Research Training in Pulmonary Immunology and Allergy at MGH

MGH 肺部免疫学和过敏研究培训

• 批准号: 10202695
• 负责人: David C Christiani
• 金额: $ 67.84万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10202695
• 关键词: Hypersensitivity; Immunology; Lung; Research Training

Research Training in Pulmonary Immunology and Allergy at MGH is a T32 renewal application that brings together research programs of the Massachusetts General Hospital (MGH) Division of Pulmonary and Critical Care Medicine (DPCCM), Allergy and Clinical Immunology Unit (ACIU), and Center for Immunology and Inflammatory Diseases (CIID). This Training Program was created principally to provide comprehensive training for physician-scientists in the DPCCM and ACIU fellowship programs interested in lung immunology and allergic inflammation. The Program is designed to prepare the next generations of physician-scientists and PhD-scientists to be leaders in lung immunology and allergy related research. In the first 3.5 years, this Program has been highly successful with no unfilled slots and 100% academic retention. In addition, all of the graduates of the Program have published at least one first-author publication and 73% have secured independent funding. In this renewal application we capitalize on this success and momentum and provide training in 10 scientific disciplines: (i) Adaptive Lung Immunity; (ii) Innate Lung Immunity; (iii) Allergic Sensitization, Tolerance & Immunodeficiency; (iv) Lung Injury, Repair & Regeneration; (v) Molecular Epidemiology & Genetics of Lung Disease and Allergy; (vi) Health Care Delivery Science in Pulmonary and Allergy; (vii) Translational & Precision Medicine; (viii) Systems Biology, Single Cell Genomics & Epigenetics; (ix) Microbiome; (x) Novel Imaging Modalities. The Program will have basic, translational, health outcomes and epidemiology components. Specifically we seek to provide: 1) opportunities for mentored research in disciplines that have the potential for high-impact discoveries; 2) outstanding research training through didactics, seminars, and comprehensive mentoring; and 3) an environment and infrastructure that fosters scholarly activity and career development into independent scientists. This application requests 10 training positions that will be allocated to trainees who are committed to 2 to 3 years of research training. Eight MD or MD/PhD candidates will be drawn from the highly competitive DPCCM and ACIU fellowship programs. Two PhD trainees will be chosen from postdoctoral fellows in the laboratories of our mentors who are performing at a high level and who have demonstrated a commitment to careers in pulmonary or allergy research. Two new slots for PhD trainees are being requested based on trainee and mentor feedback indicating that our Program would be strengthened, and the mission of the NIH better served, by having MDs and PhDs train side-by-side. The 28 mentors in this Program were carefully chosen based on their track record of publications, grants, mentoring, collaboration and interest in lung immunology and allergy. MGH provides an outstanding training environment with over 1400 investigators, numerous training grants, research centers, trainee support groups, and over $850 million in research grant awards. Furthermore, opportunities at Harvard Medical School, the Harvard School of Public Health, and the Broad Institute provide additional valuable resources for trainees.

MGH肺免疫学和过敏的研究培训是T32的更新应用 马萨诸塞州总医院（MGH）肺部和关键部门的研究计划 护理医学（DPCCM），过敏和临床免疫学部（ACIU）和免疫学中心和 炎症性疾病（CIID）。该培训计划主要是为了提供全面的 DPCCM和ACIU奖学金计划的医师科学家培训对肺免疫学感兴趣 和过敏性炎症。该计划旨在准备下一代医师科学家和 博士学位科学家是肺免疫学和过敏研究领域的领导者。在最初的3。5年中， 计划非常成功，没有未填充的插槽和100％的学术保留。另外，所有 该计划的毕业生已经发表了至少一份第一名的出版物，有73％的人确保了 独立资金。在此续签应用中，我们利用了这种成功和动力，并提供 在10个科学学科中进行培训：（i）自适应肺免疫； （ii）先天肺免疫； （iii）过敏 灵敏度，耐受性和免疫缺陷； （iv）肺损伤，修复和再生； （v）分子 肺部疾病和过敏的流行病学和遗传学； （vi）肺部和 过敏; （vii）翻译和精密医学； （viii）系统生物学，单细胞基因组学和表观遗传学； （ix）微生物组； （x）新颖的成像方式。该计划将具有基本的，转化的，健康结果，并且 流行病学组成部分。具体我们寻求提供：1）在 具有高影响力发现的学科； 2）通过 教学，研讨会和全面的指导； 3）促进的环境和基础设施 学术活动和职业发展成独立科学家。该申请要求10培训 将分配给致力于2至3年研究培训的学员的职位。八个MD或 MD/PHD候选人将从竞争激烈的DPCCM和ACIU奖学金计划中获取。二 将从在我们的导师实验室中选拔的博士学位学员 高水平，并且表现出对肺或过敏研究中职业的承诺。两个新 根据受训者和导师反馈，要求提供博士学位学员的老虎机，以表明我们的计划 将通过并排使用MDS和PHDS列车来加强NIH的任务。 该计划中的28位导师是根据他们的出版物，赠款， 对肺免疫学和过敏的指导，协作和兴趣。 MGH提供出色的培训 拥有1400多名调查员，众多培训补助，研究中心，学员支持小组的环境， 以及超过8.5亿美元的研究赠款奖。此外，哈佛医学院的机会， 哈佛大学公共卫生学院和广大研究所为学员提供了更多宝贵的资源。