Juno

朱诺

• 批准号: 10042790
• 金额: $ 6.37万
• 依托单位: LUGOS TECHNOLOGY LTD
• 依托单位国家: 英国
• 项目类别: Grant for R&D
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10042790
• 关键词: Juno

The impact of wounds is significant: costing the NHS ~£5,600,000,000 p.a. and responsible for ~37,000 deaths, with infections leading to permanent disability and decreased quality of life. The conflated cost of wound treatment ranges from £5,000-£11,200 per patient/year.Lugos are developing a system to instantly & accurately diagnose infections and identify specific pathogens in open wounds using optical, light-based technologies. Following pathogen identification, the system will deliver treatment to eradicate pathogens in the wound and instantly confirm that the treatment has proved effective. The system incorporates an easy-to-use mobile phone app & low-cost device for evaluation of open-wounds by the patient/carer at home, to enable continuous daily self-monitoring of the healing of open wounds throughout treatment & instantly highlighting when clinical intervention is required, well before any infection becomes chronic.The impact of successful implementation will remove diagnostic variability, improved patient outcomes & lead to reduced antibiotic reliance. The system will take up to two years to develop & undergo testing & clinical trials.Initial discussions with potential investors and customers has raised significant interest in the unique approach; however, in order to attract private investor funding at this early stage we have recognised that a demonstrator of the system and the holistic approach would support our communication activities.The key objective of _**Juno**_ is to develop a demonstrator & basic, working infrastructure to be able to gain buy-in/support from potential investors/users & to provide valuable feedback to full system development. Juno will employ existing technologies to simulate how the fully developed system would be used in operationThe _**Juno**_ project will focus on developing a fully functional demonstrator, using the funding to develop an operational system using printed images of wounds instead of in-vitro samples (some images containing hidden printed signatures to simulate infection & some images demonstrating a progressive series of healing wounds). We will develop a demonstrator mobile app, and remote online-database,utilising the phone's camera to capture images in real-time and referring to the database to instantly identify differences between infected,non-infected and progressively healing wounds. Illustrating how the fully developed system would operate in use. We will use this demonstrator system to prepare literature, images & video demonstrations to show how simply the fully developed system will work & use this demonstrator in-person to gain buy-in from investors & feedback from potential customers/users.

伤口的影响是巨大的：每年给 NHS 造成约 5,600,000,000 英镑的损失，导致约 37,000 人死亡，感染会导致永久性残疾并降低生活质量，每位患者每年的伤口治疗费用为 5,000 英镑至 11,200 英镑。 Lugos 正在开发一种系统，可在病原体识别后使用光学、光技术立即准确地诊断感染并识别开放性伤口中的特定病原体。该系统将提供治疗以根除伤口中的病原体，并立即确认治疗已被证明有效。该系统包含易于使用的手机应用程序和低成本设备，用于患者/护理人员评估开放性伤口。在家中，能够在整个治疗过程中每天连续自我监测开放性伤口的愈合情况，并在任何感染成为慢性感染之前立即突出显示何时需要临床干预。成功实施的影响将消除诊断变异性，改善患者结果并导致减少该系统最多需要两个抗生素依赖。开发和进行测试和临床试验的时间。与潜在投资者和客户的初步讨论引起了人们对这种独特方法的极大兴趣，但是，为了在早期阶段吸引私人投资者资金，我们已经认识到该系统的演示者和整体方法将支持我们的沟通活动。_**Juno**_ 的主要目标是开发一个演示器和基本的工作基础设施，以便能够获得潜在投资者/用户的认可/支持，并提供有价值的反馈朱诺号将采用完整的系统开发。现有技术来模拟完全开发的系统如何在操作中使用朱诺项目将重点开发功能齐全的演示器，利用这笔资金开发一个使用伤口打印图像而不是体外样本的操作系统（一些图像包含隐藏的印刷签名以模拟感染，一些图像展示了一系列渐进的愈合伤口）我们将开发一个演示移动应用程序和远程在线数据库，利用手机的摄像头实时捕获图像并参考数据库可以立即识别之间的差异说明完全开发的系统在使用中如何运行我们将使用该演示系统准备文献、图像和视频演示，以展示完全开发的系统如何简单地工作并使用该演示系统。 -获得投资者支持和潜在客户/用户反馈的人。