Post-Hurricane Cancer Care: Patient Needs after Hurricane Maria

飓风后癌症护理：飓风玛丽亚后的患者需求

基本信息

批准号：
10172476
负责人：
Eida Maria Castro
金额：
$ 21.27万
依托单位：
PONCE SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-17 至 2023-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10172476
关键词：
Affect Alcohols Anxiety Biological Biological Markers Biological Process Blood Banks COVID-19 COVID-19 pandemic Camping Cancer Patient Caring Catecholamines Categories Cessation of life Chronic Complement Data Disasters Earthquakes Eating Behavior Economics Environmental Hazards Exercise Exposure to Floods Funding Geological Survey Grant Hair Health Health Services Accessibility Health behavior Healthcare Home environment Homelessness Hormones Hurricane Hydrocortisone Inflammation International Island Knowledge Lead Malignant Neoplasms Measures Medical Mental Depression Mental Health Minority Groups Natural Disasters Outcome Parents Participant Pathway interactions Patient Care Patient Self-Report Patients Physiological Pilot Projects Positioning Attribute Principal Investigator Property Puerto Rican Puerto Rico Reporting Research Sampling Scientist Smoking Behavior Social isolation Social support Stress Structure Time Unemployment United States biological adaptation to stress cancer care circulating biomarkers cohort comorbidity cytokine environmental stressor ethnic minority population experience food shortage hazard health care availability health care quality health care service health disparity inflammatory marker innovation minority health multilevel analysis pandemic disease parent grant perceived stress predictive modeling programs psychologic psychological stressor recruit social stressor stress management stressor tumor progression

项目摘要

PROJECT SUMMARY Studies evaluating the effects of natural disasters on cancer outcomes and disparities are scarce, and to the study team’s knowledge; none have examined the impact of exposure to multiple disasters, particularly in ethnic minority groups. Currently, the team is expanding assessments to include the impact of COVID-19 and the earthquakes’ secondary hazards (social isolation, unemployment, healthcare services disruption, structural damage) on stress biomarkers and changes in multilevel determinants of health. The proposed supplement will complement the scope of the parent R21 (1R21MD013674) by: 1) expanding recruitment to include additional cancer patients (+75) and controls (+75) who were exposed to Maria, the 2020 earthquakes, and the COVID-19 pandemic; 2) identifying patients’ unmet psychological and medical needs resulting from the aftermath of the 2020 earthquakes and the COVID-19 pandemic, and; 3) examining the impact of Maria, the earthquakes, and the COVID-19 pandemic on multilevel factors relevant to health outcomes. The proposed supplement project will shift current research paradigms in health outcomes after natural disasters by exploring the physiological effects of extreme stressors on biological processes known to affect cancer progression and comorbid conditions, including inflammation and stress hormones. By expanding the parent grant’s scope to include the 2020 earthquakes and COVID-19 pandemic, the study team will increase the understanding of the effects of multiple disaster stressors.

项目摘要评估自然灾害对癌症结局和差异的影响的研究很少，而对学习团队的知识；没有人检查过暴露于多种灾难的影响，尤其是在种族中少数群体。目前，该团队正在扩大评估，以包括Covid-19和The的影响地震的次要危害（社会隔离，失业，医疗保健服务中断，结构性损坏）压力生物标志物和健康决定剂的变化。拟议的补充剂将完成父母R21（1R21MD013674）的范围：1）扩大招聘癌症患者（+75）和对照（+75）暴露于玛丽亚，2020年地震和Covid-19 大流行; 2）确定患者的未满足的心理和医学需求 2020年地震和19009年大流行，以及； 3）检查玛丽亚，地震和与健康结果相关的多层次因素大流行。拟议的补充项目将通过探索生理学来改变自然灾害后健康结果的当前研究范例极端压力源对已知影响癌症进展和合并的生物过程的影响条件，包括炎症和应激激素。通过扩大父母赠款的范围以包括 2020年地震和19009年大流行，研究团队将增加对多个灾难压力源。