Core-002

核心002

• 批准号: 10206305
• 负责人: Sundeep Khosla
• 金额: $ 58.26万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-18 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10206305
• 关键词: Active Learning; Area; Arizona; Caring; Clinic; Clinical Sciences; Clinical Trials; Collaborations; Communities; Community Health Systems; Community Healthcare; E-learning; Elements; Florida; Goals; Group Practice; Health; Health Personnel; Human; Incentives; Individual; Informatics; Iowa; Laboratories; Leadership; Light; Methods; Minnesota; Mission; Participant; Patient Care; Patients; Positioning Attribute; Process; Research; Research Project Grants; Role; Science; Site; Training; Translation Process; Translational Research; Translations; Wisconsin; Work; Workforce Development; clinical center; clinical practice; community engagement; dissemination research; education research; health care delivery; health care service organization; healthcare community; implementation research; improved; informatics tool; innovation; member; multidisciplinary; patient population; programs; science education; translational pipeline

Clinical and Translational Science (CTS) has been a fundamental and highly valued element of Mayo Clinic since its founding, and Mayo Clinic’s mission “to provide the best care to every patient every day through integrated clinical practice, education, and research” has always aligned well with the NCATS mission. Mayo Clinic is an integrated academic group practice with major sites in Minnesota, Arizona, and Florida; a large community Health System (MCHS) in Minnesota, Wisconsin, and Iowa; and an affiliated national “Care Network” (MCCN). Thus, the Mayo Clinic Center for Clinical and Translational Science (CCaTS) is of national scope. MCHS and MCCN provide unique laboratories for late-stage dissemination and implementation research as well as for the conduct of high-priority clinical trials in community health care organizations. Mayo Clinic is also leading both a PCORI CDRN and a PPRN. These widespread connections, and programs that span the translational spectrum, position Mayo Clinic CCaTS to become a true “hub” for CTS. The present application builds on key accomplishments over the previous 5 years in each of the major areas relevant to the NCATS mission. Mayo CCaTS has mature, innovative programs in workforce development for all members of CTS teams and is diversifying them through online and experiential learning. Incentivizing Team Science has always been part of the institutional culture at Mayo, and we are continuing to build on that strength. Given its role, particularly in Rochester, as a major local and regional provider of health care, community engagement has also been a priority for Mayo Clinic, and a range of methods for bidirectional engagement are proposed. Advances in informatics are also enabling us to connect with new and diverse patient populations. Thus, in light of our institutional traditions and accomplishments over the past 5 years, we believe we are uniquely positioned to accomplish our Specific Aims: Aim 1. Train and maintain an outstanding multidisciplinary CTS workforce, including the entire spectrum of individuals involved in CTS; Aim 2. Eliminate barriers to the work of translation by streamlining methods and processes, including improved and innovative informatics tools, completing the transformation of Mayo’s clinical trial process, and accelerating the implementation of trial results and other discoveries to improve patient care; Aim 3. Engage and incorporate a range of diverse stakeholders as active participants in CCaTS, both in leadership roles and in specific research projects, to improve the process of translation and the delivery of health care, promoting community engagement in research among our Mayo workforce and engaging our local and national communities using both traditional and innovative approaches; and Aim 4. Expand, strengthen, and streamline our regional and national collaborations in all aspects of CTS and education, connecting with our regional and national partners, as well as with the CTSA Consortium, to achieve the ultimate goal of NCATS to improve patient care and human health.

临床和转化科学（CTS）一直是梅奥诊所的基本且高度重视的元素 自成立以来 综合的临床实践，教育和研究一直与NCATS任务保持良好状态。 Mayo Clinic是一项综合学术团体实践，在明尼苏达州，亚利桑那州和佛罗里达州的主要地点； 明尼苏达州，威斯康星州和爱荷华州的大型社区卫生系统（MCHS）；和附属机构“护理 网络”（MCCN）。 范围。 MCHS和MCCN为晚期传播和实施提供独特的实验室 研究以及在社区卫生保健组织中进行高优先临床试验的研究。梅奥 诊所还领导PCORI CDRN和PPRN。这些宽度连接以及程序 跨越翻译光谱，位置梅奥诊所CCAT成为CTS的真正“枢纽”。 本申请基于过去5年的关键成就在每个主要领域 与NCATS任务有关。 Mayo CCAT具有成熟的，创新的劳动力发展计划 CTS团队的所有成员都通过在线和专家学习来使他们多样化。激励 团队科学一直是梅奥（Mayo）制度文化的一部分，我们正在继续以此为基础 力量。鉴于其在罗切斯特（Rochester）的作用，是当地的主要和地区医疗保健提供商， 社区参与也是Mayo诊所的优先事项，并且是双向的一系列方法 提出了参与。信息的进步也使我们能够与新的和潜水员建立联系 患者人群。鉴于我们过去5年的制度传统和成就，我们 相信我们在实现我们的特定目标方面处于独特状态：目标1。训练和维护 出色的多学科CTS劳动力，包括参与CTS的整个个人； 目标2。通过简化方法和流程（包括），消除翻译工作的障碍 改进和创新的信息工具，完成了梅奥临床试验过程的转变， 并加速实施试验结果和其他发现以改善患者护理；目的 3.参与并结合了一系列潜水者的利益相关者，作为CCAT的活跃参与者，都在 领导角色和特定的研究项目，以改善翻译过程和 提供医疗保健，促进社区参与我们的梅奥劳动力和研究 使用传统和创新的方法与我们的本地和民族社区互动；和目标4。 在CTS的各个方面，扩展，更强大和简化我们的区域和国家合作 教育，与我们的地区和国家合作伙伴以及CTSA财团建立联系 实现NCAT的最终目标，以改善患者护理和人类健康。