SouthEast Enrollment Center (SEEC)

东南招生中心 (SEEC)

• 批准号: 10176271
• 负责人: Olveen Carrasquillo
• 金额: $ 1000万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-20 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10176271
• 关键词: Adoption; African American; All of Us Research Program; Behavioral; Caribbean region; Central America; Clinical Research; Communities; Cuba; DNA sequencing; Development; Dominican Republic; Drops; Electronic Health Record; Enrollment; Ensure; Environmental Health; Florida; Genomics; Haiti; Health; Hispanics; Individual; Latino; Link; Medical Records; Minority Recruitment; Participant; Puerto Rico; Sampling; Secure; South America; Technology; West Indies; cohort; cost; genomic data; health data; member; personalized medicine; precision medicine; recruit; success; volunteer

A number of developments over the last decade are promoting bold new projects that can enable the promise of precision or personalized medicine. While DNA sequencing costs continue to drop rapidly, equally important has been the widespread adoption of electronic health records (EHR) allowing for the low cost, highly secure exchange of large amounts of longitudinal health data from individuals. In addition, the increasing consumer adoption of mobile and personal technologies offers the opportunity to link genomic and health data with exposure, behavioral, and other environmental health data on a scale not previously possible. We must ensure that the benefits of these advances are accessible to all. Key to the success of the All of Us Research Program (AoURP) will be the proportional inclusion of diverse groups. This is a major strength of the “SouthEast Enrollment Center” (SEEC) consortium. SEEC will recruit 93,000 full participants from Florida and Georgia into AoURP, including approximately 30% Hispanic/Latino and 30% Black/African American volunteers. Importantly, half of the Hispanics will come from the Caribbean (e.g. Cuba, Puerto Rico and the Dominican Republic) and the other half from South and Central America. Our sample of Blacks will include participants from Haiti and English-speaking Caribbean islands. The Consortium will be spearheaded by four leading academic health centers in Florida and Georgia. Each member brings a considerable track record of establishing genomic cohorts, recruiting minorities into clinical research, forming community engagement partnerships, and sharing medical records across large networks (e.g. all participate in PCORnet).

在过去的十年中，许多事态发展促进了大胆的新项目，这些项目可以实现诺言 尽管DNA测序成本继续迅速下降，但同样重要的是采用电子健康记录（EHR），允许低成本，高度安全地交换来自个人的大量纵向健康数据。此外，移动和个人技术的消费者采用越来越多，还可以将基因组和健康数据与以前不可能的规模联系起来，将基因组和健康数据与暴露，行为和其他环境健康数据联系起来。我们必须确保所有人都能获得这些进步的好处。我们全部研究计划（AOURP）成功的关键将是不同群体的比例包含。 这是“东南入学中心”（SEEC）财团的主要优势。 SEEC将招募93,000名佛罗里达和佐治亚州的全面参与者，其中包括约30％的西班牙裔/拉丁裔和30％的黑人/非裔美国人志愿者。重要的是，一半的西班牙裔将来自加勒比海（例如古巴，波多黎各和多米尼加共和国），另一半来自南美洲和中美洲。我们的黑人样本将包括来自海地和讲英语的加勒比群岛的参与者。该财团将由佛罗里达州和佐治亚州的四个领先的学术保健中心率领。每个成员都带来了建立基因组队列，招募少数民族进入临床研究，建立社区参与伙伴关系以及在大型网络上共享医疗记录（例如所有参与PCORNET）的考虑记录。