Diabetes and Digestive and Kidney Diseases; Nutritional Study; Obesity; Physiology; Population; Postdoctoral Fellow; Prediabetes syndrome; Proteomics; Research; Research Infrastructure; Research Institute; Research Methodology; Research Personnel; Research Project Grants; Resources; Scientist; Series; Structure; Students; System; Talents; Training; Training Support; Translational Research; Translations; United States National Institutes of Health; Universities; Visit; base; catalyst; collaborative environment; educational atmosphere; human subject; human tissue; innovation; islet; medical schools; member; metabolic abnormality assessment; new growth; next generation; novel; nutrition; programs; ranpirnase; symposium; translational scientist

ABSTRACT (OVERALL CENTER) The mission of the Indiana Diabetes Research Center (IDRC) is to foster knowledge, support training, and promote basic and translational research in diabetes and related metabolic disorders, and their complications. A major focus of the IDRC has been the training and development of the “next generation” of diabetes researcher. This focus has involved a state-wide effort led by the IDRC that has included resource provision (through the Research Cores), financial support and mentoring (through the Pilot and Feasibility Program and institutional funds), and creation of a collaborative diabetes ecosystem (through the Enrichment Program) for a burgeoning pool of investigators at Indiana University School of Medicine and its affiliated research institutions in Indiana (Purdue University, Indiana University-Purdue University in Indianapolis, Indiana University Bloomington, and the Indiana Biosciences Research Institute). The IDRC has been the catalyst for the growth of the Diabetes Research Base by 47% since the funding of this award in 2015. The IDRC consists of a Research Base of 94 highly collaborative investigators who represent 4 research themes: Cellular & Molecular Metabolism; Complications of Diabetes & Obesity; Islet Function & Survival; Nutrition & Physiology of Diabetes and Obesity. Collectively, this group of investigators brings in $46.7M in annual directs from the NIH, of which 50% ($23M) is from NIDDK. The research programs of these investigators is be augmented by 5 state-of-the- art Research Cores (Microscopy, Islet & Physiology, Translation, Swine, and Systems & Informatics Cores). An Enrichment Program, supported by 6 T32 training grants, will enhance learning and discovery. A Pilot and Feasibility Program will grow the Research Base by providing funding to highly promising young investigators. An Administrative Core will oversee governance of the IDRC, and will receive input from an Executive Committee, an Internal Advisory Board, and an External Advisory Board of world-renowned diabetes/metabolism research leaders. The Aims of the IDRC will be to: (1) Promote high impact scientific discoveries by leveraging Research Cores that facilitate collaborations and the use of state-of-the-art methodologies and human studies in diabetes research; (2) Enhance a highly collaborative environment that promotes learning and encourages interaction among investigators; (3) Support the training and innovative research of a burgeoning pool of superb investigators with the potential to become future leaders in diabetes research; (4) Build and strengthen the diabetes research base, support infrastructure to ensure ongoing growth and innovation, and engage with the local community to raise diabetes awareness and involvement.

摘要（整体中心） 印第安纳州糖尿病研究中心（IDRC）的任务是培养知识，支持培训和 促进糖尿病和相关代谢性疾病及其并发症的基本和翻译研究。 IDRC的主要重点是培训和开发糖尿病的“下一代” 研究员。该重点涉及由IDRC领导的全州范围的努力，其中包括资源提供 （通过研究核心），财政支持和心理（通过飞行员和可行性计划以及 机构资金），并创建合作糖尿病生态系统（通过丰富计划） 印第安纳大学医学院及其会员研究机构的调查人员池池 印第安纳州印第安纳大学普渡大学，印第安纳州印第安纳波利斯，印第安纳大学印第安纳大学普渡大学 布卢明顿和印第安纳州生物科学研究所）。 IDRC一直是增长的催化剂 自2015年该奖项的资助以来，糖尿病研究基础的研究基础为47％。 94位高度协作研究人员的研究基础，他们代表4个研究主题：细胞和分子 代谢;糖尿病和肥胖的并发症；胰岛功能和生存；糖尿病的营养和生理 和肥胖。总的来说，这组调查员带来了4670万美元的NIH年度直销活动 50％（2300万美元）来​​自NIDDK。这些研究人员的研究计划被5个最先进的 艺术研究核心（显微镜，胰岛和生理学，翻译，猪以及系统与信息学核心）。 在6 T32培训补助金的支持下，一项丰富计划将增强学习和发现。飞行员和 可行性计划将通过向高度有前途的年轻调查人员提供资金来提高研究基础。 行政核心将监督IDRC的治理，并将收到高管的意见 委员会，内部顾问委员会和世界知名的外部顾问委员会 糖尿病/代谢研究领袖。 IDRC的目的将是： （1）通过利用促进的研究核心来促进高影响科学发现 在糖尿病研究中的合作以及最先进的方法和人类研究的使用； （2）增强高度协作的环境，以促进学习并鼓励互动 在调查人员中； （3）支持对一群精湛的研究人员的培训和创新研究 成为糖尿病研究未来领导者的潜力； （4）建立和加强糖尿病研究基础，支持基础设施以确保持续的增长 和创新，并与当地社区互动以提高糖尿病意识和参与。