Chemistry: Analytical Track 4: Allergen Testing

化学：分析轨道 4：过敏原测试

• 批准号: 10174018
• 负责人: SINISA URBAN
• 金额: $ 5.5万
• 依托单位: MARYLAND STATE DEPARTMENT OF HEALTH
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10174018
• 关键词: Chemistry; Analytical; Track; Allergen; Testing

SUMMARY: CHEMISTRY ANALYTICAL TRACK 4 (DEVELOPMENT: ALLERGENS) Trace levels of an allergen can induce anaphylactic shock leading to death within minutes. The core tenet of this large and multifaceted proposal is to contribute a comprehensive and integrated food protection laboratory hub to the Food Emergency Response Network (FERN) that is capable of analyzing many different foods across a diversity of threat priorities. MDH Laboratories Administration currently lacks the ability to analyze foods for any allergens, and therefore has placed a priority on developing allergen testing capability for our Food Chemistry Laboratory. A robust, sensitive, and facile test for detecting 15 common allergens has just become available. We will follow the detailed validation ‘roadmap’ established in a recently published article to implement the xMAP FADA assay in our Food Chemistry Laboratory. Importantly, our Food Chemistry Laboratory is equipped with a dedicated Food Kitchen that includes an oven and range for the controlled preparation of food, as required for this validation. Our activities under this developmental track will focus on achieving the prescribed Specific Aims.

摘要：化学分析轨道4（开发：过敏原） 过敏原的痕量水平会在几分钟内诱导过敏性冲击。核心宗旨 这个大型多方面的建议是为全面而综合的食物做出贡献 保护实验室中心的食品应急响应网络（FERN） 分析各种威胁重点的许多不同食物。 MDH实验室管理 目前缺乏分析任何过敏原食物的能力，因此已优先考虑 为我们的食物化学实验室开发过敏原检测能力。强大，敏感，并且 可用于检测15种常见过敏原的便利测试。我们将遵循详细的 在最近发表的文章中建立的验证“路线图”，以实施XMAP FADA分析 我们的食物化学实验室。重要的是，我们的食物化学实验室配备了 专用的食品厨房，包括烤箱和可控食物准备的范围， 根据此验证的要求。我们在这种发展轨道下的活动将重点在于 规定的具体目的。