MIT Roybal Center for Translational Research to Improve Healthcare for the Aging

麻省理工学院皇家转化研究中心改善老龄化医疗保健

• 批准号: 10281469
• 负责人: Amy N. Finkelstein
• 金额: $ 40.83万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-15 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10281469
• 关键词: Acquired Immunodeficiency Syndrome; Acute pain management; Address; Advance Care Planning; Advance Directives; Affect; Aging; Behavior Therapy; Behavioral Model; Behavioral trial; Caring; Center for Translational Science Activities; Collaborations; Complex; Data; Decision Making; Development; Dose; Elderly; Ensure; Epidemic; Evaluation; Foundations; Funding; Goals; Health; Healthcare; Healthcare Systems; Height; Individual; Institutes; International; Intervention; Lead; Leadership; Massachusetts; Medical; Mission; Modeling; North America; Opioid; Outcome; Overdose; Pain management; Pathway interactions; Patient Preferences; Patients; Peer Review; Personal Satisfaction; Persons; Pilot Projects; Policies; Population; Poverty; Principal Investigator; Process; Program Development; Randomized; Randomized Controlled Trials; Research; Research Project Grants; Resources; Risk; Role; Specialist; Sum; Technology; Testing; Time; United States; Universities; aging population; behavior test; care coordination; community setting; cost; end of life; end of life care; experience; health care delivery; improved; innovation; middle age; novel; opiate tolerance; opioid epidemic; patient tolerability; professor; public health emergency; therapy development; treatment as usual; vehicular accident

ABSTRACT There is no shortage of innovative ideas for behavioral interventions to improve health care delivery in the United States. Health care delivery reform has the potential to dramatically improve the health and health care experience. This is especially true for the aging population who interact with the health care system more frequently and suffer some of the gravest health problems. However, too little is known about which interventions could be effective for improving the health of these individuals. This proposal seeks to identify, fund, and support low-cost, high-impact Stage I trials of behavioral interventions for mid-life and older people. The Abdul Latif Jameel Poverty Action Lab (J-PAL), founded in 2003, is a network of more than 165 affiliated professors at over 55 universities, united by their use of randomized evaluations to answer critical policy questions. J-PAL North America (NA) was launched at the Massachusetts Institute of Technology (MIT) in 2013 by Amy Finkelstein (MIT) and Lawrence Katz (Harvard) to apply the J-PAL approach to the region. J-PAL NA’s Health Care Delivery Initiative (HCDI) focuses on catalyzing high-quality randomized controlled trials (RCTs) to test how best to improve health care delivery. We propose to leverage this foundation to spur and support early-stage RCTs to test behavioral interventions to improve health care delivery and health outcomes for older adults. The MIT Roybal Center will support two Stage I pilots in its first year, and will select additional pilot projects in Years 2-5 through a rigorous peer review process. Our proposed Year 1 projects are: Project 1: Deferring Agency at End-of-Life: The Role of Information and Advance Directives. This project focuses on policies related to medical care and decision-making at end-of-life, a topic that is broadly relevant to the aging population. Project 2: Post-Acute Pain Management for Opioid-Tolerant Patients: A Randomized Controlled Trial. This project seeks to provide rigorous evidence on how to effectively manage pain in patients who are already on high doses of opioids and thus at risk of a host of negative outcomes, including overdose. Each of these projects will be supported by (i) the Management and Administrative Core, which will provide overall leadership and coordination for the Center and (ii) the Pilot Core. The Pilot Core will support project development activities to identify promising Stage I research projects, coordinate selection of the most promising pilots for funding, support funded pilots, and create a sustained behavioral intervention development program to improve health outcomes for older adults.

抽象的 在改善医疗保健服务方面，不乏行为干预的创新理念。 美国。医疗保健服务改革有可能显着改善健康和医疗保健。 对于与医疗保健系统互动更多的老龄化人口来说尤其如此。 经常出现并遭受一些最严重的健康问题，但是，人们对其中哪些问题知之甚少。 该提案旨在确定，干预措施可以有效改善这些人的健康。 资助并支持针对中年和老年人的低成本、高影响力的行为干预第一阶段试验。 安利捷贫困行动实验室 (J-PAL) 成立于 2003 年，是一个由超过 165 家附属机构组成的网络 超过 55 所大学的教授通过随机评估来回答关键政策 J-PAL 北美 (NA) 在麻省理工学院 (MIT) 推出。 2013 年，艾米·芬克尔斯坦（麻省理工学院）和劳伦斯·卡茨（哈佛大学）将 J-PAL 方法应用于该地区。 NA 的医疗保健服务计划 (HCDI) 专注于促进高质量的随机对照试验 （随机对照试验）来测试如何最好地改善医疗保健服务。我们建议利用这一基础来刺激和改善医疗保健服务。 支持早期随机对照试验来测试行为干预措施，以改善医疗保健服务和健康结果 麻省理工学院皇家中心将在第一年支持两名第一阶段试点项目，并将选择更多的项目。 通过严格的同行评审流程在第 2-5 年开展试点项目 我们提议的第 1 年项目是： 项目 1：临终时的延期代理：信息和预先指示的作用该项目。 重点关注与临终医疗保健和决策相关的政策，该主题与以下领域广泛相关 人口老龄化。 项目 2：阿片类药物耐受患者的急性后疼痛管理：随机对照试验。 该项目旨在为如何有效管理已经接受治疗的患者的疼痛提供严格的证据 高剂量的阿片类药物，因此面临一系列负面后果的风险，包括过量服用。 这些项目中的每一个都将得到 (i) 管理和行政核心的支持，该核心将提供 该中心和 (ii) 试点核心的全面领导和协调 试点核心将支持项目。 开发活动，以确定有前途的第一阶段研究项目，协调选择最有前途的研究项目 资助试点，支持资助试点，并创建持续的行为干预发展 改善老年人健康状况的计划。