Poly-tobacco use and minority health: Differential risks, transitions, and socio-environmental context

多种烟草的使用和少数民族健康：不同的风险、转变和社会环境背景

• 批准号: 10197785
• 负责人: Steven A. Branstetter
• 金额: $ 44.86万
• 依托单位: VIRGINIA POLYTECHNIC INST AND ST UNIV
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-25 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10197785
• 关键词: Affect; Age; Behavioral; Belief; Biological; Categories; Cessation of life; Chronic Disease; Complex; County; Data; Data Set; Data Sources; Economics; Electronic Nicotine Delivery Systems; Environment; Ethnic Origin; General Population; Geography; Glean; Green space; Health Services Accessibility; Housing; Individual; Investigation; Knowledge; Lead; Light; Link; Measures; Mental Health; Minority; Minority Groups; Nature; Neighborhoods; Nicotine Dependence; Outcome; Perception; Play; Police; Population; Poverty; Price; Public Health; Race; Relative Risks; Reproducibility; Research; Research Design; Risk; Social Environment; Time; Tobacco; Tobacco use; Toxicant exposure; United States National Institutes of Health; Ursidae Family; Work; addiction; base; behavioral study; cohort; combustible tobacco; contextual factors; cultural competence; density; disorder risk; emerging adult; ethnic minority population; experience; health disparity; health inequalities; high risk; lens; low socioeconomic status; minority health; multilevel analysis; novel; polytobacco; polytobacco use; premature; prevent; racial and ethnic; racial diversity; racial minority; smoke-free policy; sociodemographics; socioenvironmental factor; substance use; tobacco control; tobacco products; tobacco user; work-study; young adult

Project Summary Racial and ethnic minorities and individuals of low SES disproportionately experience tobacco-related health inequities, including chronic illness and premature death. Poly-tobacco use—operationalized as the concurrent use of three or more different tobacco products, including electronic nicotine delivery systems (ENDS)—has seen an uptick among emerging adult tobacco users in recent years, notably minorities. The study premise is based the persistent tobacco-related health disparities among minorities and inadequate knowledge of factors that contribute poly-tobacco use or the relative harm. Bearing implications for NIH’s stated need (PAR-17-473 ) for comprehensive socio-environmental investigation as means to advance our knowledge, the study will apply a novel socio-spatial approach to uncover the unique contributions of individual, neighborhood-, county-, and state-level contexts associated with poly use among US emerging adults. The specific aims will shed new light on differential risks (Aim 1), transitions (Aim 2), and the moderating effects of context (Aim 3) of poly- tobacco use across race, ethnicity and low SES. The overriding hypothesis is that minority differences in poly- tobacco use are not explained solely through individual factors but are influenced by the interplay of environments in which emerging adults live, work, study, and play. Through Aim 1, we expect to uncover new information about the relative individual risks or harm among different categories of tobacco users and products, across minority groups—potentially informing both new biological and behavioral studies. Per Aim 2, we will determine factors that influence the transitions from single to dual or poly use over time, which in turn may inform how to prevent escalation to certain tobacco products, especially the most harmful combustible products. Pursuant of Aim 3, because we expect that poly-tobacco use will be best explained by a combination of personal and socio-environmental factors, we expect to uncover rich, new knowledge about contextual influences. We will undoubtedly uncover that individual demographic and behavioral factors explain a significant percentage of the variance in single, dual, and poly use outcomes. Imagine, however, the advancements in tobacco control if we could uncover not only the contributing socio-environmental domains, but also the factors within those domains that explain the remaining percentage—and across diverse racial, ethnic, and low SES populations. The potential impact of such knowledge on tobacco-related health disparities is high.

项目概要 少数种族和族裔以及社会经济地位低的个人不成比例地经历与烟草相关的健康 不平等，包括慢性病和过早死亡——同时进行。 使用三种或更多不同的烟草产品，包括电子尼古丁输送系统（ENDS）—— 近年来，新兴成年吸烟者（尤其是少数群体）的数量有所增加。 基于少数族裔之间持续存在的与烟草相关的健康差异以及对因素的了解不足 导致复合烟草的使用或对 NIH 规定的需求产生相关影响 (PAR-17-473)。 为了将全面的社会环境调查作为增进我们知识的手段，该研究将 应用新颖的社会空间方法来揭示个人、社区、县、 以及与美国新兴成年人中多用途药物使用相关的州级背景，具体目标将产生新的目标。 重点关注差异化风险（目标 1）、转型（目标 2）以及多元环境的调节作用（目标 3） 跨种族、民族和低社会经济地位的烟草使用最重要的假设是，少数群体的差异。 烟草使用不仅仅可以通过个人因素来解释，还受到多种因素相互作用的影响 我们希望通过目标 1 揭示新兴成年人生活、工作、学习和娱乐的环境。 关于不同类别烟草使用者之间的相对个人风险或伤害的新信息，以及 跨少数群体的产品——有可能为新的生物学和行为研究提供信息。 2，我们将确定随着时间的推移影响从单一用途到双重或多用途过渡的因素，其中 反过来可能会告诉您如何防止某些烟草产品升级，尤其是最有害的烟草产品 根据目标 3，因为我们预计复合烟草的使用将通过以下方式得到最好的解释： 个人和社会环境因素的结合，我们期望发现丰富的新知识 毫无疑问，我们将发现个人人口统计和行为因素。 然而，想象一下，单一、双重和多重使用结果的差异的很大一部分。 如果我们不仅能够发现有贡献的社会环境领域， 还包括那些领域内解释剩余百分比的因素——并且跨越不同种族， 这些知识对烟草相关健康差异的潜在影响。 是高的。

项目成果

Nighttime Waking to Smoke, Stress, and Nicotine Addiction.

• DOI: 10.1080/15402002.2021.1992408
• 发表时间: 2022-11
• 期刊: BEHAVIORAL SLEEP MEDICINE
• 影响因子: 3.1
• 作者: Branstetter, Steven A.;Krebs, Nicolle M.;Muscat, Joshua E.
• 通讯作者: Muscat, Joshua E.

Individual Health Determinants That Predict Low Risk of Transitioning to Tobacco Use During Young Adulthood: An In-Depth Examination of Race and Ethnicity.

• DOI: 10.1093/ntr/ntac106
• 发表时间: 2022-08-06
• 期刊: NICOTINE & TOBACCO RESEARCH
• 影响因子: 4.7
• 作者: Horn, Kimberly;Crandell, Ian;Patel, Minal;Rose, Shyanika W.;Schillo, Barbara;Folger, Shanell;Bernat, Debra;Branstetter, Steve
• 通讯作者: Branstetter, Steve

Time to first cigarette of the day and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in adult regular and non-daily smokers: (NHANES) 2007-10.

成年经常吸烟者和非日常吸烟者每天吸第一支烟和 4-(甲基亚硝基氨基)-1-(3-吡啶基)-1-丁醇 (NNAL) 的时间：(NHANES) 2007-10。

• DOI: 10.1016/j.yrtph.2019.104454
• 发表时间: 2019
• 期刊: Regulatory toxicology and pharmacology : RTP
• 作者: Branstetter,StevenA;Nye,RussellT;Muscat,JoshuaE
• 通讯作者: Muscat,JoshuaE