Rapid Response and Pilot Research Core

快速反应和试点研究核心

基本信息

批准号：
10219224
负责人：
REBEKAH K HERSCH
金额：
$ 30.68万
依托单位：
GEORGE MASON UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-06-15 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10219224
关键词：
Address Adopted Adverse event Advisory Committees Affect Annual Reports Applications Grants Area Collaborations Communities Data Collection Direct Costs Ensure Event Faculty Family Feedback Funding Funding Opportunities Goals Grant Health Individual Infrastructure Intervention Justice Knowledge Lead Leadership Learning Mentors Mentorship Methodology Methods Monitor National Institute of Drug Abuse Opioid Participant Performance Pilot Projects Policies Population Prevention Procedures Process Progress Reports Publications Reporting Research Research Personnel Research Project Grants Resources Senior Scientist Source Testing Time Translations Universities Work advanced analytics career cost dissemination strategy education research experience innovation interest member novel opioid use disorder prevent programs research and development research study response skills tool web site

项目摘要

The Rapid Response and Pilot Research (RRPR) Core of the Mason Coordination and Translation Center (MCTC) will develop and maintain an effective process that facilitates research of emerging policies and practices related to the opioid use disorder (OUD) among justice-involved individuals, their families, or communities. The RRPR Core has four specific aims: 1) establish an Advisory committee, including those within and outside of JCOIN; 2) develop the infrastructure, policies, and procedures for a rapid cycle pilot research application and grant funding program; 3) monitor funded programs through regular monthly and annual reporting; and 4) create a process that encourages novel research projects. The RRPR Core, led by Dr. Rebekah Hersch, Associate Director for Research Development at George Mason University (Mason), will work alongside NIDA, the Steering Committee (SC), the Administration (Admin), the Dissemination and Stakeholder Engagement (D/SE), and the Research Education (Learning Experiences to Advance Practice [LEAP]) Cores to adopt, adapt, and implement an application submission procedure. Dr. Hersch has extensive experience overseeing funding opportunities, and Mason has the infrastructure to support such initiatives. The RRPR Advisory Committee will consist of NIDA staff, JCOIN organizations, and an External Advisory Panel, including representatives of families or individuals affected by OUD. To identify innovative studies, including time-sensitive ideas and concepts that can be rapidly funded and tested, calls for proposals will occur three times per year. The RRPR Core will work with the Admin and D/SE Cores to publicize the funding announcements and reach broad audiences to promote novel study ideas. Small innovative studies will be encouraged, using various methodologies, to address OUD. Applicants will be required to identify a JCOIN investigator to work with, including teaming with a Methodology and Advanced Analytics Resource Center methodologist. If an applicant is not affiliated with JCOIN, the RRPR Core will assist them in connecting with an investigator interested in their project. This is intended to encourage promising research from outside the JCOIN community. All applications will be reviewed by three individuals from the Advisory Committee, who will provide written feedback along with a numerical score; recommended projects will be submitted to SC and NIDA for input and approval. Funded projects will be limited to a 24-month project period and $100,000 of direct cost funding. The review process will be rapid cycle ensuring that pilot funds of $350,000 are allocated each year. Progress reports summarizing milestones, deliverables, performance metrics, and responses to adverse events will be required monthly. The RRPR Core will work with funded projects that encounter challenges by providing a senior scientist to help correct course. Funded projects will be required to submit a final report within three months after project completion; the results of these studies will be available online for the public. The RRPR Core will be essential to infusing NIDA and JCOIN with novel research ideas, piloting new ideas, and building the research evidence around OUD.

梅森协调与翻译中心的快速响应和试点研究 (RRPR) 核心（MCTC）将开发和维护一个有效的流程，以促进对新兴政策和涉及正义的个人、其家人或与阿片类药物使用障碍 (OUD) 相关的做法社区。 RRPR 核心有四个具体目标： 1) 建立一个咨询委员会，其中包括以及 JCOIN 之外； 2) 制定快速循环试点研究的基础设施、政策和程序申请和拨款资助计划； 3) 通过定期的月度和年度监测资助项目报告； 4) 创建一个鼓励新颖研究项目的流程。 RRPR 核心，由 Rebekah 博士领导乔治梅森大学 (Mason) 研究开发副主任 Hersch 将与 NIDA、指导委员会 (SC)、行政部门 (Admin)、传播和利益相关者参与（D/SE）和研究教育（促进实践的学习经验[LEAP]）核心采用、调整和实施申请提交程序。 Hersch博士拥有丰富的经验监督融资机会，梅森拥有支持此类举措的基础设施。 RRPR 咨询委员会将由 NIDA 工作人员、JCOIN 组织和外部咨询小组组成，其中包括受 OUD 影响的家庭或个人的代表。确定创新研究，包括时间敏感的研究对于可以快速资助和测试的想法和概念，每年将进行三次提案征集。 RRPR 核心将与管理和 D/SE 核心合作，公布资助公告并达成共识广大受众推广新颖的学习理念。将鼓励小型创新研究，利用各种方法论，解决 OUD。申请人需要指定一名 JCOIN 调查员与之合作，包括与方法论和高级分析资源中心方法学家合作。如果申请人不隶属于 JCOIN，RRPR 核心将协助他们联系对其感兴趣的调查员项目。此举旨在鼓励 JCOIN 社区之外的有前景的研究。所有应用程序将由咨询委员会的三名人员进行审查，他们将提供书面反馈以及数字分数；推荐项目将提交给SC和NIDA供输入和批准。资助项目将仅限于 24 个月的项目期和 100,000 美元的直接成本资金。审查过程将周期短，确保每年分配 35 万美元的试点资金。进度报告总结每月需要提供里程碑、可交付成果、绩效指标以及对不良事件的响应。这 RRPR Core 将与遇到挑战的受资助项目合作，提供资深科学家帮助纠正课程。资助项目须在项目完成后三个月内提交最终报告；这这些研究的结果将在网上向公众公布。 RRPR 核心对于注入 NIDA 至关重要和 JCOIN 具有新颖的研究思路，试点新想法，并围绕 OUD 建立研究证据。