Juno

朱诺

• 批准号: 10042790
• 金额: $ 6.37万
• 依托单位: LUGOS TECHNOLOGY LTD
• 依托单位国家: 英国
• 项目类别: Grant for R&D
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10042790
• 关键词: Juno; Juno

The impact of wounds is significant: costing the NHS ~£5,600,000,000 p.a. and responsible for ~37,000 deaths, with infections leading to permanent disability and decreased quality of life. The conflated cost of wound treatment ranges from £5,000-£11,200 per patient/year.Lugos are developing a system to instantly & accurately diagnose infections and identify specific pathogens in open wounds using optical, light-based technologies. Following pathogen identification, the system will deliver treatment to eradicate pathogens in the wound and instantly confirm that the treatment has proved effective. The system incorporates an easy-to-use mobile phone app & low-cost device for evaluation of open-wounds by the patient/carer at home, to enable continuous daily self-monitoring of the healing of open wounds throughout treatment & instantly highlighting when clinical intervention is required, well before any infection becomes chronic.The impact of successful implementation will remove diagnostic variability, improved patient outcomes & lead to reduced antibiotic reliance. The system will take up to two years to develop & undergo testing & clinical trials.Initial discussions with potential investors and customers has raised significant interest in the unique approach; however, in order to attract private investor funding at this early stage we have recognised that a demonstrator of the system and the holistic approach would support our communication activities.The key objective of _**Juno**_ is to develop a demonstrator & basic, working infrastructure to be able to gain buy-in/support from potential investors/users & to provide valuable feedback to full system development. Juno will employ existing technologies to simulate how the fully developed system would be used in operationThe _**Juno**_ project will focus on developing a fully functional demonstrator, using the funding to develop an operational system using printed images of wounds instead of in-vitro samples (some images containing hidden printed signatures to simulate infection & some images demonstrating a progressive series of healing wounds). We will develop a demonstrator mobile app, and remote online-database,utilising the phone's camera to capture images in real-time and referring to the database to instantly identify differences between infected,non-infected and progressively healing wounds. Illustrating how the fully developed system would operate in use. We will use this demonstrator system to prepare literature, images & video demonstrations to show how simply the fully developed system will work & use this demonstrator in-person to gain buy-in from investors & feedback from potential customers/users.

奖金的影响很大：耗资NHS约5,60万英镑。并导致约37,000人死亡，感染导致永久性残疾和改善生活质量。伤口治疗的混合成本范围从每位患者/年为5,000英镑至11,200英镑。Lugos正在开发一种系统，以立即准确地诊断感染并使用基于光的基于光的，基于光的技术来识别开放性伤口的特定病原体。在病原体鉴定后，该系统将在获胜中为放射疗法病原体提供治疗，并立即证实该治疗已被证明有效。该系统结合了一种易于使用的手机应用程序和低成本设备，用于评估患者/护理人员在家中的开放障碍，以使整个治疗中的开放伤口的愈合持续进行每天的自我监测，并在需要临床干预时立即强调，在任何感染都需要临床干预时。该系统将需要长达两年的时间来开发和进行测试和临床试验。与潜在的投资者和客户进行的重要讨论引起了人们对独特方法的重大兴趣。但是，为了在早期阶段吸引私人投资者资金，我们已经认识到，该系统和整体方法的演示者将支持我们的沟通活动。 Juno将采用现有技术来模拟操作中如何使用全面开发的系统。我们将开发一个示威者移动应用程序和远程在线数据库，利用手机的相机实时捕获图像，并参考数据库，以立即确定受感染，未感染和逐步康复增长之间的差异。插图完全开发的系统将如何使用。我们将使用此演示器系统来准备文献，图像和视频演示，以展示完全开发的系统将如何工作并使用该演示者亲自使用该演示者，从而从潜在客户/用户的投资者和反馈中获得买入。