Biobehavioral Research Training Program in Symptom Science

症状科学生物行为研究培训项目

• 批准号: 10166235
• 负责人: CHRISTINE A. MIASKOWSKI
• 金额: $ 9.52万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10166235
• 关键词: Research Training; Training Programs; biobehavior; symptom science

Project Summary The science underlying symptom etiology, the symptom experience, and symptom management has advanced substantially over the last few decades. Yet little is known about the biobehavioral underpinnings of many symptoms or the ways in which biological and behavioral factors interact during the symptom experience. Even less is known about symptom management strategies that can effectively target both biological and behavioral components of the symptom response. Genomics represents an essential focus for the advancement of biobehavioral symptom science and for provision of nursing care that is individualized to the precise needs of patients. There has been growing recognition of the critical role that genomics will play in enabling effective assessment and management of symptoms. The purpose of this supplement is to prepare two predoctoral nursing students to conduct genomic research in symptom science, and to augment the genomics content in an existing training program that is preparing nurse scientists for biobehavioral research careers in symptom science. Upon completion of the program, trainees will have the knowledge and skills necessary to: 1) design and conduct genomic research on symptoms and health-related outcomes, 2) employ multi-method, genomic approaches to the study of symptoms and the testing of symptom management strategies, and 3) translate genomic research findings into recommendations for symptom prevention, assessment and management. The predoctoral curriculum includes standard PhD requirements at UCSF School of Nursing, 3 symptom-specific courses, 4 courses addressing genomics (candidate gene analysis, analysis and interpretation of gene expression data, use of non-invasive biospecimens for analysis of DNA markers, ethical considerations in genomic and genetic research), and a research residency in a genomics laboratory. The interdisciplinary faculty group has significant expertise in genomics and symptom science, including six faculty in the School of Nursing and six affiliated faculty from the School of Medicine at UCSF. Preparing nurse scholars to advance symptom science through rigorous research training in genomic research is essential for improved understanding of the symptom experience and better management of symptoms by patients and clinicians. The UCSF School of Nursing is in a unique position to provide genomic training in symptom science because of its strong research programs in the field, its history of successful research training, and its ongoing collaboration with other Departments, Centers and Institutes at UCSF that are involved in both genomic and symptom-related research.

项目摘要 科学的症状病因，症状经验和症状管理 在过去的几十年中，已经取得了长足的进步。然而，关于生物行为的知之甚少 许多症状的基础或生物学和行为因素相互作用的方式 在症状经历中。关于症状管理策略的了解更少 这可以有效地针对症状反应的生物学和行为成分。 基因组学是进步生物行为症状科学的重要重点 并提供针对患者确切需求的个性化护理护理。那里 人们对基因组学将在实现有效方面发挥的关键作用的认识日益认识 评估和管理症状。该补充的目的是准备两个 专业护理专业的学生在症状科学领域进行基因组研究，并增加 现有培训计划中的基因组学内容正在为护士科学家做好准备 症状科学生物行为研究职业。计划完成后，学员 将具有以下必要的知识和技能：1）设计和进行基因组研究 症状和与健康相关的结果，2）采用多方法，基因组方法 症状研究和症状管理策略的测试，3）翻译 基因组研究结果提出了预防症状，评估和 管理。专用课程包括UCSF学校的标准博士学位要求 护理，3个特定症状的课程，4个针对基因组学的课程（候选基因 基因表达数据的分析，分析和解释，非侵入性生物测量的使用 为了分析DNA标记，基因组和遗传研究中的道德考虑）以及 基因组实验室的研究居留。跨学科教师团体有重要的 基因组学和症状科学方面的专业知识，包括护理学院的六个教师 UCSF医学院的六个会员教师。准备护士学者进步 通过严格的基因组研究研究培训症状科学对于 通过 病人和临床医生。 UCSF护理学院处于独特的位置，可以提供基因组 症状科学培训，因为其在该领域的强大研究计划，其历史 成功的研究培训及其与其他部门，中心和 UCSF的研究所涉及基因组和症状有关的研究。