Decreasing the Engagement Gap for Addiction Treatment in Primary Care

缩小初级保健中成瘾治疗的参与差距

基本信息

批准号：
10222485
负责人：
Joseph Edwin Glass
金额：
$ 18.1万
依托单位：
KAISER FOUNDATION RESEARCH INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-08-01 至 2022-09-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10222485
关键词：
Address Adult Advisory Committees Alcohols Anxiety Caring Cellular Phone Cessation of life Communities Complex Computer software Data Collection Data Set Development Development Plans Effectiveness Ensure Environment Evidence based treatment FDA approved Funding Future Glass Goals Health Health Services Research Individual Institution Intervention Intervention Trial Interview K-Series Research Career Programs Knowledge Lead Life Medical Mental Depression Mental disorders Mentors Mentorship Meta-Analysis Monitor Motivation Outcome Pacific Northwest Patient Care Patient-Focused Outcomes Patients Preventive service Primary Health Care Protocols documentation Provider Psychological reinforcement Public Health Randomized Controlled Trials Readiness Rehabilitation therapy Research Research Institute Research Personnel Research Support Sampling Severities Social Workers Substance Use Disorder Support System System Testing Therapeutic Time Tobacco use Training Treatment Cost Treatment outcome United States National Institutes of Health Visit acceptability and feasibility addiction alcohol abuse therapy alcohol measurement alcohol screening and brief intervention alcohol use disorder base brief intervention care systems career development comorbid depression comorbidity cost cost effective craving design effective therapy effectiveness trial evidence base experience improved improved outcome innovation mHealth medical specialties novel novel strategies online intervention pragmatic trial programs prototype public health relevance sociodemographic group substance use tool trial design web site

项目摘要

Project Summary Significance. Alcohol use disorders (AUDs) are common, costly, and life-threatening, but just 8 in 100 people with a past-year AUD receive treatment. Most individuals with AUDs visit primary care and prefer to receive AUD treatment in primary care. This represents a missed opportunity. Career Development Plan. Dr. Glass is a clinician researcher who has successfully answered important research questions by analyzing complex secondary datasets. His long-term goal is to conduct intervention trials in primary care in order to increase the reach and impact of addiction treatment. The proposed K01 career development award will ensure that he receives the mentoring, training, and research experience needed to achieve this goal. Because new mobile health (mHealth) programs offer a relatively novel—and potentially cost-effective and scalable—approach to increasing the reach of effective AUD treatments into primary care, Dr. Glass will focus his training on data collection and preparing for an effectiveness trial of a promising mHealth intervention for patients with AUDs. This will prepare him to lead rigorous, state-of-the-art trials of AUD interventions in primary care, and ensure he reaches his potential as a leader in AUD research. Research Plan. Dr. Glass's proposed research will evaluate the feasibility and acceptability of an existing mHealth tool (Square2) as a new option for managing AUDs in primary care. The Square2 program includes several evidence-based electronic tools for addiction treatment and associated comorbidity (depression, anxiety and tobacco use), and is designed to address the needs of primary care patients irrespective of their AUD severity or readiness to change. However, Square2 has not yet been empirically tested in primary care or for AUD treatment, and developmental research is needed to identify the optimal approach to engaging a generalizable primary care sample of patients with AUDs in a trial of Square2. Specific aims for the proposed K01 are: (Aim 1) Assess the needs of primary care patients with AUDs, and clinicians who care for them, for use of mHealth as part of primary care management of AUDs (n = 40); and (Aim 2) Pilot a randomized controlled trial (RCT) to inform a future effectiveness trial by assessing a) the feasibility and acceptability of delivering Square2 in primary care with clinician assistance, and b) the feasibility of the RCT design (n = 60). Mentorship and Environment. Expert investigators in AUDs in primary care (Primary Mentor Dr. Bradley); mHealth (Co-Mentors Drs. Marsch and McClure); data collection (Co-Mentor Dr. Curran); and pragmatic trials (advisor Dr. Simon) will support this research. The research will be conducted at the Group Health Research Institute, an innovative research institution embedded in a large primary care system in the Pacific Northwest. Public Health Impact: The proposed activities will ensure the development of Dr. Glass into an innovative independent researcher. Moreover, the proposed research will lay the groundwork for future R01s of mHealth tools to increase the reach of effective AUD treatments, thereby improving outcomes for patients with AUDs.

项目摘要意义。酒精使用障碍（AUD）很常见，昂贵且威胁生命，但在100中只有8个过去一年AUD的人接受治疗。大多数有音频的人都会访问初级保健，并且更喜欢在初级保健中接受AUD治疗。这代表了错过的机会。职业发展计划。格拉斯博士是一位临床研究人员，他成功回答了重要通过分析复杂的辅助数据集进行研究问题。他的长期目标是进行干预在初级保健中的试验，以增加成瘾治疗的覆盖范围和影响。拟议的K01 职业发展奖将确保他获得心理，培训和研究经验需要实现这一目标。因为新的移动健康（MHealth）计划提供了相对小说，并且潜在的具有成本效益和可扩展性的可能性 - 将有效的AUD处理范围提高到初级保健，格拉斯博士将把他的培训集中在数据收集上，并为一项有效试验做准备有希望的MHealth干预AUD患者。这将使他领导严格，最先进的对初级保健的AUD干预措施的试验，并确保他在AUD研究领域发挥了自己的潜力。研究计划。格拉斯博士的拟议研究将评估现有的可行性和可接受性 MHealth工具（Square2）是管理初级保健AUDS的新选择。 Square2程序包括几种基于证据的电子工具用于成瘾治疗和相关合并症（抑郁症，动画和烟草使用），旨在满足初级保健患者的需求听觉严重性或准备改变。但是，Square2尚未在初级保健或对于AUD治疗，需要开发研究来确定参与的最佳方法在Square2试验中，AUD患者的可推广初级保健样本。提议的具体目标 K01是：（ AIM 1）评估AUDS的初级保健患者的需求，以及关心它们的临床医生使用MHealth作为AUDS初级保健管理的一部分（n = 40）；（目标2）驾驶随机的对照试验（RCT）通过评估A）在临床援助的情况下提供基础护理方面的Square2，b）RCT设计的可行性（n = 60）。指导和环境。初级保健AUDS的专家调查员（主要导师Bradley博士）； MHealth（Marsch和McClure博士）；数据收集（Co-Incertor Curran博士）；和务实的试验（顾问西蒙博士）将支持这项研究。该研究将在小组健康研究中进行 Institute是一家创新的研究机构，该机构嵌入了太平洋西北部的大型初级保健系统中。公共卫生影响：拟议的活动将确保Glass博士发展为创新独立研究员。此外，拟议的研究将为MHealth的未来R01奠定基础增加有效的AUD治疗范围的工具，从而改善了AUD患者的结果。

项目成果

期刊论文数量（6）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Receipt of evidence-based alcohol-related care in a national sample of transgender patients with unhealthy alcohol use: Overall and relative to non-transgender patients.

DOI：
10.1016/j.jsat.2021.108565
发表时间：
2021-12
期刊：
Journal of substance abuse treatment
影响因子：
3.9
作者：
Williams EC;Chen JA;Frost MC;Rubinsky AD;Edmonds AT;Glass JE;Lehavot K;Matson TE;Wheat CL;Coggeshall S;Blosnich JR
通讯作者：
Blosnich JR

Study protocol for a factorial-randomized controlled trial evaluating the implementation, costs, effectiveness, and sustainment of digital therapeutics for substance use disorder in primary care (DIGITS Trial).

DOI：
10.1186/s13012-022-01258-9
发表时间：
2023-02-01
期刊：
IMPLEMENTATION SCIENCE
影响因子：
7.2
作者：
Glass, Joseph E.;Dorsey, Caitlin N.;Beatty, Tara;Bobb, Jennifer F.;Wong, Edwin S.;Palazzo, Lorella;King, Deborah;Mogk, Jessica;Stefanik-Guizlo, Kelsey;Idu, Abisola;Key, Dustin;Fortney, John C.;Thomas, Rosemarie;McWethy, Angela Garza;Caldeiro, Ryan M.;Bradley, Katharine A.
通讯作者：
Bradley, Katharine A.

Implementation and workflow strategies for integrating digital therapeutics for alcohol use disorders into primary care: a qualitative study.

DOI：
10.1186/s13722-023-00387-w
发表时间：
2023-05-08
期刊：
ADDICTION SCIENCE & CLINICAL PRACTICE
影响因子：
3.7
作者：
Mogk, Jessica M. M.;Matson, Theresa E. E.;Caldeiro, Ryan M. M.;Mcwethy, Angela M. Garza M.;Beatty, Tara;Sevey, Brandie C. C.;Hsu, Clarissa W. W.;Glass, Joseph E. E.
通讯作者：
Glass, Joseph E. E.

Disparities in Documented Drug Use Disorders Between Transgender and Cisgender U.S. Veterans Health Administration Patients.