Clinical Scholars Biomedical Research Training Program

临床学者生物医学研究培训计划

基本信息

批准号：
10179325
负责人：
Ping Chi
金额：
$ 40.69万
依托单位：
SLOAN-KETTERING INST CAN RESEARCH
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-01 至 2023-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10179325
关键词：
Biomedical Research Clinical Training Programs

Biomedical Research Clinical Training Programs

项目摘要

PROJECT SUMMARY The Clinical Scholars Biomedical Research Training Program at Memorial Sloan-Kettering Cancer Center (MSKCC) provides a mentored laboratory training experience in cancer research for outstanding MD's or MD/PhD's led by Dr. David Spriggs. The goal of the Program is to prepare highly qualified physician-scientists for a career at the interface of cancer biology and clinical research. The fellows are trained by principal investigators with an exceptionally broad range of scientific interests spanning most areas of modern cancer research. More than one half of the 44 preceptors are physician scientists, who represent strong role models for careers combining laboratory and clinical research and practice. The Program consists of a structured and cohesive two-year curriculum that combines laboratory research, didactic course work in cancer biology, bioinformatics training and career development workshops. Trainees have access to all resources of the Memorial Sloan-Kettering Cancer Center, an instituion in which basic, translational and clinical research activites take place in close proximity in a highly collaborative research environment. The research areas of principal emphasis include: 1) Human cancer biology, mouse models of cancer, genetics and molecular pathology; 2) Drug development and mechanism-based therapeutics; 3) Signals and pathways involved in control of cell proliferation; 4) Regulatory pathways involved in developmental biology and cell differentiation; 5) Cell-cell interactions, adhesion and protein targeting; 6) Tumor immunology, immunotherapy and transplantation biology. The Clinical Scholars Biomedical Research Training Program has had a long and successful training history with nearly all of its graduates continuing in highly productive research careers. Thus, the Program has had signficant impact in meeting the national need for physician-scientists who can play leading roles in translating basic discoveries in cancer biology into patient care.

项目摘要纪念斯隆 - 凯特林癌症中心的临床学者生物医学研究培训计划（MSKCC）为杰出的MD或 MD/PhD由David Spriggs博士领导。该计划的目的是准备高素质的医师科学家在癌症生物学和临床研究界面的职业生涯。研究员受校长培训跨越现代癌症大多数领域的科学兴趣广泛的研究者研究。在44个受体中，超过一半是医师科学家，他们代表了强大的榜样用于结合实验室和临床研究和实践的职业。该程序由一个结构化和结合实验室研究，癌症生物学的教学课程的两年凝聚力两年课程，生物信息学培训和职业发展研讨会。学员可以访问所有资源纪念斯隆 - 凯特林癌症中心，这是一个基础，转化和临床研究的研究所 Activites在高度协作的研究环境中近距离接近。研究领域主要重点包括：1）人类癌症生物学，癌症的小鼠模型，遗传学和分子病理; 2）药物开发和基于机制的治疗剂； 3）涉及的信号和途径控制细胞增殖； 4）参与发育生物学和细胞分化的调节途径； 5）细胞 - 细胞相互作用，粘附和蛋白质靶向； 6）肿瘤免疫学，免疫疗法和移植生物学。临床学者生物医学研究培训计划的长期成功的培训历史，几乎所有毕业生都在延续高生产力的研究职业。因此，该计划在满足国家对医师科学家的国家需求方面具有显着影响在将癌症生物学的基本发现转化为患者护理方面发挥了领导作用。