Clinical Scholars Biomedical Research Training Program

临床学者生物医学研究培训计划

• 批准号: 10179325
• 负责人: Ping Chi
• 金额: $ 40.69万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10179325
• 关键词: Biomedical Research; Clinical; Training Programs

PROJECT SUMMARY The Clinical Scholars Biomedical Research Training Program at Memorial Sloan-Kettering Cancer Center (MSKCC) provides a mentored laboratory training experience in cancer research for outstanding MD's or MD/PhD's led by Dr. David Spriggs. The goal of the Program is to prepare highly qualified physician-scientists for a career at the interface of cancer biology and clinical research. The fellows are trained by principal investigators with an exceptionally broad range of scientific interests spanning most areas of modern cancer research. More than one half of the 44 preceptors are physician scientists, who represent strong role models for careers combining laboratory and clinical research and practice. The Program consists of a structured and cohesive two-year curriculum that combines laboratory research, didactic course work in cancer biology, bioinformatics training and career development workshops. Trainees have access to all resources of the Memorial Sloan-Kettering Cancer Center, an instituion in which basic, translational and clinical research activites take place in close proximity in a highly collaborative research environment. The research areas of principal emphasis include: 1) Human cancer biology, mouse models of cancer, genetics and molecular pathology; 2) Drug development and mechanism-based therapeutics; 3) Signals and pathways involved in control of cell proliferation; 4) Regulatory pathways involved in developmental biology and cell differentiation; 5) Cell-cell interactions, adhesion and protein targeting; 6) Tumor immunology, immunotherapy and transplantation biology. The Clinical Scholars Biomedical Research Training Program has had a long and successful training history with nearly all of its graduates continuing in highly productive research careers. Thus, the Program has had signficant impact in meeting the national need for physician-scientists who can play leading roles in translating basic discoveries in cancer biology into patient care.

项目概要 纪念斯隆-凯特琳癌症中心的临床学者生物医学研究培训计划 (MSKCC) 为杰出的医学博士或癌症研究人员提供指导实验室培训经验 医学博士/博士由 David Spriggs 博士领导。该计划的目标是培养高素质的医师科学家 从事癌症生物学和临床研究交叉领域的职业。学员由校长培训 具有广泛科学兴趣的研究人员，涵盖现代癌症的大多数领域 研究。 44 名导师中超过一半是医学科学家，他们是强有力的榜样 适合将实验室和临床研究与实践相结合的职业。该计划包括一个结构化的和 具有凝聚力的两年课程，结合了实验室研究、癌症生物学教学课程工作， 生物信息学培训和职业发展研讨会。学员可以使用所有资源 纪念斯隆-凯特琳癌症中心，一个从事基础、转化和临床研究的机构 活动在高度协作的研究环境中紧密进行。研究领域 主要重点包括： 1) 人类癌症生物学、小鼠癌症模型、遗传学和分子生物学 病理; 2）药物开发和基于机制的治疗； 3）参与的信号和通路 控制细胞增殖； 4）发育生物学和细胞分化涉及的调控途径； 5) 细胞间相互作用、粘附和蛋白质靶向； 6) 肿瘤免疫学、免疫治疗和 移植生物学。临床学者生物医学研究培训计划已经有很长一段时间了 成功的培训历史，几乎所有毕业生都继续从事高产的研究职业。 因此，该计划在满足国家对医师科学家的需求方面产生了重大影响，这些医师科学家能够 在将癌症生物学的基本发现转化为患者护理方面发挥主导作用。