Temporal dyadic processes in autism risk and treatment

自闭症风险和治疗的时间二元过程

基本信息

批准号：
10227945
负责人：
Ashleigh Kellerman
金额：
$ 4.6万
依托单位：
PURDUE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-01 至 2022-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10227945
关键词：
2 year old 4 year old 5 year old Address Advocate Age Behavior Behavioral Child Childhood Classification Code Cognition Competence Dancing Data Data Set Development Diagnosis Distress Early Intervention Elements Evidence based intervention Eye Family Family history of Frequencies Goals Growth Health Services Accessibility Heritability Heterogeneity Home visitation Indiana Infant Intervention Language Life Measurement Mediating Methodology Methods Modeling Monitor Mother-Child Relations Mothers Outcome Parent-Child Relations Parents Pattern Play Process Psychopathology Recommendation Research Research Personnel Risk Sampling Services Social Behavior Social Change Social Development Social Interaction Social Processes Specificity Symptoms Techniques Testing Time Training United States autism spectrum disorder base clinically relevant disorder risk dyadic interaction early childhood experience flexibility high risk high risk infant improved indexing innovation joint attention post intervention prospective rate of change repetitive behavior service intervention social social communication social deficits social skills statistics therapy design time use

项目摘要

PROJECT SUMMARY/ABSTRACT Autism spectrum disorder (ASD) is currently one of the most heritable, heterogeneous, and prevalent childhood psychopathologies and is characterized by social communicative difficulties, as well as restricted, repetitive behaviors. However, many of these communicative and behavioral difficulties may not fully manifest until later in development. My long-term goal is to improve children’s developmental trajectories by identifying early social difficulties within the first two years to better inform behavioral targets within ongoing intervention efforts (e.g., responsiveness; joint attention). Copious research highlights that difficulties in early social exchanges inform later developmental difficulties in language, cognition, and more advanced social communication exchanges. However, the behavioral methods we currently use to assess mean-level social difficulties (e.g., average vocal exchanges) in young children are often limited by inconsistent findings, sample constraints, and large heterogeneity across children/families. This measurement limitation inevitably complicates our interpretations of which social behaviors are (1) indicative of later ASD diagnosis, and (2) which behaviors should be the focus of intervention efforts. Until recently, available methods to accurately and precisely describe dyadic interactions have been limited- and it is widely recognized that dyadic interactions are not fully captured by mean-level statistics (e.g., total frequency of eye contact). Thus, the overall objective of the proposed study is to apply two distinct temporal-based dyadic methodologies (i.e., state space grids; time varying effect modeling) to existing dyadic data in order to sequentially capture the unfolding temporal pattern present within parent-child interactions in elevated-risk samples. The central goal of this study is to improve current measurement recommendations by providing sequential-based representations of early social exchanges during play, in both developmental monitoring (Aim 1) and parent-mediated intervention (Aim 2) contexts. The proposed study is innovative in its application of two temporal-based dyadic methodologies that have never been applied in elevated-risk samples. At its core, ASD is a social disorder and improving our understanding of how these social difficulties unfold over the first two years of life has the potential to significantly impact our current field recommendations for optimizing children’s social development within ongoing identification and intervention contexts.

项目摘要/摘要自闭症谱系障碍（ASD）目前是最遗传，异质和普遍的一种儿童精神病理学，其特征是社会沟通困难以及受限制的特征重复行为。但是，这些交流和行为困难中的许多可能无法完全体现直到开发。我的长期目标是通过识别来改善儿童的发育轨迹最初两年内的早期社会困难，以更好地告知行为目标。努力（例如，响应能力；联合注意）。丰富的研究强调了早期社会的困难交易所为以后的语言，认知和更先进的社交方面的发展困难提供了信息沟通交流。但是，我们目前用来评估平均水平社会的行为方法幼儿的难度（例如，平均声音交流）通常受到不一致的发现的限制，样本儿童/家庭之间的约束和巨大的异质性。这种测量限制不可避免地使我们对哪些社会行为是（1）表示后来ASD诊断的解释变得复杂，（2）哪些行为应该是干预工作的重点。直到最近，可用的方法准确和精确地描述了二元相互作用是有限的 - 广泛认识到二元相互作用未通过平均值统计数据完全捕获（例如，目光接触的总频率）。那，总体目标拟议的研究是应用两种不同的基于临时的二元方法（即状态空间网格；时间变化的效果建模）与现有的二元数据，以便依次捕获展开的临时性在高高的风险样本中，亲子相互作用中存在模式。这项研究的核心目标是通过提供早期社会的基于顺序的表示，改善当前的测量建议游戏期间的交流，在发展监测（AIM 1）和父介导的干预措施（AIM 2）上下文。拟议的研究在应用两种基于临时的二元方法方面具有创新性从未应用于高高的风险样品。从本质上讲，ASD是一种社会障碍，并改善了我们的了解这些社会困难在生命的头两年中如何发展有潜力显着影响我们目前的现场建议，以优化儿童的社会发展持续的识别和干预环境。

项目成果

期刊论文数量（3）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Are Maternal Self-Reports of Social Difficulties Apparent in Interactions with their Children?

母亲对社交困难的自我报告在与孩子的互动中是否明显？

DOI：
10.1007/s10803-022-05786-7
发表时间：
2022
期刊：
Journal of autism and developmental disorders
影响因子：
3.9
作者：
Kellerman,AM;Masters,C;Schwichtenberg,AJ
通讯作者：
Schwichtenberg,AJ

Dyadic Synchrony and Responsiveness in the First Year: Associations with Autism Risk.

DOI：
10.1002/aur.2373
发表时间：
2020-12
期刊：
Autism research : official journal of the International Society for Autism Research
影响因子：
0
作者：
Kellerman AM;Schwichtenberg AJ;Abu-Zhaya R;Miller M;Young GS;Ozonoff S
通讯作者：
Ozonoff S

Dyadic interactions in children exhibiting the broader autism phenotype: Is the broader autism phenotype distinguishable from typical development?