Efficacy of a Healthy Lifestyle Intervention to Prevent Depression in Older Spousally-bereaved Adults-Supplement

健康生活方式干预对预防老年丧偶者抑郁症的功效-补充

• 批准号: 10217532
• 负责人: Sarah T Stahl
• 金额: $ 18万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-23 至 2022-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10217532
• 关键词: Adherence; Administrative Supplement; Adult; Advertising; Age; Anxiety; Bereavement; COVID-19; COVID-19 pandemic; Cause of Death; Cessation of life; Characteristics; Collaborations; Communities; Data; Disease; Elderly; Feeling; Feeling suicidal; Funding; Geographic Locations; Grief reaction; Hamilton Rating Scale for Depression; Health; Individual; Intervention; Longitudinal Studies; Major Depressive Disorder; Measurement; Measures; Mental Depression; Mental Health; Mental disorders; Monitor; Mourning; Patient Recruitments; Prevention; Process; Public Health; Readiness; Research; Resources; Rest; Ritual compulsion; Science; Self Management; Services; Shock; Sleep; Social Distance; Social isolation; Social support; Spouses; Sum; Symptoms; Technology; Time; Treatment outcome; Universities; Widow; Widower; base; behavior change; behavior influence; behavioral health; behavioral health intervention; burden of illness; circadian; depression prevention; depressive symptoms; digital; experience; follow-up; healthy lifestyle; high risk; improved; lifestyle intervention; loved ones; pandemic disease; post-traumatic stress; prevent; psychiatric symptom; psychologic; theories; uptake; wearable device

PROJECT SUMMARY/ABSTRACT Older spousally-bereaved adults are at very high risk for major depressive disorder (MDD). In the age of COVID-19, the inability to engage in rituals that support the grieving process will make it much more difficult to cope with the death of a spouse. This proposed Administrative Supplement leverages our funded R01 “Efficacy of a Healthy Lifestyle Intervention to Prevent Depression in Older Spousally-bereaved Adults” (WELL) to increase the reach, uptake, and sustainability of our existing behavioral-health intervention to accommodate older spouses bereaved by COVID-19 who are seeking prevention and self-management strategies to manage psychiatric symptoms both during and following the pandemic. We will use digital advertising to optimize reach and access in geographic locations heavily impacted by the COVID-19 pandemic. To promote adherence to and sustained use of WELL, we will use existing data (K01 MH103467) to identify individual and intervention- level characteristics that are associated with discontinuation vs sustained use of digital interventions for mental health support. Additional measurements of death, dying, and bereavement (preparedness for death, lack of closure, social isolation, and loss of mourning rituals) will be obtained for the 100 participants recruited over the Supplement’s two-year time frame. The data will be used to examine both the impact of COVID-19 death on depression symptoms (collected through this supplement) and trajectories of depression symptoms over one year (collected through this supplement during the WELL follow-up time period). The aims of the proposed research will examine in older spousally-bereaved adults at high risk for MDD (due to subthreshold symptoms of depression) (1) whether depression symptom burden is higher in older spouses bereaved by COVID-19 than those bereaved by other causes of death; and (2) whether COVID-19 bereavement is associated with other psychopathological conditions including anxiety, post-traumatic stress, suicidal ideation, and prolonged grief disorder(s). In sum, WELL provides a unique opportunity to examine the relationship between COVID-19 death and surviving spouses’ psychiatric symptoms in a large longitudinal study of community-dwelling older spouses particularly vulnerable to MDD due to spousal bereavement.

项目摘要/摘要 年长的间谍菌属成年人患严重抑郁症（MDD）的风险很高。在年龄 COVID-19，无法参与支持悲伤过程的仪式将使更难 应对配偶的死亡。该提议的行政补充利用了我们资助的R01“功效 健康的生活方式干预措施，以防止年龄较老的成年人的抑郁症”（井） 提高现有行为健康干预措施的影响力，吸收和可持续性 Covid-19丧亲的年长配偶，他们正在寻求预防和自我管理策略来管理 大流行期间和之后的精神病符号。我们将使用数字广告来优化覆盖范围 并在地理位置的通道受到了19日大流行的严重影响。促进遵守 并持续使用井，我们将使用现有数据（K01 MH103467）来识别个人和干预 - 与停用与持续使用数字干预措施相关的水平特征 健康支持。死亡，垂死和丧亲的其他测量（准备死亡，缺乏 将为100名参与者获得封闭，社会隔离和丧失哀悼仪式的仪式） 补充的两年时间范围。数据将用于检查Covid-19死亡对 抑郁症状（通过这种补充剂收集）和抑郁症状的轨迹 年（通过此补品在井的随访时间期间收集）。提议的目的 研究将检查具有MDD高风险的老年间隔的成年人（由于亚阈值症状 抑郁症）（1）抑郁症状伯恩伯伯恩（Covid-19）丧亲的老年配偶比 那些因其他死亡原因而死的人； （2）COVID-19是否丧亲与其他 心理病理条件，包括动画，创伤后压力，自杀想法和长期的愤怒 障碍。总而言之，Well提供了一个独特的机会来检查Covid-19死亡之间的关系 以及在社区居住的老年人的大型纵向研究中幸存的配偶的精神病症状 由于配偶丧亲，特别容易受到MDD的影响。